There are currently 281 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Autism participants are California, New York, Florida and Pennsylvania.
Positive Suggestions Via MP3 Messages
NCT04437095
Recruiting
The purpose of this study is to assess the use of an audio recording containing positive suggestion as a means to provide needed psychological support to critically ill patients in a feasible and reliable manner.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/12/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Post Intensive Care Unit Syndrome, Psychological Trauma, Anxiety, Depression, PTSD
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Early Life Stress and Depression: Molecular and Functional Imaging
NCT04713722
Recruiting
Severe childhood adversity accounts for a large portion of psychiatric illness, and an increased risk for major depressive disorder (MDD). For some individuals, childhood adversity has negative psychological and medical consequences; others preserve mental and physical health despite such experiences (they are resilient). In spite of this, little is known about the neurobiological mechanisms related to childhood adversity, especially oxidative stress abnormalities in the brain. To fill this gap,... Read More
Gender:
Female
Ages:
Between 20 years and 32 years
Trial Updated:
03/11/2024
Locations: McLean Hospital, Belmont, Massachusetts
Conditions: Depression, Trauma, Psychological
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Testing a Lifestyle Physical Activity Intervention for Women With Depression in Alcohol Treatment
NCT04667520
Recruiting
The primary aim of this project is to test the efficacy of a technology-supported lifestyle physical activity (LPA) intervention for preventing relapse among women with depression engaged in alcohol treatment. Participants are randomized to either 1) LPA+Fitbit intervention or 2) Fitbit Only control condition. Follow-up assessments and EMA data will be collected.
Gender:
Female
Ages:
Between 18 years and 65 years
Trial Updated:
03/11/2024
Locations: Butler Hospital, Providence, Rhode Island
Conditions: Alcohol Use Disorder, Depression
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Testing the Effects of Project Calm in Ukrainian Schools
NCT06217705
Recruiting
The purpose of this study is to test the effectiveness of a universal, digital, single-session intervention for youth mental health, functioning, and well-being, when implemented with Ukrainian children and adolescents. The intervention teaches well-established procedures that research has shown to be effective in helping American children calm themselves and regulate emotions, including slowed breathing and peaceful mental imagery. The intervention has not been tested previously with Ukrainian... Read More
Gender:
All
Ages:
Between 9 years and 18 years
Trial Updated:
03/09/2024
Locations: Harvard University, Cambridge, Massachusetts
Conditions: Trauma, Anxiety, Depression, Child Behavior
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Acceptance and Commitment Therapy for Depressed Individuals Living With Spinal Cord Injury Sustained Within 5 Years
NCT05725161
Recruiting
This randomized controlled trial aims to assess effects of videoconferencing acceptance and commitment therapy (ACT) on mental health outcomes in individuals living with spinal cord injuries (SCI). A total of 40 individuals living with SCI sustained within 5 years and experiencing depressive symptoms will be recruited and randomly assigned to either the ACT group or the wait-list control group. The ACT group will receive 8 weekly individual ACT sessions guided by a coach through videoconferencin... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/05/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Depression, Spinal Cord Injuries
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Evaluation of a Proactive Identification and Digital Mental Health Intervention Approach to Address Unmet Psychosocial Needs of Individuals Living With Cancer
NCT05932810
Recruiting
The purpose of this research study is to evaluate a mobile application (app) for depression treatment called "Moodivate" among cancer survivors. Moodivate was developed by the investigators to assist with the treatment of depressed mood. Participants will be randomly assigned to either download the mobile app, "Moodivate", or not. Approximately 2/3 of participants enrolled will receive the mobile app and the remaining 1/3 will not. All participants will complete electronic questionnaire measur... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Depression, Depressive Symptoms, Cancer
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Neural Circuit Biomarkers of Transcranial Magnetic Stimulation Study
NCT04663841
Recruiting
This study is currently recruiting Veterans only. The objective of this observational study is to test whether neuroimaging biomarkers of repetitive transcranial magnetic stimulation (TMS) can be prospectively replicated in a large ecologically valid sample. We focus on cognitive network connectivity as a predictive biomarker of the clinical effect of TMS, and as a response biomarker of change with TMS. We address this objective through a pragmatic approach in which we recruit patients undergoin... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Stanford University Department of Psychiatry, Stanford, California
Conditions: Depression
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A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
NCT04777357
Recruiting
Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States. The treatment of the depressive episodes of bipolar disorder in the pediatric population has not been as widely studied as the treatment of depressive episodes in bipolar disorder in adults, therefore pharmacotherapeutic options are limited. Given the change in disease state and safety demonstrated in adults with depressive episodes associate... Read More
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
03/04/2024
Locations: Pillar Clinical Research /ID# 226504, Bentonville, Arkansas +56 locations
Conditions: Depression, Bipolar I Disorder
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Brief, High-dose rTMS for Depression
NCT04657432
Recruiting
High frequency repetitive transcranial magnetic stimulation (rTMS) has been shown to be safe, feasible, and acceptable. Conventionally, rTMS investigations have relied on rational decision trees for dosage determination. The purpose of this study is to systematically examine an accelerated protocol of intermittent theta burst (iTBS). Study 1 aims to provide a quantifiable dose-response curve for iTBS and depressive symptom reduction in major depression. Study 2 aims to determine the role of indi... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
03/01/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Depression, Anxiety
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Mechanisms of Behavioral Activation (BA)
NCT05548244
Recruiting
The investigators will be comparing brain (neural) activation of depressed adolescent patients before, during and after a course of Behavioral Activation (BA) therapy using functional magnetic resonance imaging (fMRI). In particular, the project seeks to determine whether BA targets different neural mechanisms for behavioral avoidance associated with low motivation as compared to threat avoidance. A group of healthy controls will also be scanned as a comparator group for behavioral and imaging m... Read More
Gender:
All
Ages:
Between 15 years and 17 years
Trial Updated:
02/29/2024
Locations: Emory University, Atlanta, Georgia +2 locations
Conditions: Depression
Register for Updates
Improving Negative Stressful Perseverations in Insomnia to Revitalize Expecting Moms (INSPIRE)
NCT05356364
Recruiting
Nearly half of women develop insomnia during pregnancy, which is associated with increased risk for developing perinatal depression. The purpose of this research is to evaluate the implementability and effectiveness of a mindfulness-based therapy for insomnia relative to cognitive-behavioral therapy for insomnia in pregnant women with insomnia and comorbid depression. The investigators aim to examine whether a mindfulness-based intervention effectiveness reduces symptoms of insomnia and comorbid... Read More
Gender:
Female
Ages:
Between 18 years and 40 years
Trial Updated:
02/29/2024
Locations: Henry Ford Medical Center, Novi, Michigan
Conditions: Insomnia, Depression
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Randomized Controlled Trial of Project Body Neutrality
NCT06172452
Recruiting
This study tests a single-session intervention (SSI) targeting risk factors for depression and eating disorders among sexual and gender minority (SGM) adolescents. Youth ages 13-17 who identify as sexual or gender minorities will be randomized to the intervention condition (Project Body Neutrality SSI) or a control (supportive therapy SSI). Participants will complete questionnaires before the intervention, immediately after the intervention, and 3-months after completing the intervention so that... Read More
Gender:
All
Ages:
Between 13 years and 17 years
Trial Updated:
02/26/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Depression, Eating Disorders, Body Image
Register for Updates