There are currently 254 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Pennsylvania.
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Recruiting
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Gender:
ALL
Ages:
Between 12 years and 20 years
Trial Updated:
10/23/2024
Locations: El Monte High School, El Monte, California +20 locations
Conditions: Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior, Sexual Minority Stress, Suicidality, Substance Use, Bullying, Harassment
Exploring Virtual Reality Adventure Training Exergaming
Recruiting
The current project aims to design and implement an 8-week Virtual Reality Adventure Therapy Exergaming (V-RATE) intervention focused on women veterans. A randomized controlled trial using a repeated measure design with a 1-month follow-up assessment will be employed to examine effects on physical and mental health outcomes.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
10/23/2024
Locations: University of Texas at Arlington, Arlington, Texas
Conditions: Physical Activity, Sedentary Behavior, Depression, Cognitive Function, Post Traumatic Stress Disorder, Quality of Life, Anxiety
The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic
Recruiting
The goal of this clinical trial is to test the effectiveness and implementation of delivering Enhanced Brief Interpersonal Psychotherapy (IPT-B), an evidence-based maternal depression treatment, to mothers of children aged 4-11 years in an urban pediatric asthma clinic. Researchers will compare Enhanced IPT-B and supplemented usual care (brief care coordination). The main questions the trial aims to answer are: 1. Does Enhanced IPT-B decrease maternal depressive symptoms? 2. Does Enhanced IPT-B... Read More
Gender:
ALL
Ages:
4 years and above
Trial Updated:
10/21/2024
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Asthma in Children, Depression
Evaluating Procedures for a Study of the AYA Survivors Coping and Emotional Needs Toolkit
Recruiting
The investigators developed a digital intervention that aims to help adolescent and young adult cancer survivors (AYAs) manage symptoms of depression. This tool includes daily mood tracking, a psychoeducational module about cancer and depression, four components that are based on evidence-based interventions for depression. The goal of this study is to evaluate the acceptability of procedures for a future trial in which the investigators will test which component or combination of components mea... Read More
Gender:
ALL
Ages:
Between 15 years and 39 years
Trial Updated:
10/16/2024
Locations: East Carolina University, Greenville, North Carolina
Conditions: Depression, Cancer, Adolescent, Young Adult, Adult
Mindful Moms Randomized Control Trial
Recruiting
The purpose of this study is to test whether a program called "Mindful Moms" can be helpful for specific measures of mood and health in pregnant women with depressive symptoms, compared to group-based education workshops.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/11/2024
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Depression
Lay-Delivered Behavioral Activation in Senior Centers
Recruiting
In response to large numbers of senior center clients who suffer untreated depression and the dearth of geriatric mental health providers, the investigators have simplified Behavioral Activation to be delivered by lay volunteers ("Do More, Feel Better"; DMFB). The focus of Behavioral Activation is to guide clients to reengage in daily pleasant and rewarding activities, and reduce depressive symptoms. If the investigators can show that the lay delivery model has positive impact in comparison to M... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
10/10/2024
Locations: Brandon Senior Center, Brandon, Florida +24 locations
Conditions: Depression
Testing FIRST in Youth Outpatient Psychotherapy
Recruiting
The study will compare the impact FIRST (a transdiagnostic treatment built upon five empirically supported principles of change) versus usual care outpatient psychotherapy on youths' mental health outcomes and a candidate mechanism of change: regulation of negative emotions.
Gender:
ALL
Ages:
Between 7 years and 15 years
Trial Updated:
10/08/2024
Locations: Harvard University, Cambridge, Massachusetts +1 locations
Conditions: Anxiety, Depression, Trauma, Behavior Problem
Digital Single Session Intervention for Youth Mental Health
Recruiting
The aim of this study is to test the effectiveness of a single-session, digital intervention teaching the principle of practicing the opposite, when administered to youths on the waitlist for psychotherapy, with usual waitlist procedures as a control condition.
Gender:
ALL
Ages:
Between 9 years and 17 years
Trial Updated:
10/03/2024
Locations: Riley Child Psychiatry and Behavioral Sciences Clinic, Indianapolis, Indiana +4 locations
Conditions: Anxiety, Depression, Conduct Disorder, Stress
Diet and Depression
Recruiting
This study is a pilot open label crossover trial to assess the feasibility and acceptability of reducing ultra- processed foods (UPF) in a personalized manner from the diets of patients with major depressive disorder who eat a large percentage of UPF.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/30/2024
Locations: University of California, San Francisco, San Francisco, California
Conditions: Depression, Major Depressive Disorder, Weight Gain, Obesity, Metabolic Syndrome
FMRI Accelerated TMS Depression
Recruiting
This study aims to investigate whether phenotypic-related brain states revealed by a novel INSCAPE ("Individualized Network-based Single-frame Coactivation Pattern Estimation") neuroimaging method in Major Depressive Disorder (MDD) patients can track brain recovery of MDD patients over an accelerated antidepressant transcranial magnetic stimulation (TMS) treatment.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/26/2024
Locations: 30 Bee Street, Charleston, South Carolina
Conditions: Depression
Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department
Recruiting
There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED). Investigators aim to trial low-dose, intravenous ketamine, a drug with well-established use in treatment-resistant depression, for patients who present to the ED with suicidal ideation.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/25/2024
Locations: University of Kansas Strawberry Hill Campus, Kansas City, Kansas +1 locations
Conditions: Suicide, Suicidal Ideation, Depression
Tele-PROTECT Therapy: Effectiveness, Empowerment, and Implementation
Recruiting
The purpose of this randomized trial is to conduct a fully powered effectiveness trial of video-delivered PROTECT (Tele-PROTECT) compared to a video-delivered depression education (DepEd) control condition to be delivered to 140 English- and Spanish-speaking NYC elder abuse victims. Investigators hypothesize three main aims: 1. Effectiveness Aim: Tele-PROTECT participants will have significantly greater and clinically meaningful reductions in depression when compared to the DepEd control; 2. Ab... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
09/19/2024
Locations: Weill Cornell Medicine, New York, New York
Conditions: Depression, Elder Abuse