There are currently 281 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Pennsylvania.
Testing a Scalable Model of Care to Improve Patients Access to Mental Health Services After Traumatic Injury
NCT05497115
Recruiting
The purpose of this study to learn about patients' experience with the Trauma Resilience and Recovery program (TRRP) and/or the enhanced care group.
Gender:
All
Ages:
16 years and above
Trial Updated:
05/30/2024
Locations: George Washington University Hospital, Washington, Virginia
Conditions: Posttraumatic Stress Disorder, Depression
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The Group Risk Reduction Intervention Therapy (GRRIT) Project
NCT05401838
Recruiting
Investigators will evaluate a group format adaptation of Brief Cognitive-Behavioral Therapy for Suicide (i.e., G-BCBT) on suicide ideation (Aim 1), ability to use coping strategies (Aim 2), and overall mental health (exploratory analysis). The combination of tailored means safety counseling and training in evidence-based emotion regulation and cognitive flexibility skills delivered via a 12-session group therapy treatment will decrease service members' overall suicide risk. The group format will... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
11/28/2023
Locations: Naval Medical Center Portsmouth, Portsmouth, Virginia
Conditions: Suicidal Ideation, Suicide, Attempted, Coping Skills, Depression, Anxiety, PTSD
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Mindful Moms Randomized Control Trial
NCT04886856
Recruiting
The purpose of this study is to test whether a program called "Mindful Moms" can be helpful for specific measures of mood and health in pregnant women with depressive symptoms, compared to group-based education workshops.
Gender:
Female
Ages:
18 years and above
Trial Updated:
10/10/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Depression
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Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
NCT00024635
Recruiting
The purpose of this protocol is to allow for the careful screening of patients and healthy volunteers for participation in research protocols in the Experimental Therapeutics and Pathophysiology Lab (ETPB) at the National Institute of Mental Health (NIMH) and for the collection of natural history data. In addition the protocol will allow clinicians to gain more experience in the use of a variety of polysomnographic and high-density EEG recordings. Subjects in this protocol will undergo an evalua... Read More
Gender:
All
Ages:
Between 3 years and 99 years
Trial Updated:
06/21/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Depression, Mood Disorders, Anxiety Disorders, Healthy Volunteers, Bipolar Disorder
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Mindfulness Engaged Neurostimulation for Depression
NCT06399406
Recruiting
Repetitive Transcranial Magnetic stimulation (rTMS) is an FDA-approved therapy for treatment resistant depression (TRD) that involves brief magnetic stimulation pulses on the dorsolateral prefrontal cortex (DLPFC) brain region. But studies of rTMS alone show remission rates of ~30%. Additionally, rTMS has not been shown to improve cognitive functioning that may be an independent factor predicting treatment success. This study will develop a novel multimodal treatment, which combines intermittent... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/20/2024
Locations: University of California San Diego, La Jolla, California
Conditions: Depression, Treatment Resistant Depression, Major Depressive Disorder, Depressive Disorder
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Telehealth Behavioral Activation for Teens
NCT06273995
Recruiting
Behavioral activation is one such empirically supported intervention. Derived from cognitive-behavioral therapy, a well-established treatment for depression, behavioral activation uses psychoeducation and skill-building to increase an individual's engagement in valued and enjoyable activities (e.g., socializing with family and friends, exercising, participating in a hobby) in order to improve depressive symptoms. Research has shown that behavioral activation is an effective intervention for depr... Read More
Gender:
All
Ages:
Between 12 years and 18 years
Trial Updated:
06/20/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Depression, Suicide and Self-harm, Depression in Adolescence, Depression Mild, Depression Moderate, Depression Severe
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Long-term Observation of Participants With Mood Disorders
NCT04877977
Recruiting
Background: More than 12,000 people have taken part in research at the Experimental Therapeutics & Pathophysiology Branch at the National Institute of Mental Health Intramural Program. This has led to advances in the treatment of depression, bipolar disorder, and suicide risk. Researchers want to follow up with this group to see if they continue to have mental health symptoms and receive psychiatric treatments. Objective: To learn the long-term impact of depression, bipolar disorder, and suic... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
06/19/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Depression, Suicide Risk
Register for Updates
Healthy Minds Comparison Study
NCT06282523
Recruiting
The goal of this clinical trial is to understand the difference between two versions of the Healthy Minds application, a digital well-being program. The main question it aims to answer is the differences between versions of the Healthy Minds application and their effects on well-being. Participants will complete an online four-week well-being program and complete surveys sent to their email. Participants can expect to participate in the study for four months.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/19/2024
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Depression, Anxiety, Depression/Anxiety
Register for Updates
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
NCT04777357
Recruiting
Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States. The treatment of the depressive episodes of bipolar disorder in the pediatric population has not been as widely studied as the treatment of depressive episodes in bipolar disorder in adults, therefore pharmacotherapeutic options are limited. Given the change in disease state and safety demonstrated in adults with depressive episodes associate... Read More
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
06/18/2024
Locations: Pillar Clinical Research /ID# 226504, Bentonville, Arkansas +62 locations
Conditions: Depression, Bipolar I Disorder
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Feasibility of a Prenatal Yoga Mobile App in African American Pregnant Women
NCT06353113
Recruiting
The goal of this research is to test if a prenatal yoga app can improve well-being in African American/Black (AA) pregnant women. The main questions it aims to answer are: Is the Down Dog prenatal yoga app feasible for AA pregnant women? How does mental and physical health change after using the Down Dog app for 12-weeks? What cultural adaptations to the Down Dog app are needed? The study lasts for 12 weeks and participants are asked to: do prenatal yoga with the app for at least 20 min/day,... Read More
Gender:
Female
Ages:
Between 18 years and 46 years
Trial Updated:
06/18/2024
Locations: San Diego State University, San Diego, California
Conditions: Pregnancy Related, Mental Health Issue, Discrimination, Racial, Stress, Depression
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HypErthermia as an Additional Treatment for the Biology and Experience of Depression: Study 2
NCT05708976
Recruiting
This randomized two-arm intervention trial administers 8 weekly cognitive behavioral therapy (CBT) sessions and 4 bi-weekly active whole-body hyperthermia (active WBH) sessions or 4 bi-weekly sham WBH sessions to adults aged 18 years or older with major depressive disorder (MDD).
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: University of California San Francisco, San Francisco, California
Conditions: Major Depressive Disorder, Depression
Register for Updates
Mood Lifters for Undergraduates
NCT05684120
Recruiting
Large-scale, effective, low-cost, and evidence-based programs that can nimbly translate new research discoveries into prevention and care for psychosocial-based problems are urgently needed since the vast majority of people who need evidence-based care do not receive it. The purpose of this randomized control trial is to investigate the feasibility and efficacy of a Mood Lifters group template specifically for undergraduate students. Mood Lifters is an effective peer-led program that improves o... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Depression, Anxiety, Mood Disorders, Mental Health Wellness 1, Stress
Register for Updates