Colorado is currently home to 1810 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Terumo Aortic Global Endovascular Registry
NCT04246463
Recruiting
Multi-arm, multi-center, open label, prospective observational registry designed to obtain safety and performance data on the use of CE marked and custom Terumo Aortic endovascular grafts.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/19/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Abdominal Aortic Aneurysm, Thoracic Aortic Aneurysm, Surgery
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LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women
NCT05303636
Recruiting
The primary objective of this study is to evaluate the impact of LF111 and drospirenone (DRSP) 3.5 mg chewable tablets on bone mineral density (BMD) at the lumbar spine after 12 months (13 medication cycles) of investigation in comparison to non-hormonal contraceptive methods. Secondary objectives include further evaluating the impact of LF111 and DRSP 3.5 mg chewable tablets on BMD and bone turnover after 12 months (13 medication cycles) in comparison to non-hormonal contraceptive methods and a... Read More
Gender:
FEMALE
Ages:
Between 14 years and 45 years
Trial Updated:
06/15/2023
Locations: Velocity Clinical Research, Denver, Colorado
Conditions: Change in Bone Mineral Density, Bone Loss
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A New Securement Method for External Tunneled Central Venous Access Devices (CVAD)
NCT04462861
Recruiting
An external tunneled central venous access device (CVAD) is a small plastic tube that is tunneled under the skin into a major vein for long-term use (Figure 1). Patients who require a tunneled CVAD are some of the sickest patients we encounter and include oncology, hematology, and gastrointestinal (intestinal failure) patients. These patients are heavily reliant on their tunneled CVAD, which can be a lifeline for long-term administration of chemotherapeutics, IV medications, blood product transf... Read More
Gender:
ALL
Ages:
Between 31 days and 18 years
Trial Updated:
06/13/2023
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Central Venous Catheter Exit Site Infection, Central Venous Catheter Related Bloodstream Infection
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A Study of Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors
NCT05268666
Recruiting
The purpose of this study is to determine the maximum-tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of JBI-802 in patients with Advanced Solid Tumors.The efficacy of the RP2D will be evaluated in phase 2 in patients with solid tumors of neuroendocrine differentiation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/12/2023
Locations: Sarah Cannon Research Institute at HealthOne, Denver, Colorado
Conditions: Locally Advanced Solid Tumor, Metastatic Solid Tumor
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GCC19CART for Patients With Metastatic Colorectal Cancer
NCT05319314
Recruiting
Study ICT-GCC19CART-US-001 (CARAPIA-1) is a Phase 1 study evaluating the safety, tolerability, clinical activity, pharmacokinetics and pharmacodynamics of GCC19CART in subjects with relapsed or refractory metastatic colorectal cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/02/2023
Locations: University of Colorado Hospital - Anschutz Cancer Pavilion, Aurora, Colorado
Conditions: Colorectal Cancer
Register for Updates
Activity Restrictions After Inguinal Hernia Repair
NCT05867134
Recruiting
This research is intended to be a pilot study to identify differences in outcomes for varied lifting and physical activity precautions following surgical repair of single-sided inguinal hernias. The researchers hypothesize that when given the autonomy to return to activity at the patient's discretion, convalescence will decrease in comparison to a control group given specific precautions to refrain from lifting and strenuous activity. Specific aims include differences in convalescence and surgic... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
05/16/2023
Locations: Rocky Mountain Regional VA Medical Center, Aurora, Colorado
Conditions: Inguinal Hernia
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In-person vs. Virtual Delivery of a Group-based Prevention of Postpartum Depression
NCT05766475
Recruiting
The goal of this clinical trial is to test whether an established preventive intervention (group interpersonal therapy) delivered virtually shows the same benefits for preventing postpartum depression as it does when delivered in person.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/15/2023
Locations: Denver Health Medical Center, Denver, Colorado
Conditions: Postpartum Depression
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Nitrite-boosting Therapy for Improving Physiological Function in Patients With Chronic Kidney Disease
NCT03826147
Recruiting
Nitric oxide (NO) is an essential molecule in the body that is decreased in patients with chronic kidney disease (CKD), leading to reductions in vascular, movement ("motor") and cognitive functions. This study will determine if daily oral supplementation (3 months) with a supplement that increases NO in the body, i.e., nitrate-rich beetroot juice, improves vascular, motor and cognitive function in patients with CKD; this study will also provide insight into the biological reasons (mechanisms) by... Read More
Gender:
ALL
Ages:
Between 30 years and 80 years
Trial Updated:
05/15/2023
Locations: Integrative Physiology of Aging Laboratory, Boulder, Colorado
Conditions: Chronic Kidney Disease
Register for Updates
Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity
NCT05566483
Recruiting
The primary objectives of this study are to establish exercise training as a novel intervention to treat Long COVID and characterize the cardiorespiratory and autonomic physiology in these patients to precisely characterize mechanisms contributing to this syndrome.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/09/2023
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Post-acute Sequelae of SARS-CoV-2 Infection
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Healthy Starts: Repeated Exposure Pilot
NCT05639361
Recruiting
Decades of research have established that providing repeated exposure to new foods is the most robust strategy for promoting children's acceptance of new foods (1). However, there is little guidance on how best to translate this recommendation into everyday family life about how often to introduce children to new foods. We propose to conduct a proof-of-concept randomized trial that will evaluate three different schedules of repeated exposure to a novel vegetable, which will help to identify the... Read More
Gender:
ALL
Ages:
Between 9 months and 12 months
Trial Updated:
05/08/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Feeding Behavior
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Evaluating Adrenal Insufficiency in Adults With Eosinophilic Esophagitis on Chronic Swallowed Topical Steroids
NCT05246085
Recruiting
Eosinophilic esophagitis (EoE), a chronic inflammatory disease of the esophagus, is a clinical and financial burden to patients if left untreated. Often the natural history of the disease includes development of fibrosis and stricturing of the esophagus, acute food impactions, unplanned emergency room visits, and invasive procedures such as endoscopy. Currently there are no Food and Drug Administration (FDA) approved medications for the treatment of EoE. As such, pharmacologic options approved f... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
05/08/2023
Locations: University of Colorado Anschutz, Aurora, Colorado
Conditions: Eosinophilic Esophagitis
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Preventing Impaired Driving Among Adolescents
NCT04959461
Recruiting
The primary goal of this project is to evaluate the efficacy of webCHAT, a single-session web-intervention, on reducing impaired driving among adolescents receiving behind-the-wheel training at driver education programs.
Gender:
ALL
Ages:
Between 15 years and 17 years
Trial Updated:
05/04/2023
Locations: DriveSafe Driving School, Denver, Colorado
Conditions: Substance-Related Disorders
Register for Updates