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Massachusetts Paid Clinical Trials
A listing of 3148 clinical trials in Massachusetts actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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Clinical Trial Phase
Massachusetts is currently home to 3148 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Boston, Worcester, Springfield and Burlington. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Studying an Investigational Virus Vaccine
Recruiting
The main objectives of this study are to assess the safety and effectiveness of an investigational vaccine aimed at preventing norovirus, commonly known as the stomach flu. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Healthy
Interested in vaccine studies
All Conditions
Preventative Trials
Featured Trial
Type 2 Diabetes Clinical Trial
Recruiting
Can changing your breakfast improve your type 2 diabetes? If you have an HbA1C of 7.0% or higher, you are invited to participate in an online study at the University of Michigan.
Conditions:
Type 2 Diabetes
Diabetes Mellitus Type 2 in Obese
Diabetes Type Two
Type 2 Diabetes Mellitus
Diabete Type 2
Featured Trial
Evaluating an Investigational Treatment for Hidradenitis Suppurativa
Recruiting
The main objectives of this Phase 2 study are to evaluate the safety and effectiveness of an investigational medication in adults with moderate to severe hidradenitis suppurativa (HS), a chronic skin condition. Participants will be randomly assigned to receive the investigational treatment or a placebo. Should you express interest, the research site will contact you directly to provide further details and address any questions you may have about study requirements, risks/benefits, and compensation.
Conditions:
All Conditions
Hidradenitis suppurativa (Skin disorder)
Dermatology
Featured Trial
Crohn's Disease Clinical Study
Recruiting
Help us study a potential new way to treat Crohn's disease. We are seeking adults living with Crohn's disease to join our latest clinical trial to help us learn more. Eligible participants will receive study-related treatment, assessments, and care at no cost. You will also receive reimbursement for travel while participating. Health insurance is not required to take part.
Conditions:
Crohn's Disease
Crohn Disease
Crohns Disease
Crohn's Disease (CD)
Crohn Colitis
Effect of Physical Activity Pattern on Cardiometabolic Health
Recruiting
The goal of this study is to understand the interaction between the circadian system and physical activity.
Participants will:
* complete 2 inpatient stays
* perform moderate exercise
* be provided with identical meals
* have frequent blood draws
* provide urine and saliva samples
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
11/22/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Life Style
A Study of ZN-c3 in Patients With Ovarian Cancer
Recruiting
This is a Phase 1b open-label, multicenter study, evaluating the safety, tolerability, preliminary clinical activity, pharmacokinetics (PK), and pharmacodynamics of ZN-c3 in combination with other drugs.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: Site 0104, Boston, Massachusetts
Conditions: Solid Tumor, Epithelial Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis
Recruiting
The goal of this study is to discover new genetic causes of infantile epilepsies and evaluate the impact of these discoveries on infants with epilepsy and their families.
Gender:
ALL
Ages:
All
Trial Updated:
11/21/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Neonatal Epilepsy, Infantile Epilepsy
Investigating the Effects of Tube Feeds on Glycemia and Sleep in Adults With Cystic Fibrosis-Related Diabetes
Recruiting
The goal of this at-home, remote study is to understand how tube feeding affects blood sugars and sleep in adults living with Cystic Fibrosis Related Diabetes (CFRD).
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
11/21/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Cystic Fibrosis Related Diabetes, Hyperglycaemia, Insomnia, Cardiometabolic Diseases, Circadian Rhythm Disorders
A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)
Recruiting
This is a Phase 1/2 multicenter, open-label, single dose trial of SP-101 investigational gene therapy in adults with CF who are ineligible for or intolerant to CFTR modulator therapy.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/21/2024
Locations: Boston Children's Hospital, Brigham & Women's Hospital, Boston, Massachusetts
Conditions: Cystic Fibrosis
Mobile Application to Improve Health-Related Outcomes in Patients With Advanced Lung Cancer
Recruiting
Multi-site randomized trial of the THRIVE digital health application versus usual care to evaluate the effect of THRIVE on quality of life (QOL), physical and psychological symptoms, coping, and self-efficacy in 250 patients with newly diagnosed advanced lung cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Lung Cancer
A Text- and Audio-based Intervention to Promote Physical Activity in Midlife
Recruiting
This is a randomized, controlled pilot trial (N=30) to examine the feasibility, acceptability, and preliminary efficacy of the Move with Meaning program, an 8- week, text message- and audio-based intervention to promote physical activity in midlife adults.
Gender:
ALL
Ages:
Between 45 years and 64 years
Trial Updated:
11/21/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Middle Aged
Vagus Nerve Stimulation(VNS) As Treatment For Fibromyalgia Patients
Recruiting
Fibromyalgia (FM) is a syndrome with clinical symptoms involving multiple systems. The efficacy of current treatments is inadequate, and more alternative modalities are needed for the management of FM patients. The parasympathetic vagus nerve innervates and integrates sensory, motor, and autonomic systems and has been suggested to play a role in pain modulation. The role of vagus nerve stimulation (VNS) as a treatment option for FM patients is yet to be investigated. The investigators propose to... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/21/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Fibromyalgia
DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors
Recruiting
This is a multicenter, open-label, Phase 1 study to assess the effects of DCSZ11, an anti-CD93 monoclonal antibody, as a monotherapy and in combination in patients with advanced or metastatic solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Advanced or Metastatic Solid Tumors
Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells
Recruiting
The proposed Conventional Cohort Expansion Study involves the use of Mesenchymal Stromal Cells (MSCs) are derived from the bone marrow. We previously studied the safety of subconjunctival injection of allogeneic bone marrow-derived MSCs in patients with nonhealing epitheliopathy (IRB Protocol 2020-0334). In the present study, we want to study the efficacy of this treatment on chronic epitheliopathies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Mass Eye and Ear Infirmary, Boston, Massachusetts
Conditions: Corneal Ulcer
Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure
Recruiting
The purpose of this study is to assess whether 480 mg/day magnesium glycinate supplementation for 12 weeks lowers blood pressure.
Gender:
ALL
Ages:
Between 30 years and 74 years
Trial Updated:
11/21/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Blood Pressure
Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)
Recruiting
To evaluate the safety and efficacy of intravenous (IV) administration of bone marrow mesenchymal stem cell derived extracellular vesicles (EVs), ExoFlo, versus placebo for the treatment of hospitalized patients with moderate-to-severe Acute Respiratory Distress Syndrome (ARDS).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/21/2024
Locations: Direct Biologics Investigational Site, Boston, Massachusetts
Conditions: Acute Respiratory Distress Syndrome, ARDS