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Massachusetts Paid Clinical Trials
A listing of 3376 clinical trials in Massachusetts actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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Clinical Trial Phase
Massachusetts is currently home to 3376 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Boston, Worcester, Springfield and Burlington. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Featured Trial
Major Depressive Disorder Clinical Study
Recruiting
Is depression weighing you down? Local major depressive disorder clinical studies are now enrolling participants in the area. Participating in research studies helps contribute to the advancement of future medicine and treatment options. There is no obligation to take part and health insurance is not required.
Conditions:
Major Depressive Disorder
Major Depression
Major Depressive Episode
Major Depressive Disorder (MDD)
Major Depressive Disorders
Featured Trial
Hyperacusis Activities Treatment-Online Study
Recruiting
Are you experiencing hyperacusis? If so, we are recruiting adults with hyperacusis to complete a clinical trial supported by the National Institutes of Health. The study involves participating in a remote counseling program and sound therapy trial for hyperacusis, Hyperacusis Activities Treatment-Online.
Conditions:
Hyperacusis
Tinnitus
Hearing Loss
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Exploration of Blood Flow Regulation to Bone in Humans
Recruiting
Without blood flow, bone cannot maintain its integrity. Bone blood flow responds to various local and systemic factors, however, bone perfusion in humans remains relatively unstudied. The investigators will study key mechanisms that regulate bone perfusion in able-bodied and contrast responses to those with spinal cord injury (SCI). SCI is a model of chronic reduced loading with loss of sympathetic regulation. In tibial cortical bone, the investigators will: 1) determine the impact of compressiv... Read More
Gender:
All
Ages:
Between 18 years and 40 years
Trial Updated:
02/21/2023
Locations: Spaulding Rehabilitation Cambridge/ Cardiovascular Laboratory, Cambridge, Massachusetts
Conditions: Bone Blood Flow Regulation
SEAM Trial: Sutureless End to End Anastomosis by Magnetic Compression
Recruiting
The objectives of this study are to determine the safety and effectiveness of the SFM Anastomosis Device when used to create a small bowel anastomosis for patients undergoing ileostomy reversal as compared with a propensity-matched historic control group of patients who underwent ileostomy reversal using a conventional closure technique (sutures or stapler).
Gender:
All
Ages:
18 years and above
Trial Updated:
02/19/2023
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Retraction of Ileostomy
Telehealth Intervention Strategies for WIC (THIS-WIC)- Michigan
Recruiting
With funding through the United States Department of Agriculture (USDA) and Tufts University's Telehealth Intervention Strategies for WIC (THIS-WIC), Michigan's (MI) WIC department will pilot telehealth opportunities as a means of delivering services to WIC Clients. This video conferencing pilot looks to improve and/or remove barriers. Implementing a pilot program in select local agencies to utilize technology would allow clients to connect with a WIC Registered Dietitian (RD) or an Internationa... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/16/2023
Locations: Tufts University, Boston, Massachusetts
Conditions: Telehealth, Nutrition Education, Breast Feeding, Dietary Intake, WIC
Efficacy of Suvorexant in the Treatment of Insomnia in Midlife Women With Pre-Diabetes
Recruiting
The aim of this study is to determine if suvorexant can help treat the severity of insomnia in midlife women who are pre-diabetic.
Gender:
Female
Ages:
Between 40 years and 65 years
Trial Updated:
02/16/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Evaluation of UDP-glucose as a Urinary Biomarker for Early Detection of Cardiac Surgery-associated Pediatric Acute Kidney Injury
Recruiting
Acute kidney injury (AKI) is common in children after cardiac surgery with a reported incidence of 20-40%. Pediatric AKI has been found to be associated with important short and long-term adverse outcomes.
