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Depression Clinical Trials
A listing of 267 Depression clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
241 - 252 of 267
There are currently 267 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Texas.
Featured Trial
Studying an Investigational Drug as Additional Therapy Treatment for Depression
Recruiting
This phase 2/3 study aims to assess the safety and effectiveness of an investigational drug (SEP-363856) as an additional treatment for adults with Major Depressive Disorder and who have not had success with antidepressants in treating their depression symptoms. This study may be suitable for you if you have been diagnosed with depression and your previous antidepressant treatments have not been effective. Should you express interest, the research site will contact you directly to provide further details and address any questions you may have about study requirements, risks/benefits, and compensation.
Conditions:
Depression
Depressive disorder
All Conditions
Featured Trial
Narcolepsy Clinical Study
Recruiting
The Vibrance Studies are researching the safety and effectiveness of a once-daily oral investigational study drug and how it may work in adults 18–70 years of age for the potential treatment of excessive daytime sleepiness (EDS) symptoms in adults with narcolepsy type 1 (NT1) or narcolepsy type 2 (NT2).
All participants who qualify will receive the study drug or placebo (a tablet that looks like the study drug but contains no active medicine), as well as study-related procedures and study-related laboratory tests at no cost. Compensation for time and travel may also be available.
All participants who qualify will receive the study drug or placebo (a tablet that looks like the study drug but contains no active medicine), as well as study-related procedures and study-related laboratory tests at no cost. Compensation for time and travel may also be available.
Conditions:
Narcolepsy
Narcolepsy With Cataplexy
Narcolepsy Without Cataplexy
Narcolepsy 1
Narcolepsy Type 1
Featured Trial
High Triglyceride Clinical Research Study
Recruiting
Living with high triglycerides? See if our clinical study is right for you.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Conditions:
High Triglycerides
High Triglyceride Level
Hypertriglyceridemia
Elevated Triglycerides
Triglycerides High
Featured Trial
Studying an Investigational Medication's Impact on Cardiovascular Events
Recruiting
The main objectives of this Phase 3 study are to evaluate the safety and effectiveness of an investigational medication's ability to reduce major adverse cardiovascular events (such as heart attacks and strokes) in adults at risk. Participants will be randomly assigned to receive either the investigational medication or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
All Conditions
Hyperlipidemia
Cardiovascular Disease
Ischemic heart disease (IHD)
Stroke
Transdiagnostic Individual Behavioral Activation and Exposure Therapy
Recruiting
The Overall Aim of the this project is to compare treatment outcomes and change in putative treatment mediators in Individual Behavioral Activation Therapy (IBAT) against two active psychological interventions (Coping Cat, PASCET) and a wait-list control. Participants will be 200 youth (ages 9-17) diagnosed with a principal anxiety or depression disorder and their caregivers.
Gender:
All
Ages:
Between 9 years and 17 years
Trial Updated:
11/15/2023
Locations: Youth Anxiety and Depression Clinic, Piscataway, New Jersey
Conditions: Anxiety Disorders, Depression
Comparing Targets of Expressive Writing
Recruiting
Expressive writing (Pennebaker & Beall, 1986) involves writing about one's deepest thoughts and feelings surrounding an emotional event. The current literature on the efficacy of expressive writing is mixed and warrants further investigation into how, when, and for whom expressive writing is an effective intervention. The goal of this study is to compare the efficacy of expressive writing interventions in young adults when people imagine that they're writing to themselves vs. a loved one. Partic... Read More
Gender:
All
Ages:
Between 18 years and 25 years
Trial Updated:
11/06/2023
Locations: Peretsman Scully Hall, Princeton, New Jersey
NeuroGlove Anxiety and Depression Study
Recruiting
This is a prospective, homebased, interventional clinical study containing 10 subjects who will be enrolled. Approximately 10 (10) subjects with active anxiety and depression symptoms will receive treatment using the NeuroGlove.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
11/03/2023
Locations: NeuroGlove, Minneapolis, Minnesota
Strengthening Community Mental Health
Recruiting
The goal of this clinical trial is to examine the impact of the Communities Organizing for Power through Empathy (COPE) intervention in adults in communities having recently experienced or at risk of experiencing disaster. The main questions it aims to answer are:
How does the COPE intervention affect individual mental health?
