There are currently 226 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Autism participants are California, Florida, Texas and Maryland.
Eccentric Muscle Training, Stimulation, and Biomarkers in SCI
NCT05337982
Recruiting
The investigators are studying a new rehabilitation treatment for individuals trying to recover walking after spinal cord injury (SCI). The investigators will test conditions in the blood and spinal fluid to determine the best time to start this new training program. This will include checking for certain features called biomarkers by testing participants' spinal fluid and blood and compare these features to individuals without SCI. These features will help investigators determine when to start... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
12/19/2023
Locations: The Ohio State University, Columbus, Ohio +1 locations
Conditions: Spinal Cord Injuries, Healthy
Register for Updates
Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT)
NCT05628974
Recruiting
This is a single-center study at the Cleveland Clinic Main Campus designed to study biomarkers in healthy individuals to identify novel mechanisms of platelet activation and how platelets drive vascular inflammation and thrombosis in diseases.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/24/2023
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Healthy
Register for Updates
Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria
NCT05650112
Recruiting
This Phase 1, first-in-human, randomized, double-blinded, placebo controlled study is evaluating FB-001 in healthy volunteers (Part 1) and participants diagnosed with enteric hyperoxaluria (Part 2). Eligible participants receive investigational product and undergo safety monitoring, evaluations and subsequent follow-up after investigational product administration.
Gender:
All
Ages:
Between 18 years and 74 years
Trial Updated:
01/23/2023
Locations: Medpace Clinical Pharmacology Unit, Cincinnati, Ohio
Conditions: Healthy, Enteric Hyperoxaluria
Register for Updates
Imaging Techniques in MRI
NCT01130545
Recruiting
Background: - Magnetic resonance imaging (MRI) scans must be performed according to specified sets of parameters that provide optimal images of each organ and each area of the body. These scanning parameters are often specific to the institution or organization at which they are employed, and may also depend on the manufacturer of the MRI scanning equipment. Because MRI scanning equipment is always being updated and upgraded, researchers are interested in developing new and optimized scanning p... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
05/03/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Cardiac Risk Factors, Healthy, Healthy Volunteers
Register for Updates
Influence of Brain Oscillation-Dependent TMS on Motor Function
NCT03288220
Recruiting
Background: When people have a stroke, they often have difficulty moving their arms and hands. Transcranial magnetic stimulation (TMS) can improve how well people with and without stroke can move their arms and hands. But the effects of TMS are minor, and it doesn t work for everyone. Researchers want to study how to time brain stimulation so that the effects are more consistent. Objective: To understand how the brain responds to transcranial magnetic stimulation so that treatments for people... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy, Stroke, Normal Physiology, Aging
Register for Updates
Effectiveness of Aquamin® in Mitigating Halitosis
NCT05058638
Recruiting
The purpose of this study is to assess whether Aquamin®, a multi-mineral natural product from red marine algae, can help reduce halitosis when taken for 90 days.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
05/03/2024
Locations: University of Michigan School of Dentistry, Ann Arbor, Michigan
Conditions: Healthy, Halitosis
Register for Updates
Study of New Magnetic Resonance Imaging Methods of the Brain
NCT00004577
Recruiting
The purpose of this investigation is to develop improved magnetic resonance imaging (MRI) techniques and hardware for studying brain function. MRI is a diagnostic tool that provides information about brain chemistry and physiology. This study will evaluate new MRI methods for monitoring blood flow to regions of the brain in response to simple tasks. The MRI machine used in this study is more powerful than those in most hospitals, permitting a higher visual resolution. Normal healthy volunteers... Read More
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
05/02/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy, Magnetic Resonance Imaging, Adult, Brain Mapping, fMRI, Healthy Volunteer
Register for Updates
Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity
NCT04436731
Recruiting
Patients with sleep apnea are at increased risk of developing cardiovascular disease - with women at potentially greater risk than men. Contributing mechanisms are not well understood, but may be related to how women respond to low oxygen and, given over 70% of patients with sleep apnea are obese, the impact of obesity. This project seeks to increase our understanding of mechanisms that may contribute to sex differences in the cardiovascular response to low oxygen with the hope that this knowled... Read More
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
05/02/2024
Locations: University of Missouri-Columbia, Columbia, Missouri
Conditions: Obesity, Healthy, Vasoconstriction, Vasodilation
Register for Updates
A First-in-Human Safety Trial of MTX-463
NCT06401213
Recruiting
A randomized, double-blind, placebo-controlled, single ascending dose (SAD) and multiple ascending dose (MAD) study to assess the safety, tolerability, and PK of single and multiple ascending doses of MTX-463 administered in healthy adults.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/02/2024
Locations: ICON, Salt Lake City, Utah
Conditions: Healthy
Register for Updates
Imaging mGluR5 and Synaptic Density in Psychiatric Disorders
NCT03898297
Recruiting
This research study is designed to look at the involvement of the glutamate system and synaptic density in depression and bipolar disorder. Each participant will undergo a screening appointment to determine study eligibility. Thereafter, the study will take 2 or 3 visits depending on schedule availability and will consist of a combination of one magnetic resonance imaging (MRI) or functional magnetic resonance imaging (fMRI) scan, one proton magnetic resonance spectroscopy (MRS) and/or one C13 M... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/02/2024
Locations: Yale University PET Center, New Haven, Connecticut
Conditions: Major Depressive Disorder, Bipolar Disorder, Healthy
Register for Updates
1a/1b Study of OPT101 First in Human Study Assessing Safety and Tolerability of 15-mer Peptide.
NCT04589403
Recruiting
This is a first-in-human study, Phase 1, randomized, placebo-controlled, double blinded study that will be conducted in 2 parts.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
05/01/2024
Locations: IMMUNOe Research, Centennial, Colorado
Conditions: Healthy
Register for Updates
A Study to Test How Avenciguat (BI 685509) is Taken up in the Body of People With and Without Liver Problems
NCT06272058
Recruiting
This study is open to people with and without severe liver problems. People can join the study if they are 18 to 80 years of age and have a body mass index (BMI) between 18.5 and 42 kg/m2. Avenciguat (BI 685509) is a medicine that is being developed to treat high blood pressure in the portal vein (main vessel going to the liver). The purpose of this study is to find out whether having liver problems influences how Avenciguat (BI 685509) is taken up in the body. All participants take Avenciguat... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/30/2024
Locations: Orlando Clinical Research Center, Orlando, Florida +1 locations
Conditions: Healthy, Liver Diseases
Register for Updates