There are currently 281 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Pennsylvania.
Feasibility of a Prenatal Yoga Mobile App in African American Pregnant Women
NCT06353113
Recruiting
The goal of this research is to test if a prenatal yoga app can improve well-being in African American/Black (AA) pregnant women. The main questions it aims to answer are: Is the Down Dog prenatal yoga app feasible for AA pregnant women? How does mental and physical health change after using the Down Dog app for 12-weeks? What cultural adaptations to the Down Dog app are needed? The study lasts for 12 weeks and participants are asked to: do prenatal yoga with the app for at least 20 min/day,... Read More
Gender:
Female
Ages:
Between 18 years and 46 years
Trial Updated:
06/18/2024
Locations: San Diego State University, San Diego, California
Conditions: Pregnancy Related, Mental Health Issue, Discrimination, Racial, Stress, Depression
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A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
NCT04777357
Recruiting
Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States. The treatment of the depressive episodes of bipolar disorder in the pediatric population has not been as widely studied as the treatment of depressive episodes in bipolar disorder in adults, therefore pharmacotherapeutic options are limited. Given the change in disease state and safety demonstrated in adults with depressive episodes associate... Read More
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
06/18/2024
Locations: Pillar Clinical Research /ID# 226504, Bentonville, Arkansas +62 locations
Conditions: Depression, Bipolar I Disorder
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Mood Lifters for Undergraduates
NCT05684120
Recruiting
Large-scale, effective, low-cost, and evidence-based programs that can nimbly translate new research discoveries into prevention and care for psychosocial-based problems are urgently needed since the vast majority of people who need evidence-based care do not receive it. The purpose of this randomized control trial is to investigate the feasibility and efficacy of a Mood Lifters group template specifically for undergraduate students. Mood Lifters is an effective peer-led program that improves o... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Depression, Anxiety, Mood Disorders, Mental Health Wellness 1, Stress
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HypErthermia as an Additional Treatment for the Biology and Experience of Depression: Study 2
NCT05708976
Recruiting
This randomized two-arm intervention trial administers 8 weekly cognitive behavioral therapy (CBT) sessions and 4 bi-weekly active whole-body hyperthermia (active WBH) sessions or 4 bi-weekly sham WBH sessions to adults aged 18 years or older with major depressive disorder (MDD).
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: University of California San Francisco, San Francisco, California
Conditions: Major Depressive Disorder, Depression
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Antidepressant Effects of TS-161 in Treatment-Resistant Depression
NCT04821271
Recruiting
Background: Major depressive disorder (MDD) is a common, chronic mental illness. It can take weeks to months for antidepressants to work. Researchers want to test a new drug that might act more rapidly. Objective: To see if TS-161 will improve symptoms of depression in people with MDD. Eligibility: Adults ages 18-65 with MDD without psychotic features. Design: Participants will be screened under a separate protocol. They will have blood tests. They will complete surveys about their sympto... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/15/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Major Depressive Disorder, Treatment-Resistant Depression, Depression
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Diet and Depression
NCT06252701
Recruiting
This study is a pilot open label crossover trial to assess the feasibility and acceptability of reducing ultra- processed foods (UPF) in a personalized manner from the diets of patients with major depressive disorder who eat a large percentage of UPF.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/14/2024
Locations: University of California, San Francisco, San Francisco, California
Conditions: Depression, Major Depressive Disorder, Weight Gain, Obesity, Metabolic Syndrome
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The Ukrainian Student Problem Solving Project
NCT06064578
Recruiting
The purpose of this study is to test the effectiveness of a universal, digital, single-session intervention for youth mental health, functioning, and well-being. The investigators will be providing access to a brief online program (Project SOLVE) for students as part of the school curriculum. Ukrainian students living in Poland will be randomly assigned to receive Project SOLVE either immediately or after 3 months. The program is designed to help students manage stress and reach their academic a... Read More
Gender:
All
Ages:
Between 10 years and 18 years
Trial Updated:
06/14/2024
Locations: Harvard University, Cambridge, Massachusetts
Conditions: Trauma, Anxiety, Depression, Child Behavior
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Perioperative Mental Health in Orthopedic Surgery
NCT05697835
Recruiting
This Hybrid 1 Study will test the effectiveness of a bundled intervention comprised of behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing Orthopedic surgery (compared with usual care), while examining implementation outcomes.
Gender:
All
Ages:
60 years and above
Trial Updated:
06/14/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Orthopedic Surgery, Older Adults, Depression, Anxiety
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Intern Health Study 2024
NCT06465680
Recruiting
The aim of this trial is to evaluate the efficacy of an intervention (delivered through a smartphone) for improving the mood, physical activity, and sleep of medical interns.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/13/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Depression, Mood, Sleep, Physical Activity
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Safe Mothers, Safe Children Initiative
NCT04752618
Recruiting
The purpose of this study is to assess the efficacy of the combined interventions, Skills Training in Affective and Interpersonal Regulation (STAIR) and Parent-Child Interaction Therapy (PCIT) or P-STAIR, for treating maternal PTSD and reducing maltreatment recidivism.
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/13/2024
Locations: McSilver Institute for Poverty Policy and Research, New York, New York
Conditions: PTSD, Depression, Child Maltreatment
Register for Updates
Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
NCT06261463
Recruiting
The proposed study draws on prior research to evaluate the feasibility, acceptability and explore preliminary effectiveness of Coffee and Family Education and Support, Version (CAFES2) using a pilot randomized type 1 hybrid effectiveness-implementation design. CAFES2 is a peer-led family and social strengthening multiple family group intervention that is designed to respond to multi-level needs of refugee families. Results of the trial will contribute to the emerging evidence base on family-base... Read More
Gender:
All
Ages:
Between 12 years and 45 years
Trial Updated:
06/12/2024
Locations: University of Illinios Chicago, Chicago, Illinois
Conditions: Depression, Anxiety, PTSD, Family Dynamics, Social Functioning, Family Support, Family Relations
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Engaging sgACC With TMS for Depression
NCT06266390
Recruiting
The purpose of this study is to investigate the responses of the brain region known as the subgenual anterior cingulate cortex (sgACC) during transcranial magnetic stimulation (TMS) in individuals with depression. Specifically, investigators aim to determine whether the sgACC is engaged when TMS is delivered to specific targets and if the engagement of sgACC changes throughout a full TMS treatment intervention. To achieve this goal, the investigators will employ a combination of TMS and Magnetic... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/12/2024
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Depression, Major Depressive Disorder, Persistent Depressive Disorder
Register for Updates