There are currently 252 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Pennsylvania.
Cannabidiol and Older Adult Cannabis Users
NCT06290063
Recruiting
Cannabis use increased 10 fold among adults over the age of 65 between 2014 and 2016 but very little data exists on the extent of their harmful effects on health and behavior. The overarching goal of this project is to test a novel harm reduction strategy in which older individuals who seek to use cannabis for pain, anxiety or mood problems (depression/anxiety) will be randomly assigned to one of three conditions in an 8 week randomized controlled trial: hemp-derived CBD+THC, hemp-derived CBD-TH... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/06/2024
Locations: University of Colorado at Boulder, Boulder, Colorado
Conditions: Sleep, Anxiety, Depression, Pain
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Enhancing Purpose and Well-Being Through a Volunteering Experience Connecting Veterans With English Language Learners
NCT06324383
Recruiting
The goal of this study is to refine and test a strategy for engaging Veterans with symptoms of depression, anxiety, and/or PTSD (Post Traumatic Stress Disorder) as volunteers to help English language learners (ELLs) improve their speaking skills via structured conversations using videoconferencing.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: Center for Clinical Management Research (CCMR), North Campus Research Complex, Ann Arbor, Michigan
Conditions: Depression, Anxiety, Post Traumatic Stress Disorder
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Reaching Out to Distressed Medical Residents, Fellows and Faculty
NCT02010866
Recruiting
The purpose of this study is to study whether distressed medical residents, fellows, and faculty health professionals benefit from completing online an anonymous and interactive screening of stress, depression, substance use, and suicidal thoughts. The screening and ability to interact online with a clinician anonymously are hypothesized to increase willingness to come for counseling in person. Suicide risk factors are expected to be lower once the distressed medical trainee or faculty member re... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/27/2024
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Depression, Suicide
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Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
NCT06374277
Recruiting
Socioeconomically disadvantaged populations with multiple chronic conditions have high rates of nonadherence to essential chronic disease medications after hospital discharge. Medication nonadherence after hospital discharge is significantly associated with increased mortality and higher rates of readmissions and costs among these patients. Major patient-reported barriers to essential medication use after hospital discharge among low-income individuals are related to social determinants of healt... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: University of Tennessee Medical Center, Knoxville, Tennessee +1 locations
Conditions: Diabetes, Hypertension, High Cholesterol/Hyperlipidemia, Coronary Artery Disease, Congestive Heart Failure, Chronic Lung Disease, Chronic Kidney Diseases, Arrythmia, Stroke, Depression, Anxiety, Pulmonary Embolism, Heart Attack
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An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression
NCT05466851
Recruiting
This research study is studying how thoughts, feelings, surroundings, and individual biology may contribute to why and how people experience anxiety or depression. We are trying to find out the wide variety of reasons that people may experience anxiety or depression, and why different people are helped by different forms of treatment. We are trying to determine why people stay in treatment, and what factors contribute to a positive or negative response to treatment. These reasons may be due to... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/15/2024
Locations: Singula Institute, 353 Lexington Avenue (Room 600), New York, New York
Conditions: Depression, Anxiety Disorders, Stress Related Disorder
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Buspirone and Melatonin for Depression Following Traumatic Brain Injury
NCT04400266
Recruiting
Traumatic brain injuries (TBIs) are common. Post-TBI depression is associated with anxiety, aggression, fatigue, distractibility, anger, irritability, and rumination. The current research group conducted a pilot clinical trial, which investigated the novel treatment combination of buspirone and melatonin (B+MEL) in outpatients with clinical depression. Compared to placebo, B+MEL was associated with a significant improvement in depressive symptoms. Depression following TBI may be different from c... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
04/09/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations
Conditions: Depression, Brain Injuries, Traumatic
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M-O-M-S on the Bayou: Implementation of an Intervention for Mental Health in Pregnancy
NCT05838404
Recruiting
Disasters have negative effects in the short term (physical trauma, adverse environmental exposures, and unstable housing) and the long term (relocation, changes in family functioning, and negative economic effects), which interact with social determinants to worsen health among the most vulnerable women, infants, and communities. Trauma and severe stress are directly linked to pregnancy complications, and raise blood pressure during pregnancy, alter stress hormones, and increase vulnerability t... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/09/2024
Locations: Tulane University, New Orleans, Louisiana
Conditions: Anxiety, Depression
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Cardiac Markers in Depressed Patients With Coronary Heart Disease - R01HL147862
NCT04682769
Recruiting
Depression doubles the risk of death in patients with coronary heart disease (CHD), but so far, there is insufficient evidence that we can reduce the risk of death by treating depression. This study will investigate the cardiac risk markers that are associated with depression symptoms that remain despite treatment, and identify potential targets for their treatment. The results of the study will inform the development of more effective interventions to improve both depression and survival in pat... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/20/2024
Locations: Washington University, Saint Louis, Missouri
Conditions: Coronary Heart Disease, Depression
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Mechanisms of Behavioral Activation (BA)
NCT05548244
Recruiting
The investigators will be comparing brain (neural) activation of depressed adolescent patients before, during and after a course of Behavioral Activation (BA) therapy using functional magnetic resonance imaging (fMRI). In particular, the project seeks to determine whether BA targets different neural mechanisms for behavioral avoidance associated with low motivation as compared to threat avoidance. A group of healthy controls will also be scanned as a comparator group for behavioral and imaging m... Read More
Gender:
ALL
Ages:
Between 15 years and 17 years
Trial Updated:
02/29/2024
Locations: Emory University, Atlanta, Georgia +2 locations
Conditions: Depression
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A Closed Loop, Doctor to Patient, Mobile Application for Depression in People With Multiple Sclerosis
NCT05865405
Recruiting
The researchers want to find out if an electronic application called MS CATCH can enhance patients' and doctors' experiences during and in between clinical visits. MS CATCH is a smartphone-based tool which allows patients to enter their mood related symptoms at regular intervals, which is then available to their Neurologist in their electronic medical record. The neurologist is also able to view additional information from their medical record, and receives alerts for changes reported by the pat... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/16/2024
Locations: Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California
Conditions: Multiple Sclerosis, MS, Depression
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The Rapid Diagnosis of MCI and Depression in Patients Ages 60 and Over
NCT06011681
Recruiting
Mild cognitive impairment (MCI) leading to Alzheimer's disease and related disorders (ADRD) represents a significant health and economic burden of the rapidly expanding senior population. The accurate detection and diagnosis of MCI and its common comorbidity, late-life depression (LLD), is essential for prolonging patient quality of life and developing advancements in research and treatment options. The purpose of the proposed program is to refine Miro Health's A.I. to accurately detect, differe... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
01/18/2024
Locations: Miro Health, Sacramento, California +1 locations
Conditions: Depression, Mild Cognitive Impairment
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Implementation of the Parents Taking Action in Paraguay
NCT05780138
Recruiting
The principal aim of this study is to conduct a single group design pilot of a psychoeducational caregiver training (i.e., culturally adapted Parents Taking Action) with a group of family caregivers of young children with autism in Paraguay. The following research questions will be addressed: Research Question #1: What is the feasibility and acceptability of the intervention? Research Question #2: Do participants improve between pre and post-test on outcome measures? Parents will receive 10 wee... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/04/2024
Locations: University of Texas at Austin, Austin, Texas
Conditions: Depression, Autism
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