Colorado is currently home to 1810 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A PIVOTAL STUDY EVALUATING SAFETY and EFFICACY of the SHIRATRONICS MIGRAINE THERAPY SYSTEM
NCT06167655
Recruiting
Prospective, multi-center, double blind, randomized, sham-controlled study to evaluate neuromodulation in patient with chronic migraine. The study hypothesis to be tested is the mean reduction in mean monthly headache days between patients in treatment versus sham.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/04/2025
Locations: Barolat Neuroscience, Denver, Colorado
Conditions: Headache Migraine Chronic
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Effect of Amino Acids on Hepatic Fat Content in Adolescents (AMINOS Study)
NCT05935826
Recruiting
Participants 13-18 years of age with extra fat stored in the liver will be randomly assigned to a protein supplement or placebo "fake supplement" for 2 months to see if the participants who get the protein supplement have less fat in the liver compared to participants who were in the placebo group. After the 2 month intervention, all participants can continue the study and will all receive the protein supplement for an additional 10-months.
Gender:
ALL
Ages:
Between 13 years and 18 years
Trial Updated:
03/04/2025
Locations: Univeristy of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Hepatic Steatosis, NAFLD, Adolescent Obesity
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Expanding Exercise Programming for Veterans Through Telehealth
NCT05666167
Recruiting
The goal of this study is to evaluate the acceptability and feasibility of a group telehealth exercise program for Veterans with lower extremity osteoarthritis (OA). Methods: This is a randomized pilot trial where Veterans (n=50) receive a group telehealth exercise program (3 months), followed by an exercise maintenance phase (6 months) that includes either text messaging alone or text messaging plus group telehealth exercise booster sessions. The primary outcomes for this study are feasibility... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2025
Locations: Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora, Colorado
Conditions: Arthritis
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Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children
NCT04993859
Recruiting
The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.
Gender:
ALL
Ages:
Between 5 years and 13 years
Trial Updated:
03/04/2025
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Survivors of Childhood Cancer, Bladder Dysfunction
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Study to Assess EN3835 in the Treatment of Plantar Fibromatosis (Also Known as Ledderhose Disease)
NCT06151197
Recruiting
This study will assess the efficacy, safety, and tolerability of EN3835 compared to placebo in the treatment of PFI (also known as Ledderhose disease).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/03/2025
Locations: Endo Site 47, Johnstown, Colorado
Conditions: Plantar Fibromatosis, Ledderhose Disease
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Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
NCT04817618
Recruiting
The Primary Completion Date and Study Completion Date have been updated to reflect completion of the adolescent cohort, which has been added to the protocol. The study is designed as a multicenter, randomized, double-blind, parallel group, placebo-controlled study to evaluate the efficacy and safety of iptacopan (LNP023) in complement 3 glomerulopathy.
Gender:
ALL
Ages:
Between 12 years and 60 years
Trial Updated:
03/01/2025
Locations: Childrens Hospital Colorado, Aurora, Colorado
Conditions: C3G
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Stop, Focus, Plan, and Change: Predicting Parent and Child Responses to a Brief, Telehealth Parent Training
NCT06505980
Recruiting
This study will look at who does not improve after doing a behavioral parent training program briefly through telehealth. It will also study ways to make the intervention better for those that do not improve.
Gender:
ALL
Ages:
Between 3 years and 5 years
Trial Updated:
02/28/2025
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Behavioral Problem, Irritable Mood, Parenting, Stress
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Direct-to-patient Teledermatology and Computer-assisted Diagnosis
NCT05128006
Recruiting
This study will examine access to dermatology care. The operational partner will implement a direct-to-new patient teledermatology clinical care pathway while the research will study the effects of that implementation, use data associated with deployment to develop and test an Artificial Intelligence system, and understand key stakeholders' attitudes regarding and readiness for remote dermatology care.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/28/2025
Locations: Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora, Colorado
Conditions: New Patient Use of Teledermatology Mobile App
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A Study of CUSP06 in Patients with Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors
NCT06234423
Recruiting
This phase 1 study will evaluate the safety, tolerability, pharmacokinetics, and efficacy of CUSP06 in patients with platinum-refractory/resistant ovarian cancer and other advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2025
Locations: Sarah Cannon Research Institute at HealthONE, Denver, Colorado
Conditions: Ovarian Cancer, Solid Tumor
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Safety and Tolerability of Open-Labeled Iloperidone in Adolescents
NCT05648591
Recruiting
To evaluate the safety and tolerability of iloperidone in adolescent patients with schizophrenia or bipolar I disorder for up to 52 weeks of treatment.
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
02/27/2025
Locations: Vanda Investigational Site, Denver, Colorado
Conditions: Schizophrenia, Bipolar I Disorder
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Collection and Storage of Tissue and Blood Samples From Patients With Cancer
NCT02474160
Recruiting
This study collects and stores tissue and blood samples from patients with cancer. Collecting and storing samples of tissue and blood from patients with cancer to study in the laboratory may help scientists create new and better models to learn about cancer and to test new cancer drugs.
Gender:
ALL
Ages:
2 months and above
Trial Updated:
02/27/2025
Locations: UCHealth University of Colorado Hospital, Aurora, Colorado
Conditions: Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm
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Structural Conditions and Health After Release From Prison
NCT05989282
Recruiting
People released from prison experience two times higher cardiovascular (CV) mortality than the general population, have a high prevalence of poor CV health and increased risk of CV events within 2 years of release. Access to high quality healthcare following release from prison is key to preventing poor health and CV outcomes. Our study team will investigate facilitators and barriers to health care access experienced by people released from prison.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2025
Locations: Kaiser Permanente Institute for Health Research, Aurora, Colorado
Conditions: Cardiovascular Diseases, Health Care Utilization
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