Colorado is currently home to 1784 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effects of Physical and Psychosocial Stress on Functional Hypothalamic Amenorrhea in Exercising Women
NCT05967819
Recruiting
The goal of this clinical trial is to determine how changes in exercise and psychosocial stress may influence the risk of menstrual cycle irregularities in female runners and cyclists. The main questions it aims to answer are: * Does the implementation of exercise or psychosocial stress effect circulating reproductive hormones (i.e., estradiol, progesterone, luteinizing hormone) and menstrual cycle length? * Is there an additive effect of combined exercise and psychosocial on circulating reprod... Read More
Gender:
FEMALE
Ages:
Between 18 years and 35 years
Trial Updated:
05/29/2024
Locations: University of Colorado Colorado Springs, Colorado Springs, Colorado
Conditions: Amenorrhea Secondary
Register for Updates
Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma
NCT05798897
Recruiting
This study is a Phase 1 multicenter study with a Dose Escalation and Dose Expansion evaluating safety and efficacy of MT-601 administration to patients with Relapsed or Refractory Lymphoma. The starting dose administered is 200 x 10\^6 cells (flat dosing).
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
05/29/2024
Locations: Colorado Blood Cancer Institute (Sarah Cannon), Denver, Colorado
Conditions: Non-Hodgkin Lymphoma, Adult, Non-Hodgkin Lymphoma, Refractory, Non-Hodgkin Lymphoma, Relapsed, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Hodgkin Lymphoma, Adult, Hodgkin's Lymphoma, Relapsed, Adult
Register for Updates
Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults With Relapsed/Refractory Acute Myeloid Leukemia
NCT03971799
Recruiting
This phase 1/2 trial aims to determine the safety and feasibility of antiCD33 chimeric antigen receptor (CAR) expressing T cells (CD33CART) in children and adolescents/young adults (AYAs) with relapsed/refractory acute myeloid leukemia (AML). The trial will be done in two phases: Phase 1 will determine the maximum tolerated dose of CD33CART cells using a 3+3 trial design, with dose-escalation for autologous products separated from dose-escalation for an allogeneic arm. Phase 2 is an expansion ph... Read More
Gender:
ALL
Ages:
Between 1 year and 35 years
Trial Updated:
05/29/2024
Locations: Children's Hospital of Colorado, Aurora, Colorado
Conditions: Acute Myelogenous Leukemia
Register for Updates
Safety and Efficacy of Radio Frequency for the Treatment of Mild to Severe Inflammatory Acne
NCT05830968
Recruiting
The aim of this trial is to evaluate the safety and efficacy of the InMode RF Pro System with the Morpheus8 face tip (24 pins) applicator for the treatment of mild, moderate and severe, facial acne vulgaris
Gender:
ALL
Ages:
16 years and above
Trial Updated:
05/28/2024
Locations: AboutSkin Research, LLC, Greenwood Village, Colorado
Conditions: Inflammatory Acne Vulgaris
Register for Updates
Hydrus® Microstent New Enrollment Post-Approval Study
NCT04553523
Recruiting
The purpose of this post-approval study is to evaluate the rate of Hydrus Microstent malposition and associated clinical sequelae occurring within 24 months post-operation. Qualified subjects will undergo uncomplicated cataract surgery with placement of a monofocal intraocular lens (IOL), followed by implantation of the Hydrus Microstent.
Gender:
ALL
Ages:
45 years and above
Trial Updated:
05/28/2024
Locations: Eye Center of Northern Colorado, Loveland, Colorado
Conditions: Primary Open Angle Glaucoma
Register for Updates
Testicular Tissue Cryopreservation (TTC)
NCT06387498
Recruiting
The "Testicular Tissue Cryopreservation" study is open to a subset of patients facing disease or treatment regimens that could lead to infertility (gonadotoxic therapies). For some of these patients, experimental testicular tissue cryopreservation is the only fertility preservation option available. The overall objective of this study is to determine the feasibility and acceptability of testicular tissue cryopreservation in male patients of all ages who have a condition or will undergo a treatme... Read More
Gender:
MALE
Ages:
All
Trial Updated:
05/24/2024
Locations: University of Colorado, Aurora, Colorado
Conditions: Fertility Issues
Register for Updates
A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma
NCT05757102
Recruiting
The primary purpose of this study is to evaluate the effects of Fluticasone Furoate (FF)/ Umeclidinium (UMEC)/ Vilanterol (VI) on lung function compared with FF/VI after 24 weeks of treatment.
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
05/24/2024
Locations: GSK Investigational Site, Colorado Springs, Colorado
Conditions: Asthma
Register for Updates
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
NCT04071847
Recruiting
The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.
Gender:
ALL
Ages:
All
Trial Updated:
05/24/2024
Locations: Colorado Neurodiagnostics, Littleton, Colorado
Conditions: Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia, Primary Dystonia, Secondary Dystonia
Register for Updates
Time and Nutrient-Dependent Effects of Aerobic Exercise on Metabolism in Adults (TANDEM Study)
NCT06311487
Recruiting
This study plans to learn more about metabolic responses to aerobic exercise at different times of the day (morning or evening) under fasting versus fed conditions.
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
05/22/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Overweight and Obesity, Healthy
Register for Updates
Swelling Management After Knee Replacement
NCT06095401
Recruiting
To determine if inelastic adjustable compression garment results in improved surgical limb swelling control (bioimpedance assessment - primary outcome) after TKA compared to control (TED hose).
Gender:
ALL
Ages:
Between 50 years and 120 years
Trial Updated:
05/22/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Arthroplasties, Knee Replacement
Register for Updates
Decision Aid for Parents of Infants With UPJO
NCT05900375
Recruiting
Ureteropelvic junction obstruction (UPJO) is the most common etiology of high-grade hydronephrosis, affecting approximately 4,000-10,000 infants annually in the U.S. The goal of surgical treatment of UPJO is to minimize the risk of kidney damage associated with obstruction, which may occur in 30-60% of infants with high-grade hydronephrosis.1-However, the benefit of early surgery compared to observation and potential later surgery to preserve kidney function has not been well-defined. Consequent... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
05/22/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Ureteropelvic Junction Obstruction, Ureteropelvic Junction; Obstruction, Congenital
Register for Updates
HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide
NCT04904588
Recruiting
This is a prospective, multi-center, Phase II study of hematopoietic cell transplantation (HCT) using human leukocyte antigen (HLA)-mismatched unrelated donors (MMUD) for peripheral blood stem cell transplant in adults and bone marrow stem cell transplant in children. Post-transplant cyclophosphamide (PTCy), tacrolimus and mycophenolate mofetil (MMF) will be used for for graft versus host disease (GVHD) prophylaxis. This trial will study how well this treatment works in patients with hematologic... Read More
Gender:
ALL
Ages:
1 year and above
Trial Updated:
05/22/2024
Locations: Colorado Blood Cancer Institute, Denver, Colorado
Conditions: Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Mixed Phenotype Acute Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous Leukemia, Chronic Lymphocytic Leukemia, Lymphoma
Register for Updates