There are currently 254 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Pennsylvania.
Cannabis for Palliative Care in Cancer
NCT06266611
Recruiting
Many cancer patients suffer from pain, sleep, and mood problems and are using cannabis to relieve these symptoms. Cannabis may provide such relief but may also produce negative side effects including cognitive impairment, an especially problematic issue for cancer patients, indicating more research on cannabis use in the cancer context is required. In this endeavor, the present study seeks to compare the use of hemp-derived CBD (Cannabidiol) with and without THC (Delta-9-tetrahydrocannabinol) ve... Read More
Gender:
ALL
Ages:
25 years and above
Trial Updated:
12/03/2024
Locations: Anschutz Health Sciences Building, Aurora, Colorado
Conditions: Sleep, Anxiety, Depression, Pain
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Mood Lifters for Undergraduates
NCT05684120
Recruiting
Large-scale, effective, low-cost, and evidence-based programs that can nimbly translate new research discoveries into prevention and care for psychosocial-based problems are urgently needed since the vast majority of people who need evidence-based care do not receive it. The purpose of this randomized control trial is to investigate the feasibility and efficacy of a Mood Lifters group template specifically for undergraduate students. Mood Lifters is an effective peer-led program that improves o... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Depression, Anxiety, Mood Disorders, Mental Health Wellness 1, Stress
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Prevention of Anhedonia in Children
NCT05988138
Recruiting
This trial will test the effects of a positive emotion-focused preventive intervention on reward responsiveness in children of mothers with histories of depression and anhedonia.
Gender:
ALL
Ages:
Between 8 years and 12 years
Trial Updated:
12/02/2024
Locations: Jesup/Hobbs Building, Nashville, Tennessee
Conditions: Anhedonia, Depression
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WellPATH-PREVENT: A Mobile Intervention for Middle-Aged and Older Adults Hospitalized for Suicidal Ideation or Attempt
NCT05183230
Recruiting
The goal of this project is to test whether WellPATH-PREVENT (a novel, mobile psychosocial intervention) improves a specific aspect of emotion regulation, i.e., cognitive reappraisal ability, and reduces suicide risk in middle-aged and older adults (50-90 years old) who have been discharged after a suicide-related hospitalization (i.e. for suicidal ideation or suicide attempt).
Gender:
ALL
Ages:
Between 50 years and 90 years
Trial Updated:
11/22/2024
Locations: New York Presbyterian Hospital/Weill Cornell Medicine, New York, New York +1 locations
Conditions: Suicide, Attempted, Suicidal Ideation, Depression
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Safe Mothers, Safe Children Initiative
NCT04752618
Recruiting
The purpose of this study is to assess the efficacy of the combined interventions, Skills Training in Affective and Interpersonal Regulation (STAIR) and Parent-Child Interaction Therapy (PCIT) or P-STAIR, for treating maternal PTSD and reducing maltreatment recidivism.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: McSilver Institute for Poverty Policy and Research, New York, New York
Conditions: PTSD, Depression, Child Maltreatment
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Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors
NCT06538246
Recruiting
Conditions treated in intensive care units (ICUs) such as the acute respiratory distress syndrome (ARDS), congestive heart failure, COVID pneumonia, and sepsis are common. These can lead to high rates of depression, anxiety, and PTSD that worsen quality of life. Yet there are few effective strategies able to overcome barriers of limited access to mental health care. Even less is known about the experiences of patients from racially and ethnically minoritized populations because of they haven't b... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2024
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Depression, Anxiety, Post-traumatic Stress Disorder, Stress, Worries; Pain or Disability, Breath Shortness
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Brief Interventions for Coping with Distress
NCT05779761
Recruiting
This study is being done to compare the effectiveness of three different skills trainings to cope with distress. These three trainings are: 1) an attention skills training, 2) an attention and reflective thought skills training, and 3) a health and wellness education training.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/18/2024
Locations: Teachers College, Columbia University, New York, New York
Conditions: Distress, Emotional, Emotional Dysfunction, Anxiety, Depression
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Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches
NCT05176392
Recruiting
This study will assess the combined effectiveness of repetitive transcranial magnetic stimulation (rTMS) and telehealth based therapy in helping manage mild traumatic brain injury (mTBI) related headaches. The investigators hypothesize that active rTMS combined with telehealth therapy will provide marked reduction in mTBI related headaches and symptoms in comparison to their placebo counterparts.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/18/2024
Locations: VA San Diego Healthcare System, San Diego, California
Conditions: TBI (Traumatic Brain Injury), Headache, Depression
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Brain Stimulation and Decision-making
NCT04099056
Recruiting
Decision-making is an important process that is frequently shown to be impaired in patients with depression. While a number of preclinical and clinical studies have identified key regions involved in this process, it remains unclear exactly how these regions are influencing choice behavior especially when choices become more challenging. The goal of this project is to understand how these regions, such as the cingulate cortex, impact difficult choice behavior. Specifically, the researchers are i... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
11/14/2024
Locations: Emory University, Atlanta, Georgia
Conditions: Depression
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Study on Allopregnanolone and Depression in Women Across the Menopause Transition
NCT06238700
Recruiting
This study aims to identify how enhanced allopregnanolone activity (via pregnenolone) affects behavior and neurobiology that may underlie perimenopausal depression.
Gender:
FEMALE
Ages:
Between 40 years and 60 years
Trial Updated:
11/13/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Depression
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Compassion Meditation vs. Health Education for Veterans
NCT04651296
Recruiting
Chronic pain (CP) is a major health problem for military Veterans, and CP is often associated with comorbid mental health problems, including posttraumatic stress disorder (PTSD) and depression. CP with psychological comorbidity is associated with increased healthcare costs, medication use, risk of suicide and rates of disability and reduced quality of life. Current empirically supported treatments do not always lead to substantial improvements (up to 50% of patients drop out or are do not respo... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: VA San Diego Healthcare System, San Diego, CA, San Diego, California
Conditions: Chronic Pain, Stress Disorders, Posttraumatic, Depression
Register for Updates
Families With Pride ("Familias Con Orgullo").
NCT06057337
Recruiting
This study will evaluate the effects of a parenting intervention for Hispanic sexual minority youth in preventing/reducing drug use and depressive symptoms. It will also examine whether the intervention improves parent social support for the adolescent, parent acceptance, family functioning, and whether it reduces general stress and stress associated with being a Hispanic sexual minority.
Gender:
ALL
Ages:
Between 13 years and 19 years
Trial Updated:
11/12/2024
Locations: University of Miami, Coral Gables, Florida
Conditions: Depression, Drug Use
Register for Updates