There are currently 243 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
Charcot-Marie-Tooth Disease (CMT) Biological Sample Collection for IPSC Generation and Biobanking
NCT06203093
Recruiting
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate Charcot-Marie-Tooth disease research and drug development by using cells from the body (such as skin or blood cells) to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, and/or store the samples for future use. Through this research, researchers hope to identify future treatments or even cures for Charcot-Marie-Tooth disease.
Gender:
ALL
Ages:
5 years and above
Trial Updated:
02/27/2025
Locations: New York Stem Cell Foundation Research Institute, New York, New York
Conditions: Charcot-Marie-Tooth Disease, Healthy
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A Study of LY4005130 in Healthy Participants
NCT06690996
Recruiting
The purpose of this study is to evaluate how well LY4005130 is tolerated and what side effects may occur in healthy participants. The study drug will be administered either subcutaneously (SC) (under the skin) or intravenously (IV) (into a vein in the arm). Blood tests will be performed to check how much LY4005130 gets into the bloodstream and how long it takes the body to eliminate it. Part A for the single-ascending doses (SAD) of the study will last about 12 weeks with 9 visits. Part B for t... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/27/2025
Locations: Fortrea Clinical Research Unit, Dallas, Texas
Conditions: Healthy
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A First-In-Human Study of LY3985297 in Healthy Participants
NCT06395012
Recruiting
The main purpose of this study is to see if LY3985297, the study drug, is safe and well-tolerated when given as a single dose or as multiple doses either through an intravenous (into a vein) or a subcutaneous (under the skin) injection in healthy participants. Study will also evaluate how much of the study drug LY3985297 gets into the blood stream and how long it takes the body to remove it. The study is conducted in two parts (part A and B), each part has a separate treatment cohort. The stud... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
02/27/2025
Locations: CenExel ACT, Anaheim, California +1 locations
Conditions: Healthy
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A Study of LY3537031 in Overweight, Obese, and Healthy Participants
NCT06606106
Recruiting
This is a 3-part study that includes a Part A, Part B, and Part C. Part A will study the safety and tolerability of the study drug known as LY3537031 in participants who are overweight and obese. Part B and Part C will study the safety and tolerability of LY3537031 in healthy participants. Part C will contain only Japanese and Chinese healthy participants. Blood tests will be performed to check how much LY3537031 gets into the bloodstream and how long it takes the body to eliminate it. Body wei... Read More
Gender:
ALL
Ages:
Between 22 years and 65 years
Trial Updated:
02/27/2025
Locations: Collaborative Neuroscience Research, LLC, Los Alamitos, California +4 locations
Conditions: Healthy, Obesity
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Drug Discovery for Parkinson's with Mutations in the GBA Gene
NCT05536388
Recruiting
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate Parkinson's disease research and drug development by using cells from the body (such as skin or blood cells) to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, and/or store the samples for future use. Through this research, researchers hope to identify future treatments or even cures for Parkinson's disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2025
Locations: The New York Stem Cell Foundation Research Institute, New York, New York
Conditions: Parkinson Disease, Gaucher Disease, Healthy, GBA Gene Mutation
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A Study of LY3971297 in Healthy Participants and Participants With Obesity and Hypertension
NCT06148272
Recruiting
The purpose of this study is to measure side effects of LY3971297 injection administered under the skin in healthy participants and obese participants with high blood pressure (BP). Blood tests will be performed to check how much LY3971297 gets into the bloodstream and how long it takes the body to eliminate it. This is a 7-part study. The study duration will be approximately 60 days for Parts A and F, and approximately 90 days for Parts B, C, D, E, and G.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/27/2025
Locations: CenExel ACT, Anaheim, California +2 locations
Conditions: Healthy, Obesity, Hypertension
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Spectral Characteristics of Memory Transformation
NCT05946616
Recruiting
