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Massachusetts Paid Clinical Trials
A listing of 3147 clinical trials in Massachusetts actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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Clinical Trial Phase
Massachusetts is currently home to 3147 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Boston, Worcester, Springfield and Burlington. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Type 2 Diabetes Clinical Trial
Recruiting
Can changing your breakfast improve your type 2 diabetes? If you have an HbA1C of 7.0% or higher, you are invited to participate in an online study at the University of Michigan.
Conditions:
Type 2 Diabetes
Diabetes Mellitus Type 2 in Obese
Diabetes Type Two
Type 2 Diabetes Mellitus
Diabete Type 2
Featured Offer
Lose Weight with GLP-1 Medications
Recruiting
Policy Lab has partnered with CareGLP to offer trusted access to GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma
Recruiting
Resection of glioblastoma in or near functional brain tissue is challenging because of the proximity of important structures to the tumor site. To pursue maximal resection in a safe manner, mapping methods have been developed to test for motor and language function during the operation. Previous evidence suggests that these techniques are beneficial for maximum safe resection in newly diagnosed grade 2-4 astrocytoma, grade 2-3 oligodendroglioma, and recently, glioblastoma. However, their effects... Read More
Gender:
ALL
Ages:
90 years and below
Trial Updated:
02/20/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Glioblastoma, IDH-wildtype, Glioblastoma, Glioblastoma Multiforme of Brain, Astrocytoma, Malignant, Brain Neoplasms, Brain Neoplasms, Adult, Malignant, Brain Neoplasms, Adult, Recurrent Adult Brain Tumor, Recurrent Glioblastoma
The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)
Recruiting
A greater extent of resection of the contrast-enhancing (CE) tumor part has been associated with improved outcomes in high-grade glioma patients. Recent results suggest that resection of the non-contrast-enhancing (NCE) part might yield even better survival outcomes (supramaximal resection, SMR). Therefore, this study evaluates the efficacy and safety of SMR with and without mapping techniques in HGG patients in terms of survival, functional, neurological, cognitive, and quality of life outcomes... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
02/20/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Glioblastoma, High-grade Glioma, Glioblastoma, IDH-wildtype, Glioblastoma, IDH-mutant, Glioblastoma Multiforme, Adult, Astrocytoma, Grade IV, Astrocytoma, Grade III, Astrocytoma, Malignant, Brain Neoplasms, Brain Neoplasm, Primary, Brain Neoplasms, Adult, Brain Neoplasm, Malignant
Evaluation of Hemodynamics in People With Untreated Preeclampsia Using Echocardiography
Recruiting
The goal of this observational trial is to determine the resting cardiac output (CO) using transthoracic echocardiography (TTE) in a cohort of people with untreated preeclampsia, and a cohort of healthy normotensive pregnant people.
Gender:
FEMALE
Ages:
Between 18 years and 55 years
Trial Updated:
02/20/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Preeclampsia
Adapt2Quit - An Adaptive Motivational System for Socio-Economically Disadvantaged Smokers
Recruiting
The goal of this research is to test the Adapt2Quit computer program that uses participant input (message rating on how much the text motivational message might influence one to quit smoking) to select and text motivational messages that are more likely to help a user stop smoking. This Adapt2Quit system will be compared with a quitline facilitation-only control (text messages will be sent to facilitate quitline use). The primary research hypothesis is that the Adapt2Quit recommender-selected me... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
02/20/2024
Locations: Baystate Health, Springfield, Massachusetts
Conditions: Tobacco Smoking
SpermQT Prospective Observational Trial
Recruiting
The goal of the study is to validate the ability of the Epigenetic Sperm Quality Test (SpermQT) to assess a man's sperm quality and corresponding success of infertility treatments.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
02/19/2024
Locations: Boston IVF, Waltham, Massachusetts
Conditions: Male Infertility
Granzyme B PET Imaging Drug as a Predictor of Immunotherapy Response to Checkpoint Inhibitors
Recruiting
First in Human Safety of \[68Ga\]-NOTA-hGZP PET Imaging in subjects with cancer undergoing treatment with a checkpoint inhibitor either as a monotherapy of in combination I-O therapy
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/17/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Solid Tumor, Unspecified, Adult, Lymphoma
A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough
Recruiting
This is a randomized, double-blind, placebo-controlled, parallel-arm, Phase 3 study of BLU-5937 in participants with Refractory Chronic Cough (RCC).
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/14/2024
Locations: Infinity Medical Research Inc, North Dartmouth, Massachusetts
Conditions: Refractory Chronic Cough
Angiotensin-Neprilysin Inhibition in Hemodialysis Initiation
Recruiting
This randomized placebo-controlled clinical trial will evaluate the effect of sacubitril/valsartan (compared with placebo) on echocardiographic measures of hypervolemia, preservation of residual renal function, and key safety parameters in incident hemodialysis patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2024
Locations: Brigham and Women's, Boston, Massachusetts
Conditions: Hemodialysis
A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH
Recruiting
An open label single-arm clinical trial to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of HMPL-306 in subjects with advanced relapsed, refractory, or resistant hematological malignancies that harbor IDH mutations.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2024
Locations: University of Massachusetts Medical School, Worcester, Massachusetts
Conditions: Isocitrate Dehydrogenase Gene Mutation
MAnnitol for Blood Pressure Stability in HemoDialysis (MAP-HD)
Recruiting
This proposal will measure the effects of mannitol administration versus placebo in hypotensive-prone, adult, maintenance hemodialysis patients with respect to changes in patient symptoms and blood pressure stability.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2024
Locations: Brigham and Women's, Boston, Massachusetts
Conditions: Hemodialysis Complication, Hemodynamic Instability
Initial Pain Management in Pediatric Pancreatitis: Opioid vs. Non-Opioid
Recruiting
This will be a phase 2, single-center, unblinded randomized controlled pilot trial of two arms comparing opioid-sparing analgesia to the current Boston Children's Hospital institutional practice which has been reported to predominantly include administration of opioids as a first-line analgesic to pediatric patients who present to the emergency department with a diagnosis of acute pancreatitis (AP). This is a pilot trial for which many outcomes have not previously been studied in the pediatric A... Read More
Gender:
ALL
Ages:
21 years and below
Trial Updated:
02/13/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Acute Pancreatitis
Adjunctive Mindfulness During Opioid Tapering for patientS With Chronic Pain (The AMOS Study)
Recruiting
This study is a Randomized Controlled Trial exploring the effects of a Mindfulness interventions in reducing pain interference and opioid dose in patients with Chronic Low Back Pain. A total of 200 opioid-using patients with chronic pain, male and female participants will be enrolled, with a need for 160 completers. Patient will be randomly assigned into the Mindfulness-Oriented Recovery Enhancement or the Psychoeducation comparison control group.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2024
Locations: Brigham and Women's Hospital, Chestnut Hill, Massachusetts
Conditions: Low Back Pain