Massachusetts is currently home to 3175 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Boston, Worcester, Springfield and Burlington. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effects of MIB-626 With and Without A High-Intensity Multi-Dimensional Exercise Training Program
NCT05878119
Recruiting
A single-center, randomized, placebo-controlled study in community dwelling, healthy, regularly exercising, highly physically fit men and women, 19 to 40 years. Eligible participants will be randomized to receive either 1000 mg NMN or placebo twice daily for 10 weeks.
Gender:
ALL
Ages:
Between 19 years and 40 years
Trial Updated:
11/01/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Healthy
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Lenvatinib in Locally Advanced Invasive Thyroid Cancer
NCT04321954
Recruiting
This research is being done to evaluate the safety and efficacy of neoadjuvant lenvatinib on surgical outcomes of patients with invasive extrathyroidal differentiated thyroid cancer (DTC). This research study involves a study drug called lenvatinib
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/01/2023
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Conditions: Differentiated Thyroid Cancer, Advanced Cancer
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A Clinical Trial of Pulsed-dye Laser Versus Timolol Topical Solution Versus Observation on the Growth of Hemangioma in Newborn
NCT01873131
Recruiting
The purpose of this study is to find out if pulsed dye laser treatment or timolol maleate 0.5% gel can help infants who have a hemangioma. The investigators also want to find out if pulsed dye laser treatment and timolol maleate 0.5% gel are safe to use without causing too many side effects. Hemangioma is a common type of birthmark. These birthmarks happen when many new blood vessels grow in a specific area on the skin. Blood vessels are tiny tubes that carry blood through the body. No one know... Read More
Gender:
ALL
Ages:
3 months and below
Trial Updated:
11/01/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Hemangioma
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COmbination Therapy With Baloxavir and Oseltamivir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)
NCT04327791
Recruiting
This is a randomized, double-blind, placebo-controlled Phase 2-like, investigator-directed trial of hospitalized patients with laboratory confirmed influenza. Eligible and consented patients will be randomly assigned, in a 1:1 ratio, to one of two groups: Group 1, the combination treatment group (oseltamivir and baloxavir); Group 2, the standard treatment group (oseltamivir and placebo).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/27/2023
Locations: Baystate Medical Center, Springfield, Massachusetts
Conditions: Influenza
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Clinical Study to Evaluate Different Energy-based Devices for Aesthetic Treatments.
NCT06111482
Recruiting
The goal of the energy-based devices used in this study is to evaluate their safety and performance to treat unwanted dermatologic conditions.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
10/26/2023
Locations: Cynosure, Westford, Massachusetts
Conditions: Dermatologic Conditions
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An Ethical Approach to Detecting Covert Consciousness
NCT05010265
Recruiting
This study aims to develop an ethical approach to developing and deploying novel neurotechnologies to aid in the detection of consciousness and prediction of recovery after brain injury.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/26/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Disorder of Consciousness
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MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction
NCT05673005
Recruiting
The investigators are doing this research to evaluate the efficacy and safety of topical MED3000 therapy in men with persistent erectile dysfunction 1.5 to 4 years following radical prostatectomy surgery.
Gender:
ALL
Ages:
Between 40 years and 70 years
Trial Updated:
10/25/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Erectile Dysfunction Following Radical Prostatectomy
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INF108F in Infants With Food Protein Induced Proctocolitis
NCT05793112
Recruiting
Single-center, randomized, double-blind, placebo-controlled trail evaluating INF108F in breastfed infants with FPIAP
Gender:
ALL
Ages:
Between 1 day and 90 days
Trial Updated:
10/24/2023
Locations: Newton Wellesley Hospital, Newton, Massachusetts
Conditions: Infant Development, Gut Microbiome, Food Protein Induced Allergic Proctocolitis
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A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB
NCT05183646
Recruiting
DMX-200 (repagermanium) is a C-C chemokine receptor type 2 (CCR2) inhibitor that, when administered concurrently with an ARB, is designed to inhibit recruitment of monocytes implicated in the inflammatory chemokine environment of chronic disease. The purpose of this pivotal randomized double-blind study is to investigate the efficacy and safety of DMX-200 120 mg twice daily (BID) compared with placebo over a treatment period of 104 weeks in adult patients with FSGS who are being treated with an... Read More
Gender:
ALL
Ages:
Between 12 years and 80 years
Trial Updated:
10/24/2023
Locations: ACTION3 Investigational Site 21, Springfield, Massachusetts
Conditions: FSGS
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Triage Survey for Neurology Research Eligibility
NCT06104852
Recruiting
TRIAGE-Neuro is a survey study designed to assess potential participants' eligibility to screen for industry-sponsored neurology clinical trials.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/23/2023
Locations: Copley Clinical, Boston, Massachusetts
Conditions: Alzheimer Disease
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A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest
NCT05899361
Recruiting
This research study is a pilot clinical trial, which hypothesizes that the combination of electromagnetic tracking in conjunction with laparoscope imaging and ultrasound probe imaging will aid in reducing the complexity of both laparoscopic lymphadenectomy and/or organ removal in patients with a confirmed diagnosis of cancer in urologic regions of interest (Bladder, Prostate, Testicular, Kidney, Urethral, and Penis), by resulting in better visualization and more accurate localization of certain... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/23/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Urologic Cancer, Urologic Neoplasms, Bladder Cancer, Prostate Cancer, Testicular Cancer, Kidney Cancer, Urethral Cancer, Penile Cancer
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Urologic Lymphadenectomy in AMIGO
NCT05132283
Recruiting
This research study involves the use of two navigation systems, the 3D Slicer-based navigation system, and the Siemens Monaco systems, to simplify the complexity of image-guided lymphadenectomy procedures (surgery to remove one or more lymph nodes) in patients with urological cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/23/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Urologic Cancer, Lymph Node Metastasis
Register for Updates