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Massachusetts Paid Clinical Trials
A listing of 3308 clinical trials in Massachusetts actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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Clinical Trial Phase
Massachusetts is currently home to 3308 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Boston, Worcester, Springfield and Burlington. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Clinical Study
Recruiting
We are evaluating an investigational treatment to see if it may help people dealing with chronic cough.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Conditions:
Cough
Chronic Cough
Asthma
Allergic Asthma
Sinusitis
Featured Trial
Transcranial Magnetic Stimulation (TMS) for Obsessive Compulsive Disorder (OCD)
Recruiting
Transcranial magnetic stimulation (TMS) is an FDA-approved, non-invasive form of brain stimulation for OCD. TMS has been shown to be an effective form of treatment in individuals with OCD. By using a form of TMS termed theta-burst stimulation (TBS), we hope that this will result in a more effective treatment by producing faster symptom reduction. We are trialing a novel form of accelerated TMS, where we will deliver ten 10-minute sessions per day, for 5 days. This study will compare the efficacy of TMS for OCD at two distinct brain regions. Participants will be randomized into one of two study groups, and receive stimulation at either the DMPFC or R-OFC. Both regions have been linked to OCD by research. Patients that don't respond to their study region will have the option to receive stimulation at the other region.
Conditions:
Obsessive-Compulsive Disorder
Obsessive Compulsive Disorder
Obsessive Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder (OCD)
Obsessive-compulsive Disorders and Symptoms
Featured Trial
High Triglyceride Clinical Research Study
Recruiting
Living with high triglycerides? See if our clinical study is right for you.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Conditions:
High Triglycerides
High Triglyceride Level
Hypertriglyceridemia
Elevated Triglycerides
Triglycerides High
Featured Trial
Gout Clinical Research Study
Recruiting
Struggling to manage gout flares? Are you familiar with the side effects of urate lowering treatments? You may be able to help our clinical study develop safer and more effective medicines to reduce uric acid and ease inflammation.
Eligible participants will receive study-related medical care at no cost.
Eligible participants will receive study-related medical care at no cost.
Conditions:
Gout
Gout Flare
Acute Gout
Chronic Gout
Gout Attack
Home With TablO outcoMEs (HOME) