Colorado is currently home to 1786 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
XmAb®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer
NCT05005728
Recruiting
This Phase 2 study will investigate the safety and clinical activity of vudalimab (XmAb20717) alone or in combination with standard of care anticancer therapies in patients with metastatic castration-resistant prostate cancer (mCRPC) who have progressed on prior therapy.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Rocky Mountain Cancer Centers, Lone Tree, Colorado
Conditions: Metastatic Castration-Resistant Prostate Cancer
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Open Versus Arthroscopic Stabilization of Shoulder Instability with Subcritical Bone Loss: the OASIS Trial
NCT04809064
Recruiting
This clinical trial will investigate the effects of three surgical procedures and the associated post-operative rehabilitation to optimize time to return to military duty, work and sports, and patient-reported physical function for military personnel and civilians with traumatic anterior shoulder instability and 10-20% glenoid bone loss.
Gender:
ALL
Ages:
Between 17 years and 50 years
Trial Updated:
10/08/2024
Locations: Evans Army Community Hospital, Fort Carson, Colorado
Conditions: Shoulder Dislocation, Glenohumeral Dislocation, Anterior Shoulder Dislocation
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In Vitro Maturation of Human Eggs
NCT06633120
Recruiting
CCRM Fertility, a global pioneer in fertility treatment, research and science, is seeking participants for a new study on in vitro maturation (IVM). IVM requires less hormones to stimulate the ovaries than IVF, making it more affordable than IVF with fewer side effects. Participants that qualify for the study will receive a free cycle of IVM treatment at CCRM Fertility and including a new patient consultation, fertility testing, preimplantation genetic testing for aneuploidies (PGT-A), anesthesi... Read More
Gender:
FEMALE
Ages:
38 years and below
Trial Updated:
10/07/2024
Locations: Colorado Center for Reproductive Medicine, Lone Tree, Colorado
Conditions: Healthy, PCOS, PCOS (Polycystic Ovary Syndrome), Ovarian Reserve, Infertility, Infertility Female, Infertility of Tubal Origin, Infertility Poly Cystic Ovary, AMH, In Vitro Maturation, IVM, IVF
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A Study to Evaluate ATP150/ATP152, VSV-GP154 and Ezabenlimab in Patients With KRAS G12D/G12V Mutated PDAC (KISIMA-02)
NCT05846516
Recruiting
The goal of this clinical trial is to test an experimental treatment (immunotherapy) in pancreatic cancer patients. The main research objectives are: * to evaluate if the KISIMA-02 treatment is safe and well-tolerated (first part) * to evaluate if the KISIMA-02 treatment has an impact on the time to observe a possible reappearance of the tumor (second part) Participants will receive: i) a therapeutic protein vaccine ATP150 or ATP 152 ii) a viral vector VSV-GP154 iii) an immune checkpoint inhi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Pancreatic Ductal Adenocarcinoma
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Aspiration in Acute Respiratory Failure Survivors 2
NCT05108896
Recruiting
The purpose of this study is to learn more about problems with swallowing that could develop in patients who are very sick and need a machine to help them breathe.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: University of Colorado, Aurora, Colorado
Conditions: Dysphagia, Aspiration
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Defining the Genetic Etiology of Suppurative Lung Disease in Children and Adults
NCT04702243
Recruiting
The investigators will utilize a systematic approach for the diagnostic evaluation of patients to identify characteristics which may distinguish between Primary Immunodeficiency (PID) disorders versus Primary Ciliary Dyskinesia (PCD).
Gender:
ALL
Ages:
Between 5 years and 45 years
Trial Updated:
10/07/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Primary Ciliary Dyskinesia, Primary Immune Deficiency, Kartagener Syndrome
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The Pediatric Spine Foundation
NCT02540915
Recruiting
The Pediatric Spine Foundation is a registry designed to assist spine surgeons to efficiently identify and track patients with chest wall and spinal disorders.
Gender:
ALL
Ages:
17 years and below
Trial Updated:
10/07/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Chest Wall and Spinal Disorders
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Chronic Cannabis Smoking, Oxidative Stress and the Pulmonary Innate Immune Response
NCT02480283
Recruiting
This study plans to evaluate the effects of chronic cannabis smoking on lung health by evaluating its effects on pulmonary health, lung physiology and alveolar macrophage function.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
10/07/2024
Locations: University of Colorado, Denver, Aurora, Colorado
Conditions: Cannabis Smoking, Oxidative Stress
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Effect of Alcohol and Drugs of Abuse on Immune Function in Critically Ill Patients With Respiratory Failure
NCT02299921
Recruiting
This study plans to learn more about people who are sick in the hospital with a lung infection, or respiratory failure. Respiratory failure, or severe lung failure, is a life-threatening disease. When it happens, the lungs have trouble carrying out their normal function of getting oxygen into the blood, and removing carbon dioxide from the body. Investigators are conducting this study to see what drinking too much alcohol, using tobacco products, or using drugs (both legal and illegal) may do to... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
10/07/2024
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Infection, Alcohol Abuse, Drugs of Abuse, Lung Injury
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A Study About How TAK-881 is Processed by the Body and Side Effects in People With Primary Immunodeficiency Diseases
NCT05755035
Recruiting
The main aim of this study is to evaluate the PK, safety, tolerability and immunogenicity of subcutaneous (SC) administration of TAK-881 in adult and pediatric participants with PIDD and compare them to HYQVIA in participants 16 years old and older. The participants will be treated with TAK-881/HYQVIA or HYQVIA/TAK-881 with the same dose and dosing interval of immunoglobulin for up to 51 weeks (for participants greater than or equal to \[\>=\]16 years) and only with TAK-881 for up to 27 weeks (... Read More
Gender:
ALL
Ages:
2 years and above
Trial Updated:
10/04/2024
Locations: National Jewish Medical And Research Center, Denver, Colorado
Conditions: Primary Immunodeficiency Diseases (PID)
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Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation
NCT05609578
Recruiting
Study CA239-0010 is an open-label, Phase 2 clinical trial evaluating the clinical efficacy of adagrasib in combination with pembrolizumab and chemotherapy in the first-line setting for patients with advanced NSCLC with TPS ≥ 1%, TPS \<50% and KRAS G12C mutation
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/04/2024
Locations: Local Institution - 017-872-I, Aurora, Colorado
Conditions: Advanced NSCLC, Metastatic Lung Cancer
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Biospecimen and Medical Data Collection and Tumor Biopsy in Creating Research Tissue Registry in Patients with Inflammatory or Invasive Breast Cancer
NCT00477100
Recruiting
This trial studies the biospecimen and medical data collection in creating a research tissue registry in patients with inflammatory or invasive breast cancer. Collecting medical data and storing samples of blood, tissue, and stool from patients with inflammatory breast cancer to study in the laboratory may help doctors find better ways to treat and study inflammatory breast cancer in the future.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/04/2024
Locations: Banner - MD Anderson Cancer Center - Northern Colorado, Greeley, Colorado
Conditions: Inflammatory Breast Carcinoma, Invasive Breast Carcinoma, Second Primary Malignant Neoplasm
Register for Updates