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Depression Clinical Trials
A listing of 256 Depression clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
133 - 144 of 256
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There are currently 256 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Pennsylvania.
Featured Trial
Studying an Investigational Drug as Additional Therapy Treatment for Depression
Recruiting
This phase 2/3 study aims to assess the safety and effectiveness of an investigational drug (SEP-363856) as an additional treatment for adults with Major Depressive Disorder and who have not had success with antidepressants in treating their depression symptoms. This study may be suitable for you if you have been diagnosed with depression and your previous antidepressant treatments have not been effective. Should you express interest, the research site will contact you directly to provide further details and address any questions you may have about study requirements, risks/benefits, and compensation.
Conditions:
Depression
Depressive disorder
All Conditions
Featured Trial
Narcolepsy Clinical Study
Recruiting
The Vibrance Studies are researching the safety and effectiveness of a once-daily oral investigational study drug and how it may work in adults 18–70 years of age for the potential treatment of excessive daytime sleepiness (EDS) symptoms in adults with narcolepsy type 1 (NT1) or narcolepsy type 2 (NT2).
All participants who qualify will receive the study drug or placebo (a tablet that looks like the study drug but contains no active medicine), as well as study-related procedures and study-related laboratory tests at no cost. Compensation for time and travel may also be available.
All participants who qualify will receive the study drug or placebo (a tablet that looks like the study drug but contains no active medicine), as well as study-related procedures and study-related laboratory tests at no cost. Compensation for time and travel may also be available.
Conditions:
Narcolepsy
Narcolepsy With Cataplexy
Narcolepsy Without Cataplexy
Narcolepsy 1
Narcolepsy Type 1
Featured Trial
Type 2 Diabetes Clinical Trial
Recruiting
Can changing your breakfast improve your type 2 diabetes? If you have an HbA1C of 7.0% or higher, you are invited to participate in an online study at the University of Michigan.
Conditions:
Type 2 Diabetes
Diabetes Mellitus Type 2 in Obese
Diabetes Type Two
Type 2 Diabetes Mellitus
Diabete Type 2
Featured Trial
High Triglyceride Clinical Research Study
Recruiting
Living with high triglycerides? See if our clinical study is right for you.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Conditions:
High Triglycerides
High Triglyceride Level
Hypertriglyceridemia
Elevated Triglycerides
Triglycerides High
Combined Neuromodulation and Cognitive Training for Post-mTBI Depression
Recruiting
The primary goal of this clinical trial is to evaluate whether Personalized Augmented Cognitive Training (PACT) plus intermittent theta burst stimulation (iTBS) is effective for treating depression in Service Members, Veterans, and civilians who have sustained a mild TBI. Participants will receive PACT plus 20 sessions of iTBS or sham iTBS over 4 weeks. Assessments will occur at baseline, 2 weeks, 4 weeks, and 8 weeks. Researchers will compare the PACT+iTBS group to the PACT+sham iTBS group to s... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/01/2024
Locations: UCSD, La Jolla, California
Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression
Recruiting
This mechanistic study uses an anti anxiety drug and brain imaging to study the threat processing system and associated brain circuits in people with depression, anxiety disorders and comorbid depression and anxiety disorders. In a double blind, placebo controlled crossover design, up to 65 individuals will be recruited who will have a diagnosis of major depressive disorder (MDD) and at least one anxiety disorder (AD) (AD-MDD group), up to 65 participants will have a diagnosis of MDD and no diag... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/30/2024
Locations: Laureate Institute for Brain Research, Tulsa, Oklahoma
Conditions: Depression, Anxiety, Fear, Depression, Anxiety and Fear, Anxiety Disorders, Anxious Depression
Early Life Stress and Depression: Molecular and Functional Imaging
Recruiting
Severe childhood adversity accounts for a large portion of psychiatric illness, and an increased risk for major depressive disorder (MDD). For some individuals, childhood adversity has negative psychological and medical consequences; others preserve mental and physical health despite such experiences (they are resilient). In spite of this, little is known about the neurobiological mechanisms related to childhood adversity, especially oxidative stress abnormalities in the brain. To fill this gap,... Read More
Gender:
FEMALE
Ages:
Between 20 years and 32 years
Trial Updated:
10/28/2024
Locations: McLean Hospital, Belmont, Massachusetts
Conditions: Depression, Trauma, Psychological
IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment)
Recruiting
The purpose of this research study is to evaluate a mobile application (app) for depression treatment called "Moodivate" among cancer survivors. Moodivate was developed by our research team to assist with the treatment of depressed mood.