Sometimes, it is necessary to re-learn a previously learned movement behavior, for example, a bad posture during the golf drive or while playing the piano. Unlearning or relearning an intensively trained behavior is particularly important if the behavior is hampering recovery, for example, in chronic pain or after a stroke. With this pilot study, the brain mechanisms that control the change of pre-existing stable memories of a motor skill will be tested with electroencephalography (EEG). Non-inv... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Healthy
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Efficacy of Respiratory Protection Against the Effects of Wood Smoke Exposure in Young Healthy Adults (MASKON)
NCT06066749
Recruiting
Purpose: This study is designed to test whether the gaseous fraction of woodsmoke, volatile organic compounds, produce acute cardiac, respiratory, and systemic inflammatory health effects after controlled exposure to woodsmoke in health, young volunteers. Participants: Approximately fifty, 18-35 year-old healthy volunteers to complete the study. Procedure: After consenting to participate in the study, participants will undergo two exposures to approximately 500 μg/m3 woodsmoke. The two exposur... Read More
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
02/25/2025
Locations: U.S. Environmental Protection Agency Human Studies Facility, Chapel Hill, North Carolina
Conditions: Healthy
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A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers
NCT06667661
Recruiting
The goal of this clinical trial is to evaluate whether a home-based mHealth intervention can improve adherence to the 24-Hour Movement Guidelines in preschool-aged children (3-4 years old) who currently meet 0 or 1 of the guidelines for physical activity, sedentary behavior, and sleep. The main questions it aims to answer are: * Can the intervention increase the proportion of children meeting all three 24-Hour Movement Guidelines (physical activity, screen-time, and sleep)? * Is the interventio... Read More
Gender:
ALL
Ages:
Between 3 years and 4 years
Trial Updated:
02/25/2025
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Healthy, 24-Hour Movement Guidelines, Feasibility Studies, Sleep, Physical Activity, Screen Time, Sedentary Behaviors, Motor Skills, Cognition, Parent-Child Relations, Mobile Application, Health Education, Child Development
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Early Detection of Vascular Dysfunction Using Biomarkers From Lagrangian Carotid Strain Imaging
NCT04632485
Recruiting
The purpose of this research is assess imaging and identification of soft plaque that undergoes large deformations or strain will identify plaque vulnerable to rupture which could lead to 'silent strokes'. Validation of current study results with MRI will foster use of real-time ultrasound (US) strain imaging and strain indices as a screening tool for identifying normal human participants susceptible to increased vascular aging and developing plaque prone to rupture or micro-embolization. Curre... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
02/24/2025
Locations: Department of Medical Physics, University of Wisconsin, Madison, Wisconsin
Conditions: Healthy, Carotid Artery Diseases
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Influence of Brain Oscillation-Dependent TMS on Motor Function
NCT03288220
Recruiting
Background: When people have a stroke, they often have difficulty moving their arms and hands. Transcranial magnetic stimulation (TMS) can improve how well people with and without stroke can move their arms and hands. But the effects of TMS are minor, and it doesn t work for everyone. Researchers want to study how to time brain stimulation so that the effects are more consistent. Objective: To understand how the brain responds to transcranial magnetic stimulation so that treatments for people... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/22/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy, Stroke, Normal Physiology, Aging
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Craniofacial Dimensions as Determinants of the Fitted Performance of Common Face Masks (FACEFIT 2.0)
NCT06425588
Recruiting
This study examines the role of craniofacial dimensions and self-evaluation thereof in the protection afforded by masks commonly worn by the public as protection against aerosol contaminants. The effectiveness of instructions for self-evaluation of craniofacial dimensions will be tested against standard digital and manual craniometric methods. Approximately 500 (18-70 year old) subjects. After consenting to participate in the study, subjects will use a short self-assessment questionnaire to me... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
02/21/2025
Locations: U.S. Environmental Protection Agency Human Studies Facility, Chapel Hill, North Carolina
Conditions: Healthy
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