How does the COPE intervention affect protective factors like coping and social support?
How does the COPE intervention affect community resilience?
How does delivery of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: Together Baton Rouge, Baton Rouge, Louisiana
Conditions: Mental Health, Emotional Wellbeing, Anxiety, Depression, Stress, Coping, Perceived Stress, Perceived Social Support
A Precision Medicine Approach to Target Engagement for Emotion Regulation
Recruiting
The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity. Second, using data from an initial sample, the investigators will prospectively assign an independent sample of participants to receive their predicted optimal or non-optimal skills to determine if it is feasible and efficacious to match participants to the most appropriate training condition. Results of these... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/29/2023
Locations: University of Kentucky, Lexington, Kentucky
Conditions: Emotional Regulation, Depression, Anxiety, Borderline Personality Disorder, Obsessive-Compulsive Disorder, Posttraumatic Stress Disorder, Eating Disorders
A Behavioral Activation Prenatal and Postpartum Intervention for Depressed Pregnant Smokers
Recruiting
This study evaluates a mood management and health and wellness smoking cessation intervention for depressed pregnant smokers during and after birth. This study may help pregnant smokers who are experiencing depression quit smoking and stay smoke-free after their babies are born.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/12/2023
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Depression, Tobacco Use Disorder
Improving Adherence to Homework During Therapy
Recruiting
The purpose of this study is to expand Adhere.ly- a simple, HIPAA-compliant, web-based platform to help therapists engage clients in practicing therapeutic skills between sessions (homework) during mental health treatment by conducting a trial comparing standard therapy to therapy enhanced with Adhere.ly.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/15/2023
Locations: University of South Florida, Tampa, Florida
Changes in Brain Function Through Repeated Emotion Regulation Training
Recruiting
This is a pilot study that will investigate how two psychotherapies (re-interpretation and mindfulness) alter brain function. This information will be used to gain understanding of how repeated emotion regulation practices influence the brain and to develop a focused, tactic-based emotional regulation remediation approach for treatment of ADHD.
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
07/31/2023
Locations: Institute of Living/Hartford Hospital, Hartford, Connecticut
Conditions: Depression
Depression and Driving
Recruiting
This project will assess how depression, preclinical AD, and antidepressants affect driving behavior in cognitively normal older adults (65 years).
Gender:
All
Ages:
65 years and above
Trial Updated:
07/24/2023
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Depression, Drive
A Behavioral Activation Intervention Administered in a College Freshman Orientation Course
Recruiting
The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use. Although risky drinking is a common problem among freshmen, engagement in treatment services is very low. The proposed study will test a behavioral activation intervention that addresses factors limiting participation in standard treatment services by targeting alcohol use indirectly, by directly addressing concerns most relevant to incoming college freshmen, and by... Read More
Gender:
All
Ages:
17 years and above
Trial Updated:
07/21/2023
Locations: University of Kansas, Lawrence, Kansas
The Network Study: Soldiers Connecting for Work and Health
Recruiting
This study will examine the efficacy of an internet-based brief intervention designed to reduce risky behavior in Soldiers as they transition from Active Duty into the civilian workforce as a Veteran. Up to 700 soldiers intending to separate from the Army will be recruited, with the intention of drawing a final sample of 450 participants. Study participants will be randomly assigned to either the intervention or the control group, stratified by age and gender.
Gender:
All
Ages:
Between 18 years and 62 years
Trial Updated:
05/24/2023
Locations: Joint Base Lewis-McChord, Tacoma, Washington
Conditions: Alcohol Use Disorder, Depression
Affect Treatment for Depression and Anxiety
Recruiting
The purpose of this study is to evaluate the efficacy and mediators of change in Positive Affect Treatment, a psychotherapy specifically aimed at enhancing reward sensitivity in individuals with low positive affect (a core feature of anhedonia) in the context of depression or anxiety.
Target enrollment is 100 male and female participants with low positive affect and depression or anxiety and impaired functioning, between the ages of 18 and 65 years, who will be randomized to either Positive Aff... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/08/2023
Locations: University of California, Los Angeles, Los Angeles, California +1 locations
Conditions: Depression, Anxiety
241 - 252 of 267