A Pilot Study to Examine the Impact of a Therapy Dog Intervention on Loneliness and Related Health Outcomes in Vulnerable Populations
Recruiting
The purpose of this research study is to test whether an animal-assisted interaction (AAI) intervention is better than conversation with another person or treatment as usual for improving mood, anxiety, loneliness, quality of life, and indicators of health care services such as number of hospitalizations, length of hospital stay, and cost of services. Participants will be patients admitted for an inpatient stay at Virginia Commonwealth University Health who meet the study entry requirements.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/17/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Loneliness, Depression, Anxiety, Quality of Life
Mindful Moms Randomized Control Trial
Recruiting
The purpose of this study is to test whether a program called "Mindful Moms" can be helpful for specific measures of mood and health in pregnant women with depressive symptoms, compared to group-based education workshops.
Gender:
Female
Ages:
18 years and above
Trial Updated:
10/10/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Depression
The Group Risk Reduction Intervention Therapy (GRRIT) Project
Recruiting
Investigators will evaluate a group format adaptation of Brief Cognitive-Behavioral Therapy for Suicide (i.e., G-BCBT) on suicide ideation (Aim 1), ability to use coping strategies (Aim 2), and overall mental health (exploratory analysis). The combination of tailored means safety counseling and training in evidence-based emotion regulation and cognitive flexibility skills delivered via a 12-session group therapy treatment will decrease service members' overall suicide risk. The group format will... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
09/26/2023
Locations: Naval Medical Center Portsmouth, Portsmouth, Virginia
Conditions: Suicidal Ideation, Suicide, Attempted, Coping Skills, Depression, Anxiety, PTSD
Testing a Scalable Model of Care to Improve Patients Access to Mental Health Services After Traumatic Injury
Recruiting
The purpose of this study to learn about patients' experience with the Trauma Resilience and Recovery program (TRRP) and/or the enhanced care group.
Gender:
All
Ages:
16 years and above
Trial Updated:
01/05/2023
Locations: George Washington University Hospital, Washington, Virginia
Conditions: Posttraumatic Stress Disorder, Depression
Yoga for Mental Health in Parkinson's Patients
Recruiting
This study is a waitlisted randomized controlled trial. We aim to assess the level of compliance for those learning the intervention and to evaluate the impact of the practice on neuropsychological and somatic outcomes using validated scales. Enrollment into the study will be ongoing until we are able to get a sufficient sample size as described in the "Statistical Consideration" section. Upon enrollment and randomization, surveys will be administered to both the intervention and control groups... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/29/2023
Locations: Beth Israel Deaconess Medical Centre, Boston, Massachusetts
Conditions: Stress, Anxiety, Depression, Parkinson Disease
Compassion Meditation vs. Health Education for Veterans
Recruiting
Chronic pain (CP) is a major health problem for military Veterans, and CP is often associated with comorbid mental health problems, including posttraumatic stress disorder (PTSD) and depression. CP with psychological comorbidity is associated with increased healthcare costs, medication use, risk of suicide and rates of disability and reduced quality of life. Current empirically supported treatments do not always lead to substantial improvements (up to 50% of patients drop out or are do not respo... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: VA San Diego Healthcare System, San Diego, CA, San Diego, California
Conditions: Chronic Pain, Stress Disorders, Posttraumatic, Depression
Poststroke Depression in Hemorrhagic Stroke
Recruiting
A double-blinded placebo-controlled randomized trial to evaluate the effect of preventative treatment of depression in survivors of aneurysmal subarachnoid hemorrhage (aSAH), a type of stroke.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
11/27/2023
Locations: Harborview Medical Center, Seattle, Washington
Conditions: Stroke Hemorrhagic, Depression
Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care
Recruiting
The purpose of this study is to demonstrate whether Behavioral Activation for depression delivered via home based telehealth (BA-HT) is effective in improving social and role functioning in Veterans recently discharged from Cardiovascular disease (CVD-related) inpatient care. Eligible participants will receive either (1) twelve sessions of BA-HT or (2) standard best practices post CVD hospitalization care. Study participants will be 132 Veterans discharged from the Ralph H. Johnson VA Medical C... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
11/24/2023
Locations: Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina
Conditions: Depression, Cardiovascular Diseases
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
Recruiting
Background: Most medications that treat depression take weeks or months to work. Researchers want to develop fast-acting treatments. One dose of ketamine has a rapid antidepressant effect. For most people, this lasts a week or less. Repeated doses of ketamine may help maintain this effect. Objective: Main Study: To study the effects of ketamine in treating depression. Ketamine Metabolites Substudy: To study how ketamine effects brain chemistry. To study how ketamine effects the brain. This... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/23/2023
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy Volunteer, Major Depressive Disorder, Depression
Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
Recruiting
The investigators will conduct a 12,500-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries
Gender:
All
Ages:
18 years and above
Trial Updated:
11/22/2023
Locations: Yale School of Medicine, New Haven, Connecticut +5 locations
Conditions: Surgery-Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity, Depression, Sleep Disorders, Circadian Rhythm
Brief Interventions for Coping With Distress
Recruiting
This study is being done to compare the effectiveness of three different skills trainings to cope with distress. These three trainings are: 1) an attention skills training, 2) an attention and reflective thought skills training, and 3) a health and wellness education training.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/21/2023
Locations: Teachers College, Columbia University, New York, New York
Conditions: Distress, Emotional, Emotional Dysfunction, Anxiety, Depression
A Closed Loop, Doctor to Patient, Mobile Application for Depression in People With Multiple Sclerosis
Recruiting
The researchers want to find out if an electronic application called MS CATCH can enhance patients' and doctors' experiences during and in between clinical visits. MS CATCH is a smartphone-based tool which allows patients to enter their mood related symptoms at regular intervals, which is then available to their Neurologist in their electronic medical record. The neurologist is also able to view additional information from their medical record, and receives alerts for changes reported by the pat... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
11/21/2023
Locations: Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California
Conditions: Multiple Sclerosis, MS, Depression