There are currently 281 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Pennsylvania.
Enhancing Purpose and Well-Being Through a Volunteering Experience Connecting Veterans With English Language Learners
NCT06324383
Recruiting
The goal of this study is to refine and test a strategy for engaging Veterans with symptoms of depression, anxiety, and/or PTSD (Post Traumatic Stress Disorder) as volunteers to help English language learners (ELLs) improve their speaking skills via structured conversations using videoconferencing.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: Center for Clinical Management Research (CCMR), North Campus Research Complex, Ann Arbor, Michigan
Conditions: Depression, Anxiety, Post Traumatic Stress Disorder
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Personalized Depression Treatment Supported by Mobile Sensor Analytics
NCT06292221
Recruiting
The current best practice guidelines for treating depression call for close monitoring of patients, and periodically adjusting treatment as needed. This present study seeks to develop and investigate an innovative digital system, DepWatch, that leverages mobile health technologies and machine learning tools to provide clinicians objective, accurate, and timely assessment of depression symptoms to assist with their clinical decision making process. Specifically, DepWatch collects sensory data pas... Read More
Gender:
All
Ages:
All
Trial Updated:
05/02/2024
Locations: University of Connecticut Health Center, Farmington, Connecticut
Conditions: Depression
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Reducing Depression Self-stigma and Increasing Treatment Seeking Intentions Among Youth
NCT06172075
Recruiting
Young people with depression, especially those of underserved minority groups, avoid treatment due to stigma and discrimination. Social contact is a form of interpersonal contact with members of the stigmatized group and the most effective type of intervention for improvement in stigma-related knowledge and attitudes. In a prior study, the investigators developed short video interventions to reduce stigma and increase treatment seeking among people with depression. The videos vary by protagonis... Read More
Gender:
All
Ages:
Between 18 years and 25 years
Trial Updated:
05/01/2024
Locations: New York State Psychiatric Institute, New York, New York
Conditions: Stigma, Social, Mental Health Disorder, Depression
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Depression Screening in Black Churches
NCT04524767
Recruiting
The overall aim of this study is to employ Community Health Workers (CHWs) to screen for depression in 30 Black churches and compare the effectiveness of Screening, Brief Intervention, and Referral to Treatment (SBIRT) (Intervention arm) to Referral As Usual (Control arm) on treatment engagement for depression. The investigators will assess patient-level outcomes (Mental-Health Related Quality of Life and depressive symptoms) at 3- and 6-months post-screening and conduct a mixed-methods process... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2024
Locations: Columbia University Irving Medical Center Center, New York, New York
Conditions: Depression
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REstoring Mental Health After SARS-CoV-2 Through commUnity-based Psychological Services in New York City
NCT04913766
Recruiting
The goal is to improve mental health of minority and other vulnerable populations disproportionately affected by SARS-CoV-2. The study will evaluate the impact of mental health services on SARS-CoV-2 mitigation strategies such as prevention behaviors, receiving vaccinations, and safe healthcare utilization. Successful completion of this study will contribute to the National Institute of Mental Health Strategic Plan employing implementation science to maximize the public health impact of research... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: New School, New York, New York
Conditions: Depression, Anxiety, Psychological Distress, PTSD
Register for Updates
Acceptance and Commitment Therapy for Depressed People With Spinal Cord Injuries
NCT06233656
Recruiting
Living with spinal cord injury (SCI) can have a significant negative impact on an individual's mental health and restrict participation in personally valued activities and roles. Acceptance and commitment therapy (ACT) is an evidence-based approach that can lessen symptoms of mental health disorders (e.g., depressive symptoms) and improve quality of life through mindfulness and acceptance processes and behavior change processes for valued living. Evidence for ACT for individuals living with SCI,... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Depression, Spinal Cord Injuries
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Geolocation Positional System (GPS) Experience
NCT05991713
Recruiting
The purpose of this study is to use smartphone technology to capture individual location emotional and cognitive data, to examine how real-world behaviors thoughts, emotions, and brain activity are related to one another.
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
04/29/2024
Locations: University of Miami, Coral Gables, Florida
Conditions: Emotions, Anhedonia, Depression
Register for Updates
Reaching Out to Distressed Medical Residents, Fellows and Faculty
NCT02010866
Recruiting
The purpose of this study is to study whether distressed medical residents, fellows, and faculty health professionals benefit from completing online an anonymous and interactive screening of stress, depression, substance use, and suicidal thoughts. The screening and ability to interact online with a clinician anonymously are hypothesized to increase willingness to come for counseling in person. Suicide risk factors are expected to be lower once the distressed medical trainee or faculty member re... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/27/2024
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Depression, Suicide
Register for Updates
Investigating Dynamic Interactions in Distributed Cognitive Control Networks
NCT05927974
Recruiting
The purpose of this study is to investigate the brain activity associated with cognitive tasks (thinking, reasoning, remembering) in order to understand how the brain works during certain tasks and to improve treatment for diseases like dementia and attention deficit disorders. Cognitive (thinking) impairment may include poor memory function, poor attention span, or psychiatric disorders (ex: ADD, depression). The investigators are interested in the brain activity related to these issues, and wa... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/24/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cognitive Impairment, Dementia, ADD, Depression
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Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department
NCT06085937
Recruiting
There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED). Investigators aim to trial low-dose, intravenous ketamine, a drug with well-established use in treatment-resistant depression, for patients who present to the ED with suicidal ideation.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/23/2024
Locations: University of Kansas Strawberry Hill Campus, Kansas City, Kansas +1 locations
Conditions: Suicide, Suicidal Ideation, Depression
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Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
NCT06374277
Recruiting
Socioeconomically disadvantaged populations with multiple chronic conditions have high rates of nonadherence to essential chronic disease medications after hospital discharge. Medication nonadherence after hospital discharge is significantly associated with increased mortality and higher rates of readmissions and costs among these patients. Major patient-reported barriers to essential medication use after hospital discharge among low-income individuals are related to social determinants of healt... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: University of Tennessee Medical Center, Knoxville, Tennessee +1 locations
Conditions: Diabetes, Hypertension, High Cholesterol/Hyperlipidemia, Coronary Artery Disease, Congestive Heart Failure, Chronic Lung Disease, Chronic Kidney Diseases, Arrythmia, Stroke, Depression, Anxiety, Pulmonary Embolism, Heart Attack
Register for Updates
A Neuroimaging Study of Open-label Placebo in Depressed Adolescents
NCT04201106
Recruiting
Major depressive disorder (MDD) is the current leading cause of disability worldwide and adolescence is an especially vulnerable period for the onset of depression. Non-pharmacologic approaches are particularly attractive as treatment of adolescent depression due to the elevated risks of side effects related to the use of psychotropic drugs during development. A recent meta-analysis detected a positive and significant effect of non-deceptive placebos (open-label placebo, OLP) for a series of cli... Read More
Gender:
All
Ages:
Between 13 years and 18 years
Trial Updated:
04/23/2024
Locations: UCSF, San Francisco, California
Conditions: Depression
Register for Updates