There are currently 281 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Autism participants are California, New York, Florida and Pennsylvania.
Cognitive and Affective Processes Online
NCT05736471
Recruiting
This study will provide data for evaluating the psychometric characteristics of the tests assessing cognitive flexibility, including their (1) internal consistency, (2) feasibility and tolerability, their (3) convergent and discriminant validity of cognitive and affective constructs such as those introduced to understand mental disorders, and (4) sensitivity (and correspondence) to individual differences. For these tests to be useful in studying clinical conditions, they must show adequate relia... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/25/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Depression
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Wellness App for Sleep Disturbance in Hematological Cancer Patients
NCT05294991
Recruiting
In a randomized controlled trial (RCT), the investigators will recruit participants to an 8-week "app-based wellness" intervention, followed by a 12-week follow-up period. The investigators will recruit a total of 276 self-declared Chronic Hematological Cancer (CHC) patients who (representative of age, race/ethnicity, and gender) will be on stable CHC pharmacologic therapy (if any), self-identify as sleep disturbed (>5 on Pittsburgh Sleep Quality Index), do not have a sleep disorder diagnosis, d... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/22/2024
Locations: Arizona State University, Phoenix, Arizona +2 locations
Conditions: Cancer, Sleep Disturbance, Anxiety, Depression, Inflammation, Fatigue
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Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression
NCT06002204
Recruiting
SHAKTI (from the Sanskrit word for "power") is a 5-year natural history, longitudinal, prospective study of a cohort of 6,000 participants that will help uncover the socio-demographic, lifestyle, clinical, psychological, and neurobiological factors that contribute to antidepressant treatment response (remission, recurrence, relapse and individual outcomes in depressive disorders) and resilience. As this is an exploratory study, we will assess a comprehensive panel of carefully selected participa... Read More
Gender:
All
Ages:
10 years and above
Trial Updated:
03/21/2024
Locations: Afrida Khurshid, Dallas, Texas
Conditions: Depression, Treatment Resistant Depression, Mood Disorders, Bipolar Disorder, Mental Disorders, Bipolar and Related Disorders
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Exploring Mechanisms for Neuropsychiatric Symptoms of Parkinson Disease Using Transcranial Direct Current Stimulation
NCT03074812
Recruiting
This study evaluates the effect of transcranial direct current stimulation (tDCS) on non-motor symptoms of Parkinson's disease, including depression and cognitive symptoms. Participants are randomized to receive active or sham tDCS for 30 minutes over 10 treatment sessions.
Gender:
All
Ages:
Between 18 years and 95 years
Trial Updated:
03/20/2024
Locations: Johns Hopkins Hospital / Johns Hopkins University, Baltimore, Maryland
Conditions: Idiopathic Parkinson's Disease, Parkinson Disease, Depression
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Cardiac Markers in Depressed Patients With Coronary Heart Disease - R01HL147862
NCT04682769
Recruiting
Depression doubles the risk of death in patients with coronary heart disease (CHD), but so far, there is insufficient evidence that we can reduce the risk of death by treating depression. This study will investigate the cardiac risk markers that are associated with depression symptoms that remain despite treatment, and identify potential targets for their treatment. The results of the study will inform the development of more effective interventions to improve both depression and survival in pat... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/20/2024
Locations: Washington University, Saint Louis, Missouri
Conditions: Coronary Heart Disease, Depression
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Adapting BA for Minimally Verbal Autistic Adults
NCT06064422
Recruiting
The present study aims to adapt and evaluate the feasibility of the BeatIt-2 behavioral activation intervention for people with intellectual disabilities and low mood to be implemented with minimally verbal autistic individuals.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/20/2024
Locations: Rutgers University - New Brunswick, Piscataway, New Jersey
Conditions: Autism, Depression, Autism Spectrum Disorder With Impaired Functional Language, Autism Spectrum Disorder
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Telehealth Behavioral Activation for Teens
NCT06273995
Recruiting
Behavioral activation is one such empirically supported intervention. Derived from cognitive-behavioral therapy, a well-established treatment for depression, behavioral activation uses psychoeducation and skill-building to increase an individual's engagement in valued and enjoyable activities (e.g., socializing with family and friends, exercising, participating in a hobby) in order to improve depressive symptoms. Research has shown that behavioral activation is an effective intervention for depr... Read More
Gender:
All
Ages:
Between 12 years and 18 years
Trial Updated:
03/18/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Depression, Suicide and Self-harm, Depression in Adolescence, Depression Mild, Depression Moderate, Depression Severe
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Ketamine-assisted Psychotherapy (KAP) for Patients With Existential Distress Associated With Non-operable GI Cancers
NCT06001372
Recruiting
The goal of this open-label clinical trial is to assess the feasibility of Ketamine-assisted psychotherapy (KAP) studies for adults with non-operable GI cancers suffering with existential distress. The main questions it aims to answer are: Is it feasible to conduct a KAP study with this population? What is the safety and tolerability of KAP in this population? How prevalent is existential distress in this population? Participants will undergo KAP administered as standard of care at the HMHI Pa... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: Huntsman Cancer Institute, Salt Lake City, Utah
Conditions: Gastrointestinal Cancer, Depression, Anxiety
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Treatment, Emotion, and Neuromodulation of Depression (TREND) Study
NCT05436379
Recruiting
The investigators will administer theta burst stimulation (TBS) in efforts to observe a decrease in severity of reported depression symptoms. A subset of participants will receive positive affect training during this intervention.
Gender:
All
Ages:
Between 18 years and 26 years
Trial Updated:
03/14/2024
Locations: The University of Pittsburgh, Department of Psychiatry, Pittsburgh, Pennsylvania
Conditions: Depression
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Diet and Depression
NCT06252701
Recruiting
This study is a pilot open label crossover trial to assess the feasibility and acceptability of reducing ultra- processed foods (UPF) in a personalized manner from the diets of patients with major depressive disorder who eat a large percentage of UPF.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
03/14/2024
Locations: University of California, San Francisco, San Francisco, California
Conditions: Depression, Major Depressive Disorder, Weight Gain, Obesity, Metabolic Syndrome
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Transdiagnostic Cognitive Biomarkers
NCT04864080
Recruiting
The overall objective of this study is to determine the feasibility of identifying transdiagnostic biomarkers of cognitive function mediated by neuromodulation of the dorsolateral prefrontal cortex that are translatable across disease groups in order to more accurately phenotype clusters of cognitive dysfunction. Completing behavioral paradigms with electrophysiology and TMS is a challenging frontier. This study focuses on the feasibility of such an endeavor for those with chronic pain or depres... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/13/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Pain, Depression
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Families With Pride ("Familias Con Orgullo").
NCT06057337
Recruiting
This study will evaluate the effects of a parenting intervention for Hispanic sexual minority youth in preventing/reducing drug use and depressive symptoms. It will also examine whether the intervention improves parent social support for the adolescent, parent acceptance, family functioning, and whether it reduces general stress and stress associated with being a Hispanic sexual minority.
Gender:
All
Ages:
Between 13 years and 17 years
Trial Updated:
03/13/2024
Locations: University of Miami, Coral Gables, Florida
Conditions: Depression, Drug Use
Register for Updates