Participants will be randomly assigned to either download the mobile app, "Moodivate", or not. Approximately 2/3 of participants enrolled will receive the mobile app and the remaining 1/3 will not.
All participants will complete electronic questionnaire measur... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/28/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care
Recruiting
The purpose of this study is to demonstrate whether Behavioral Activation for depression delivered via home based telehealth (BA-HT) is effective in improving social and role functioning in Veterans recently discharged from Cardiovascular disease (CVD-related) inpatient care. Eligible participants will receive either (1) twelve sessions of BA-HT or (2) standard best practices post CVD hospitalization care.
Study participants will be 132 Veterans discharged from the Ralph H. Johnson VA Medical C... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
10/25/2024
Locations: Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina
Conditions: Depression, Cardiovascular Diseases
Cognitive Behavioral and Faith Fellowship to Improve Thy Health
Recruiting
Investigators will examine the efficacy of a faith-based depression intervention, in reducing symptoms of depression among African American adults in Wisconsin. Twelve church groups, each with 10 people (N=120) will be invited to participate. This intervention will be the first evidence-based, faith-based intervention designed for African Americans if validated.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/24/2024
Locations: Second Baptist Church, Madison, Wisconsin +1 locations
Conditions: Depression
Testing a Scalable Model of Care to Improve Patients Access to Mental Health Services After Traumatic Injury
Recruiting
The purpose of this study to learn about patients' experience with the Trauma Resilience and Recovery program (TRRP) and/or the enhanced care group.
Gender:
ALL
Ages:
16 years and above
Trial Updated:
10/24/2024
Locations: George Washington University Hospital, Washington, Virginia
Conditions: Posttraumatic Stress Disorder, Depression
Psilocybin in Chronic Low Back Pain and Depression
Recruiting
This study seeks to provide insight on psilocybin's effects on mechanisms of chronic pain among patients with co-morbid chronic low back pain and depression (CLBP+D).
Participants will receive either a single high-dose of psilocybin (25mg absolute dose) or methylphenidate (40mg absolute dose). Participants will be asked to complete assessments of pain, depressive symptoms, and more general questionnaires regarding the participants experiences during the experimental sessions and the associated... Read More
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
10/24/2024
Locations: Johns Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Chronic Low-back Pain, Depression
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Recruiting
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Gender:
ALL
Ages:
Between 12 years and 20 years
Trial Updated:
10/23/2024
Locations: El Monte High School, El Monte, California +20 locations
Conditions: Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior, Sexual Minority Stress, Suicidality, Substance Use, Bullying, Harassment
Exploring Virtual Reality Adventure Training Exergaming
Recruiting
The current project aims to design and implement an 8-week Virtual Reality Adventure Therapy Exergaming (V-RATE) intervention focused on women veterans. A randomized controlled trial using a repeated measure design with a 1-month follow-up assessment will be employed to examine effects on physical and mental health outcomes.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
10/23/2024
Locations: University of Texas at Arlington, Arlington, Texas
Conditions: Physical Activity, Sedentary Behavior, Depression, Cognitive Function, Post Traumatic Stress Disorder, Quality of Life, Anxiety
The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic
Recruiting
The goal of this clinical trial is to test the effectiveness and implementation of delivering Enhanced Brief Interpersonal Psychotherapy (IPT-B), an evidence-based maternal depression treatment, to mothers of children aged 4-11 years in an urban pediatric asthma clinic. Researchers will compare Enhanced IPT-B and supplemented usual care (brief care coordination). The main questions the trial aims to answer are:
1. Does Enhanced IPT-B decrease maternal depressive symptoms?
2. Does Enhanced IPT-B... Read More
Gender:
ALL
Ages:
4 years and above
Trial Updated:
10/21/2024
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Asthma in Children, Depression
Evaluating Procedures for a Study of the AYA Survivors Coping and Emotional Needs Toolkit
Recruiting
The investigators developed a digital intervention that aims to help adolescent and young adult cancer survivors (AYAs) manage symptoms of depression. This tool includes daily mood tracking, a psychoeducational module about cancer and depression, four components that are based on evidence-based interventions for depression. The goal of this study is to evaluate the acceptability of procedures for a future trial in which the investigators will test which component or combination of components mea... Read More
Gender:
ALL
Ages:
Between 15 years and 39 years
Trial Updated:
10/16/2024
Locations: East Carolina University, Greenville, North Carolina
133 - 144 of 256