A major challenge to management of AKI after cardiac surgery and cardiopulmonary bypass is the lack of early diagnostic markers. Current diagnostic criteria for AKI in children relies exclusively on elevation of serum creatinine concentration and oliguria. Both of these markers lack sensitivi... Read More
Gender:
All
Ages:
8 years and below
Trial Updated:
02/16/2023
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Acute Kidney Injury
Dual BET and CBP/p300 Inhibitor in Patients With Targeted Advanced Solid Tumors
Recruiting
A Phase 1, first-in-human study of EP31670, a dual BET and CBP/p300 inhibitor in patients with targeted advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/15/2023
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Castrate Resistant Prostate Cancer, NUT Carcinoma
A Study of Therapeutic Iobenguane (131-I) and Vorinostat for Recurrent or Progressive High-Risk Neuroblastoma Subjects
Recruiting
The purpose of this study is to evaluate the efficacy and safety of 131I-MIBG in combination with Vorinostat in patients with Recurrent or Progressive neuroblastoma
Gender:
All
Ages:
1 year and above
Trial Updated:
02/15/2023
Locations: Dana-Farber Cancer Institute, Boston, Massachusetts
Conditions: Neuroblastoma, Neuroectodermal Tumors, Neoplasms
Endoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease
Recruiting
The goal of this observation study is to assess whether endoscopic ultrasound shear wave elastography (EUS-SWE) may be a useful tool for liver fibrosis screening in patients with elevated body mass index and non alcoholic fatty liver disease as compared to other non-invasive screening modalities, which have traditionally had less accurate results in this population.
The main questions it aims to answer are:
Determine accuracy of EUS-SWE for liver fibrosis screening compared to other non-invasi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/13/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis, Obesity
Rate of Bony Fusion Using NanoBone® Synthetic Bone Graft Versus Local Autologous Bone Graft.
Recruiting
The objectives of this longitudinal study are to assess and measure fusion status (fused or not fused) and rate of bony fusion using NanoBone® Synthetic Bone Graft in patients requiring one to two level lumbar posterolateral fusion procedures with or without commercially available rigid spinal instrumentation. Our hypothesis is that the Nanobone synthetic bone graft will be as effective at creating a fusion in the lumbar spine as compared with a local bone graft. Each subject will serve as their... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
02/10/2023
Locations: UMass Memorial Health Care, Worcester, Massachusetts
Conditions: Degenerative Disc Disease, Spondylolisthesis
Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2
Recruiting
This project includes two projects. One is looking for new genes that cause Charcot Marie Tooth disease (CMT). The other is looking for genes that do not cause CMT, but may modify the symptoms a person has.
Gender:
All
Ages:
All
Trial Updated:
02/10/2023
Locations: Harvard/Massachusetts General Hospital, Boston, Massachusetts
Conditions: Charcot-Marie-Tooth Disease, Type Ia (Disorder), HMSN
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others
Recruiting
This is an observational longitudinal study to determine the natural history and genotype-phenotype correlations of disease causing mutations in Charcot Marie Tooth disease (CMT) type 1B (CMT1B), 2A (CMT2A), 4A (CMT4A), and 4C (CMT4C).
The investigators will also be determine the capability of the newly developed CMT Pediatric Scale (CMT Peds scale) and the Minimal Dataset to measure impairment and perform longitudinal measurements in patients with multiple forms of CMT over a five year window
Gender:
All
Ages:
All
Trial Updated:
02/10/2023
Locations: Harvard/Massachusetts General Hospital, Boston, Massachusetts
Conditions: Charcot Marie Tooth Disease
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in Subjects With Neovascular (Wet) Age-Related Macular Degeneration (AMD) or Subjects With Diabetic Macular Edema (DME)
Recruiting
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in subjects with Neovascular (wet) Age-Related Macular Degeneration (AMD) or subjects with Diabetic Macular Edema (DME)
Gender:
All
Ages:
18 years and above
Trial Updated:
02/09/2023
Locations: Ophthalmic Consultants of Boston, Boston, Massachusetts
Conditions: Neovascular Age-related Macular Degeneration, Diabetic Macular Edema