There are currently 281 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Pennsylvania.
Prevention of Anhedonia in Children
NCT05988138
Recruiting
This trial will test the effects of a positive emotion-focused preventive intervention on reward responsiveness in children of mothers with histories of depression and anhedonia.
Gender:
All
Ages:
Between 8 years and 12 years
Trial Updated:
11/13/2023
Locations: Jesup/Hobbs Building, Nashville, Tennessee
Conditions: Anhedonia, Depression
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Kind Minds Program for Youth With Anxiety and Depression
NCT05353751
Recruiting
Rates of anxiety and depression in youth are substantial, causing a major unmet need for effective interventions. Participation in mindfulness interventions has been demonstrated to reduce anxiety and depressive symptoms among teenagers. Parents' participation in mindfulness interventions has also been shown to reduce their children's mental health symptoms. However, there is no available evidence regarding potential additional benefits for adolescents' mental health of having both the adolescen... Read More
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
11/08/2023
Locations: Imperial High School, Imperial, California
Conditions: Child Anxiety, Depression
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Preventing Persistent Post-Surgical Pain and Dysfunction
NCT03965897
Recruiting
Primary Aim: To examine the superior efficacy of ACT versus Attention Control (AC) on postoperative pain intensity and functioning in at-risk Veterans undergoing TKA. Changes in pain intensity and functioning from baseline to 6 weeks, 3 months and 6 months post-TKA will be compared. Level of pain intensity will be measured using the BPI Pain Severity Subscale and level of functioning will be measured using the KOOS Activities of Daily Living and Quality Of Life Subscales. Secondary Aims: A) To... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/08/2023
Locations: Iowa City VAMC, Iowa City, Iowa
Conditions: Pain, Function, Anxiety, Depression, Arthroplasty, Replacement, Knee, Veterans
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Comparing Targets of Expressive Writing
NCT06130020
Recruiting
Expressive writing (Pennebaker & Beall, 1986) involves writing about one's deepest thoughts and feelings surrounding an emotional event. The current literature on the efficacy of expressive writing is mixed and warrants further investigation into how, when, and for whom expressive writing is an effective intervention. The goal of this study is to compare the efficacy of expressive writing interventions in young adults when people imagine that they're writing to themselves vs. a loved one. Partic... Read More
Gender:
All
Ages:
Between 18 years and 25 years
Trial Updated:
11/06/2023
Locations: Peretsman Scully Hall, Princeton, New Jersey
Conditions: Healthy, Anxiety, Depression
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Wraparound for High-risk Families With Substance Use Disorders: Examining Family, Child, and Parent Outcomes
NCT04637581
Recruiting
The investigators propose a Hybrid Type 1 effectiveness-implementation quasi-experimental trial. Participants are drawn from two different communities contemporaneously. The intervention participants in one community receive a Wraparound intervention. Comparison group participants drawn from a second matched community receive treatment as usual. With this design, the investigators aim to study outcomes associated with the intervention as well as explore important facilitators and barriers associ... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/06/2023
Locations: Dept of Children Youth and Families, Claremont, New Hampshire +3 locations
Conditions: Substance-Related Disorders, Depression, Stress Disorders, Post-Traumatic, Child Abuse, Child Neglect
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NeuroGlove Anxiety and Depression Study
NCT06065787
Recruiting
This is a prospective, homebased, interventional clinical study containing 10 subjects who will be enrolled. Approximately 10 (10) subjects with active anxiety and depression symptoms will receive treatment using the NeuroGlove.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
11/03/2023
Locations: NeuroGlove, Minneapolis, Minnesota
Conditions: Anxiety, Depression, Anxiety Depression, Depression, Anxiety
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SOVA Ambassadors Community Setting
NCT06066697
Recruiting
The purpose of this study is to examine participant adherence to intervention feasibility and acceptability of intervention, attention control, and implementation strategy.
Gender:
All
Ages:
Between 14 years and 21 years
Trial Updated:
11/03/2023
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Depression
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Mood and Thought Process Study
NCT05585775
Recruiting
The primary objective for this project is to test whether affective executive functioning is a mechanism of action of mindfulness-based cognitive therapy and Wellness for Wellbeing. The main questions it aims to answer are: Test the effect of MBCT vs. Wellness for Wellbeing on affective inhibition (i.e., emotionally valenced inhibition as measured via the affective Go/No Go task) using an RCT. Test the effect of MBCT vs. Wellness for Wellbeing on (a) affective updating and (b) affective shiftin... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/02/2023
Locations: Butler Hospital, Providence, Rhode Island
Conditions: Depression in Remission, Depressive Symptoms, Depression
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MBCT Intervention: Healthy Mind, Healthy Living
NCT05965349
Recruiting
Depression among older Korean Americans are rising. Mindfulness-based cognitive therapy (MBCT) is an evidence-based intervention (EBI), effective for preventing depression relapse and reducing depressive symptoms. To enhance feasibility, acceptability, and reach, a brief version of MBCT has been developed and delivered by telephone (brief MBCT-T), but has only been tested in primarily White samples. This study will test test the effect of brief MBCT-T among older Korean Americans.
Gender:
All
Ages:
Between 50 years and 89 years
Trial Updated:
11/01/2023
Locations: University of Washington, Seattle, Washington
Conditions: Mindfulness Based Cognitive Therapy, Depression, Sleep, Anxiety Depression
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Preventing Anxiety and Depression in Older Hispanics
NCT03870360
Recruiting
The purpose of this study is to look at the best ways to prevent anxiety and depression in older Latino adults who are at risk for developing anxiety and depression. Participants will be randomized to either a health promotion intervention or a healthy lifestyles education program.
Gender:
All
Ages:
60 years and above
Trial Updated:
10/30/2023
Locations: University of Miami, Miami, Florida
Conditions: Depression, Anxiety
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Adolescent Attention to Emotion Study
NCT04105868
Recruiting
Rates of depression increase rapidly during adolescence, especially for girls, and, thus, research is needed to spur the development of novel interventions to prevent adolescent depression. This project seeks to determine if a novel visuocortical probe of affect-biased attention (i.e., steady-state visual evoked potentials derived from EEG) can 1) be used to prospectively predict depression using a multi-wave repeated measures design and 2) modify affect-biased attention and buffer subsequent mo... Read More
Gender:
Female
Ages:
Between 13 years and 15 years
Trial Updated:
10/30/2023
Locations: Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania
Conditions: Depression
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Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents
NCT05437588
Recruiting
This study is dedicated to help identify biomarkers for depression and suicide. The purpose of the study is to better understand these links to improve medical and psychiatric care in the future. This research is also to test the effects of standard treatment of depression on improvement in depressive and suicidal behavior and on biomarkers (e.g. miRNA) for these disorders.
Gender:
All
Ages:
Between 10 years and 24 years
Trial Updated:
10/27/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama +1 locations
Conditions: Major Depressive Disorder, Suicidal Ideas, Suicide, Attempted, MDD, Depression, Depression, Teen, Depression and Suicide, Depression in Adolescence, Suicide
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