Colorado is currently home to 1800 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction
NCT01526681
Recruiting
This study is a registry of general use of Avance Nerve Graft and is intended to evaluate the uses, response rates, and safety of Avance Nerve Graft in the real-life clinical setting. Optional addendums 1 and 2 included in the protocol are intended to establish comparative groups and focused subgroups within the registry.
Gender:
ALL
Ages:
All
Trial Updated:
07/25/2024
Locations: Sensation-NOW: University of Colorado School of Medicine, Aurora, Colorado
Conditions: Peripheral Nerve Injuries
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Relationships Between Physical Activity and Different Measures of Fatigue in Cancer Survivors
NCT05073848
Recruiting
This is an investigation of possible relationships between daily physical activity (PA) and different measurements of fatigue in cancer survivors participating in a cancer exercise program.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: University of Colorado Cancer Center, Aurora, Colorado
Conditions: Cancer Remission
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Adjustable Continence Therapy (ACT) for the Treatment of Female SUI
NCT04248283
Recruiting
A prospective, single arm, non-randomized, multicenter, prospective case-series trial. The purpose of this trial is to demonstrate the safety and effectiveness of using the Adjustable Continence Therapy (ACT) to provide a clinically relevant improvement in stress urinary incontinence.
Gender:
FEMALE
Ages:
22 years and above
Trial Updated:
07/22/2024
Locations: University of Colorado, Denver, Colorado
Conditions: Urinary Incontinence, Urinary Incontinence,Stress
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Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation
NCT06518746
Recruiting
The "Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation" study is open to a subset of patients with disorders of sex development (DSD) which is associated with the risk of malignancy and a high risk of infertility or sterility. For these patients, experimental gonadal tissue cryopreservation is the only fertility preservation option available. The overall objective of this study is to determine the safety and efficacy of gonadal tissue cryopreservation as a method of preservin... Read More
Gender:
ALL
Ages:
30 years and below
Trial Updated:
07/18/2024
Locations: University of Colorado, Aurora, Colorado
Conditions: Ovarian Cancer
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Effects of a Microalgae Extract Dietary Supplement on Gut Health, Anxiety, and Immune Function
NCT06425094
Recruiting
This study will be conducted to determine the effect of daily Tetrasol consumption in supporting gut health using assessments of gastrointestinal symptoms (GSRS) and bowel habits (BSS) as primary outcome measures. The investigators also intend to explore fecal and blood biomarkers of intestinal permeability/function, determination of anxiety and stress levels through both validated assessments and saliva and blood biomarkers, establishment of intervention safety and tolerability through comprehe... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/18/2024
Locations: Food and Nutrition Clinical Research Lab(FNCRL), Colorado State University, Fort Collins, Colorado
Conditions: Gastrointestinal Problem, Anxiety, Stress, Gastrointestinal Symptoms
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MYLUNG Consortium Part 3: Observational Study
NCT05885698
Recruiting
This longitudinal study looks to quantify the testing timeline, operational barriers, and outcomes of biomarker-guided therapy in a large, community-based, and largely unselected patient population with early stage and advanced stage, treatment-naive non-small cell lung cancer, whether squamous or non-squamous.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2024
Locations: Rocky Mountain Cancer Center, Denver, Colorado
Conditions: Carcinoma, Non-Small-Cell Lung
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A Multilevel Intervention to Improve Adherence to Childhood Cancer Survivorship
NCT05448560
Recruiting
More than 80% of childhood cancer survivors develop serious or life-threatening late effects after cancer therapy, but \<20% receive recommended survivorship care offered at cancer center survivorship clinics. In a shared care model, the investigators propose to investigate an innovative multi-level intervention consisting of: 1) patient survivorship education via telehealth with the cancer center, 2) ongoing patient-tailored education program within the electronic health record patient portal,... Read More
Gender:
ALL
Ages:
2 years and above
Trial Updated:
07/17/2024
Locations: Children's Hospital Colorado, Denver, Colorado
Conditions: Childhood Cancer, Survivorship, Health Care Utilization, Health Knowledge, Attitudes, Practice, Adherence, Patient
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Restricted or Liberal Antibiotics After Appendectomy - Denver Health
NCT05002829
Recruiting
The purpose of this study is to see if decreasing the amount of antibiotics after appendicitis surgery can decrease the risk of adverse effects associated with antibiotics while at the same time ensuring participant safety.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2024
Locations: Denver Health and Hospital Authority, Denver, Colorado
Conditions: Appendicitis
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Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors
NCT05997056
Recruiting
A Phase 2 multi-center, open-label, single arm study of nab-sirolimus in patients with well-differentiated neuroendocrine tumors (NETs) of the gastrointestinal tract, lung, or pancreas who have not received prior treatment with mTOR inhibitors
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/15/2024
Locations: Rocky Mountain Cancer Centers, Denver, Colorado
Conditions: Neuroendocrine Tumors, NET, Pancreatic Neuroendocrine Tumor, Gastrointestinal Neuroendocrine Tumor, Pulmonary Neuroendocrine Tumor
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A Phase 2 Study of VLX-1005 Versus Placebo in Suspected Heparin Induced Thrombocytopenia
NCT05785819
Recruiting
The purpose of this study is to evaluate the efficacy and safety of VLX-1005, a 12-lipoxygenase (12-LOX) enzyme inhibitor in treating heparin induced thrombocytopenia (HIT). Participants with suspected HIT will receive the usual standard of care, and will be assigned randomly to either VLX-1005 or placebo treatment. The study will measure important outcomes including platelet count, stroke, pulmonary embolus (clot to the lungs) and bleeding.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2024
Locations: University of Colorado, Aurora, Colorado
Conditions: Thrombocytopenia, Immune, Heparin Induced Thrombocytopenia
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Pediatric Medication Therapy Management Trial
NCT05761847
Recruiting
The purpose of this study is to evaluate whether an intervention called Pediatric Medication Therapy Management (pMTM) improves the identification and management of medication-related problems among children with medical complexity and polypharmacy.
Gender:
ALL
Ages:
Between 2 years and 18 years
Trial Updated:
07/12/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Child, Only, Disabilities Multiple, Medication Interaction, Medication Compliance, Medication Administered in Error
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KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis
NCT05938725
Recruiting
A Study of Anti-CD19 Chimeric Antigen Receptor T Cell Therapy for Subjects With Refractory Lupus Nephritis
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2024
Locations: University of Colorado, Denver, Colorado
Conditions: Lupus Nephritis, Lupus Nephritis - World Health Organization (WHO) Class III, Lupus Nephritis - WHO Class IV
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