There are currently 241 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
A Study to Learn How Different Amounts of the Study Medicine Called PF-08049820 Are Tolerated and Act in the Body in Healthy Adults
Recruiting
The purpose of this study is to learn about the safety of the study medicine called PF-08049820 in healthy adults. The study will also see: * how the body processes the study medicine and * if food affects the amount of study medicine in the blood. The study medicine is developed for the treatment of moderate to severe atopic dermatitis, also known as eczema. People with this condition may have severe itching and rashes on the skin. The study is seeking participants who: 1. Are males or fema... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/09/2025
Locations: Pfizer Clinical Research Unit - New Haven, New Haven, Connecticut
Conditions: Healthy
A Clinical Study of MK-1084 in Participants With Renal Impairment (MK-1084-010)
Recruiting
The goal of this study is to learn what happens to MK-1084 levels in a person's body over time. Researchers will measure what happens to MK-1084 levels in the body when it is given to people with moderate or severe renal impairment (RI) (meaning the kidneys do not work properly) as compared to people who are in good health. Researchers also want to learn about the safety of MK-1084 when it is given to people with RI and if people with RI can tolerate it.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
06/05/2025
Locations: Orlando Clinical Research Center ( Site 0002), Orlando, Florida +1 locations
Conditions: Healthy, Renal Impairment
Neural Control of Kidney Blood Flow During Exercise in African American Adults
Recruiting
The goal of this clinical trials is to learn if healthy young African American (AA) adults have a larger change in their kidney blood flow during exercise compared to White (W) adults. The main questions that this study aims to answer are: * Do healthy young AA adults have a larger decrease in kidney blood flow during exercise compared to W adults? * Do healthy young AA adults have a larger decrease in kidney blood flow during other types of stress compared to W adults? During two visits in th... Read More
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
06/04/2025
Locations: University of Massachusetts Boston, Boston, Massachusetts
Conditions: Healthy
A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults
Recruiting
The objective of the study is to use neurological techniques to obtain quantitative measurements of nervous system control of skeletal muscle activity in adults aged 60-85 who are either long-term resistance exercisers or who are untrained.
Gender:
ALL
Ages:
Between 60 years and 85 years
Trial Updated:
06/04/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy, Insulin Resistance
Skin Microbial Ecology in Atopic Dermatitis
Recruiting
Everybody's skin has bacteria that normally lives on it. Previous research has shown that people with eczema (or atopic dermatitis \[AD\]) have much higher concentrations of a certain bacteria (S. aureus), especially when their disease is active but little is known about the role that this bacteria plays in psoriasis (i.e. disease severity, biomarkers and skin barrier function). The overarching purpose of this longitudinal study is to understand how the abundance of skin S. aureus (and several c... Read More
Gender:
ALL
Ages:
13 years and above
Trial Updated:
06/02/2025
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Atopic Dermatitis, Psoriasis, Healthy
Characterization of Gastric Evoked Potentials
Recruiting
This is an exploratory study that will determine and standardize how best to record gastric evoked potentials (GEPs) elicited by a non-invasive method of brain stimulation (Transcranial Magnetic Stimulation, TMS), by optimizing the TMS parameters and cortical sites necessary to evoke GEPs.
Gender:
ALL
Ages:
Between 21 years and 60 years
Trial Updated:
06/02/2025
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Healthy
A Study of Food Effect and Esomeprazole on LY4064809 in Healthy Adult Participants
Recruiting
The purpose of this study is to evaluate the safety and effect of food on LY4064809 and the safety and effect of stomach changes by a proton pump inhibitor (PPI) esomeprazole, under fasted conditions in healthy adult participants. Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
06/02/2025
Locations: Pharmaron Clinical Pharmacology Center Inc, Baltimore, Maryland
Conditions: Healthy
Multifocal HD-tDCS and Motor Function
Recruiting
The purpose of this study is to understand how the brain controls movement and how Non-invasive Brain Stimulation (NIBS) with a technique called High-density transcranial direct current stimulation (HD-tDCS) can alter brain processes to improve behavior. Participants in this study will be randomized to either HD-tDCS with standard intervention or personalized dose-controlled multifocal network-targeted HD-tDCS. The hypothesis is that dexterous hand function will improve after a standard HD-tDCS... Read More
Gender:
ALL
Ages:
Between 65 years and 85 years
Trial Updated:
05/30/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Healthy
Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy Volunteers
Recruiting
Background: PDE4D is a protein in the body that plays a role in thinking and depression. This protein may play a major role in disorders such as Alzheimer disease or major depressive disorder. To learn more about these disorders, researchers want to be able to detect levels of PDE4D in the brain. 11C-JMJ-129 is a new radiotracer (a radioactive substance that highlights parts of the body during imaging scans) that was developed to attach only to PDE4D. Objective: To test the new radiotracer 11... Read More
Gender:
ALL
Ages:
Between 18 years and 101 years
Trial Updated:
05/30/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy
Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid Infusion
Recruiting
This study is being done to better understand how amino acids alter the release of glucagon and insulin compared to glucose alone in health and disease.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
05/30/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy, Type 2 Diabetes, Obesity
SV2A Density Cannabis Use Disorder
Recruiting
The main purpose of this study is to determine whether hippocampal synaptic vesicle density estimated by hippocampal \[11C\]APP-311/\[11C\]UCB-J binding in individuals diagnosed with cannabis use disorder (CUDs) improves with at least 4 weeks of confirmed abstinence from cannabis, in comparison to healthy controls (HCs). Furthermore, any change in synaptic vesicle density will be placed in functional context by measuring verbal memory, which is sensitive to hippocampal function, before and after... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/29/2025
Locations: Yale University School of Medicine, New Haven, Connecticut
Conditions: Cannabis Use Disorder, Healthy
Cell Free DNA in Cardiac Sarcoidosis
Recruiting
Sarcoidosis is a multisystem granulomatous disease of unknown cause that can affect any organ in the body, including the heart. Granulomatous myocarditis can lead to ventricular dysfunction and ventricular arrhythmias causing significant morbidity and mortality. Immunosuppressive therapy (IST) has been shown to reverse active myocarditis and preserve left ventricular (LV) function and in some cases improve LV function. In addition, IST can suppress arrhythmias that develop due to active myocardi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/29/2025
Locations: University of Iowa, Iowa City, Iowa +1 locations
Conditions: Sarcoidosis With Myocarditis, Sarcoidosis, Healthy, ST Elevation Myocardial Infarction