There are currently 243 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
Lipids and Energy Study: Optimizing the Analysis of Lipids and Energy Metabolism in Blood Samples
NCT04981288
Recruiting
The proposed research is a feasibility pilot trial designed to optimize the remote collection dried blood spots (DBS) from a finger stick and the analysis of fatty acid from the DBS and to optimize the analysis of mitochondria activity (or energy metabolism) from peripheral blood mononuclear cells (PBMC) or white blood cell samples. Participants in this study will provide a blood sample from venous blood draw and finger sticks. One finger stick collection will be completed remotely using a DBS k... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2025
Locations: The Ohio State University Human Nutrition Laboratory, Columbus, Ohio
Conditions: Healthy
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Eccentric Muscle Training, Stimulation, and Biomarkers in SCI
NCT05337982
Recruiting
The investigators are studying a new rehabilitation treatment for individuals trying to recover walking after spinal cord injury (SCI). The investigators will test conditions in the blood and spinal fluid to determine the best time to start this new training program. This will include checking for certain features called biomarkers by testing participants' spinal fluid and blood and compare these features to individuals without SCI. These features will help investigators determine when to start... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
10/24/2024
Locations: The Ohio State University, Columbus, Ohio +1 locations
Conditions: Spinal Cord Injuries, Healthy
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Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT)
NCT05628974
Recruiting
This is a single-center study at the Cleveland Clinic Main Campus designed to study biomarkers in healthy individuals to identify novel mechanisms of platelet activation and how platelets drive vascular inflammation and thrombosis in diseases.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/12/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Healthy
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High-Fidelity Patient Simulation on Clinical Reasoning Skills and Interprofessional Competencies
NCT06549998
Recruiting
The proposed study is looking to examine the effects of High-Fidelity Patient Simulation (HFPS) on clinical reasoning skills and interprofessional competencies in Physical Therapy and Nursing students. The proposed study will have two objectives: 1. Assess the use of HFPS and whether it has an effect of improving physical therapy and nursing student performance related to clinical reasoning skills during simulated clinical situations. 2. Assess the use of HFPS and whether it has an effect of i... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
09/16/2024
Locations: Youngstown State University, Youngstown, Ohio
Conditions: Healthy
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Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria
NCT05650112
Recruiting
This Phase 1, first-in-human, randomized, double-blinded, placebo controlled study is evaluating FB-001 in healthy volunteers (Part 1) and participants diagnosed with enteric hyperoxaluria (Part 2). Eligible participants receive investigational product and undergo safety monitoring, evaluations and subsequent follow-up after investigational product administration.
Gender:
All
Ages:
Between 18 years and 74 years
Trial Updated:
01/23/2023
Locations: Medpace Clinical Pharmacology Unit, Cincinnati, Ohio
Conditions: Healthy, Enteric Hyperoxaluria
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A Study to Learn How Different Amounts of the Study Medicine Called PF-08049820 Are Tolerated and Act in the Body in Healthy Adults
NCT06686797
Recruiting
The purpose of this study is to learn about the safety of the study medicine called PF-08049820 in healthy adults. The study will also see: * how the body processes the study medicine and * if food affects the amount of study medicine in the blood. The study medicine is developed for the treatment of moderate to severe atopic dermatitis, also known as eczema. People with this condition may have severe itching and rashes on the skin. The study is seeking participants who: 1. Are males or fema... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/19/2025
Locations: Pfizer Clinical Research Unit - New Haven, New Haven, Connecticut
Conditions: Healthy
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Effects of Sleep Disruption on Drug Response
NCT03680287
Recruiting
The central scientific premise of the proposed study is that sleep disruption (SD) will influence individuals' subjective response to blinded medication administration. The investigators further believe these responses will vary among patients who have chronic low back pain (CLBP) vs. healthy controls, and that sex will moderate effects. The proposed study evaluates whether CLBP patients' subjective responses to study medication administration are altered by SD. The investigators focus on two o... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
02/18/2025
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Low Back Pain, Recurrent, Healthy
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Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 1
NCT06601686
Recruiting
The goal of this clinical trial is to learn whether brain stimulation technology can help people reach a meditative state quickly and easily without years of meditation training. The researchers want to see if this will help people distance themselves from their thoughts and feeling, and if this will lead to improvements in openness and wellbeing the same way meditation can. Participants will: * Complete questionnaires * Perform a guided meditation task (The Bell Task) * Wear a high density el... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/18/2025
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Healthy
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Early Detection of Vascular Dysfunction Using Biomarkers From Lagrangian Carotid Strain Imaging
NCT04632485
Recruiting
The purpose of this research is assess imaging and identification of soft plaque that undergoes large deformations or strain will identify plaque vulnerable to rupture which could lead to 'silent strokes'. Validation of current study results with MRI will foster use of real-time ultrasound (US) strain imaging and strain indices as a screening tool for identifying normal human participants susceptible to increased vascular aging and developing plaque prone to rupture or micro-embolization. Curre... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/18/2025
Locations: Department of Medical Physics, University of Wisconsin, Madison, Wisconsin
Conditions: Healthy, Carotid Artery Diseases
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A Study to Test How Zongertinib is Taken up in the Blood of People With and Without Liver Problems
NCT06692322
Recruiting
This study is open to adults between 18 and 80 years of age. People with a body mass index (BMI) between 18 and 42 kg/m\^2 can take part. Women can only participate if they cannot get pregnant. This study includes people with mild liver problems, people with moderate liver problems, and people without liver problems as a matching control. The purpose of this study is to find out how mild and moderate liver problems affect how the body handles a medicine called zongertinib. Participants take zon... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/17/2025
Locations: American Research Corporation at the Texas Liver Institute, San Antonio, Texas
Conditions: Liver Diseases, Healthy
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The ENHANCE Study: taVNS and Psilocybin
NCT05866471
Recruiting
This study will examine whether combining a single dose of psilocybin with non-invasive transcutaneous auricular vagus nerve stimulation (taVNS), a potential inducer of neuroplasticity and enhanced memory formation, will enhance the long-term beneficial behavioral effects of psilocybin when compared to sham taVNS or no VNS by allowing memory for insights gained during the psychedelic experience to remain vivid after they will have faded in subjects who receive psilocybin followed by sham taVNS o... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
02/17/2025
Locations: University of Wisconsin - Madison, Madison, Wisconsin
Conditions: Healthy, Psychedelic Experiences, Vagus Nerve Stimulation
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A Study of V330 in Healthy Younger (18 to 49 Years Inclusive) and Healthy Older (60 to 79 Years Inclusive) Participants (V330-001)
NCT06630117
Recruiting
The goal of this study is to learn whether a new vaccine, V330, is safe and learn how well the body's immune system responds by making antibodies after receiving V330.
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
02/13/2025
Locations: California Clinical Trials Medical Group managed by PAREXEL (Site 0002), Glendale, California +3 locations
Conditions: Healthy
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