Colorado is currently home to 1810 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
CBD for Individuals at Risk for Alzheimer's Disease
NCT05822362
Recruiting
This is a double-blind, randomized controlled trial designed to test the effects of cannabidiol (CBD) on validated biomarkers of Alzheimer's disease (AD) progression, and behavioral, neurocognitive, and clinical measures, with putative mechanisms of action.
Gender:
ALL
Ages:
Between 55 years and 85 years
Trial Updated:
09/27/2024
Locations: University of Colorado - Anschutz Medical Campus, Aurora, Colorado
Conditions: Mild Cognitive Impairment
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Alcohol Use Disorder and Cannabidiol
NCT05613608
Recruiting
This is a double-blind, placebo-controlled, parallel group study designed to assess the efficacy of full spectrum CBD and broad spectrum CBD, compared to a placebo control (PC), to reduce drinking in participants with alcohol use disorder. If eligible for the study, subjects will be randomized to receive one of the conditions for 12 weeks.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
09/27/2024
Locations: University of Colorado Anschutz, Aurora, Colorado
Conditions: Alcohol Use Disorder
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Pancreas Ultrasound Imaging in type1 Diabetes
NCT05482321
Recruiting
The overall goal of this study is to develop and test a novel method involving ultrasound imaging, in order to detect the development of type 1 diabetes. In this study the investigators will first establish a standard operating procedure for measuring pancreas blood flow speed and volume in the pancreas of human subjects. The investigators will then determine 1) whether these pancreas blood flow factors differ between healthy subjects and those who have recently developed type1 diabetes; and 2)... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/27/2024
Locations: University of Colorado Anschutz, Barbara Davis Center, Aurora, Colorado
Conditions: Type1diabetes, Insulitis, Pancreas Inflamed
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One-4-ALL Initiative
NCT05454969
Recruiting
This study aims to improve health outcomes of individuals and populations, enhance the patient experience, reduce the per capita cost of care, and ensure the well-being of our healthcare providers (quadruple aim). These goals are increasingly difficult to achieve, given the challenges of changes to workflow, staffing shortages, and increased costs brought on by the COVID-19 pandemic. Further, the pandemic brought to light the critical need to transform healthcare access for our racially and cult... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
09/27/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Literacy, Burden, Caregiver, Health Care Utilization
Register for Updates
Reducing Pain and Opioid Use With CBD
NCT05299944
Recruiting
This is a double-blind, placebo-controlled, parallel group study designed to assess the tolerability and efficacy of fsCBD and bsCBD, compared to a placebo control, to reduce opioid use, anxiety, and pain and improve sleep and cognitive function. If eligible for the study, subjects will be randomized to receive one of the conditions for 12 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/27/2024
Locations: University of Colorado - Anschutz Medical Campus, Aurora, Colorado
Conditions: Opioid Use Disorder
Register for Updates
Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry
NCT05052606
Recruiting
INSIGHTS is a registry research study that collects key information on medical history for girls and women with Turner syndrome and the clinical care they receive. This includes genetic tests, imaging, medications, and more for hundreds of patients seen at a number of clinics across the US. In addition to learning a lot about the current state of health for individuals with TS, INSIGHTS serves as an infrastructure to conduct future studies are meaningful to patients and their families.
Gender:
FEMALE
Ages:
All
Trial Updated:
09/27/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Turner Syndrome
Register for Updates
Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease
NCT04902703
Recruiting
A medicine that is FDA-approved for bone marrow stimulation (called sargramostim) will be tested for its safety and efficacy in individuals with mild-to-moderate Alzheimer's disease over a six month treatment period.
Gender:
ALL
Ages:
Between 60 years and 85 years
Trial Updated:
09/27/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Alzheimer Disease
Register for Updates
Slow Wave Sleep As a Biomarker of Rehabilitation-induced Cognitive Improvement in PD
NCT04796506
Recruiting
The purpose of this study is to investigate the effects of exercise rehabilitation on cognition and to evaluate slow wave sleep (SWS) as a biomarker and mediator of response to rehabilitation-induced improvement in cognitive performance among persons with Parkinson's disease (PwP), with the ultimate goal of maximizing rehabilitation efficacy at the individual level (i.e. precision rehabilitation).
Gender:
ALL
Ages:
Between 45 years and 100 years
Trial Updated:
09/27/2024
Locations: University of Colorado, Anschutz Medical Campus, Aurora, Colorado
Conditions: Parkinson Disease
Register for Updates
Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine
NCT04066296
Recruiting
Evaluate the benefit of using liposomal bupivicaine in lumbar laminectomies in terms of length of stay, IV narcotic use, 30-day narcotic use, visual analog score (VAS) and 30-day readmissions
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/27/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Lumbar Spinal Stenosis
Register for Updates
MER3101: MAS-1 Adjuvanted Antigen-specific Immunotherapeutic for Prevention and Treatment of Type 1 Diabetes
NCT03624062
Recruiting
The study is a randomized, double-masked, placebo-controlled, Phase 1 dose-escalation clinical trial. The objective of the trial is to determine if IBC adjuvanted with MAS-1 is safe and will favor tolerogenic pathways to restore immunologic balance and reverse type 1 diabetes (T1D) autoimmunity.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
09/27/2024
Locations: University of Colorado, Denver, Aurora, Colorado
Conditions: Type 1 Diabetes Mellitus
Register for Updates
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies
NCT04561362
Recruiting
This study is a Phase I/II, multicenter, first-in-human, open-label dose-escalation study of BT8009 given as a single agent and in combination with pembrolizumab in participants with advanced solid tumors associated with Nectin-4 expression or in participants with advanced solid tumor malignancies having renal insufficiency. The primary endpoints are: Dose limiting toxicities (Parts A-1 and A-2), Overall response rate per RECIST v1.1 (Parts B1-B7), Safety and tolerability (Parts B-8, B-9 and C),... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: Sarah Cannon Research Institute at HealthONE, Denver, Colorado
Conditions: Advanced Solid Tumor, Urinary Bladder Neoplasm, Triple Negative Breast Neoplasms, Ovarian Neoplasm, Hormone Receptor Positive, HER2-negative Neoplasms, Hormone Receptor Positive, HER2-low Neoplasms, Breast Neoplasms, Non-Small-Cell Lung Neoplasms
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Assessment of the Safety, Tolerability, and Effectiveness of Rifapentine Given Daily for LTBI
NCT03474029
Recruiting
This study is conducted to compare the safety and effectiveness of a novel short 6-week regimen of daily rifapentine (6wP, experimental arm) with a comparator arm of 12-16 weeks of rifamycin-based treatment (standard of care, control arm) of latent M. tuberculosis infection (LTBI). This trial is conducted among persons who are at increased risk of progression to tuberculosis (TB) and require treatment of LTBI. The study will be conducted in low, medium and high TB incidence settings that have t... Read More
Gender:
ALL
Ages:
12 years and above
Trial Updated:
09/25/2024
Locations: Denver Health and Hospital Authority, Denver, Colorado
Conditions: Latent Tuberculosis
Register for Updates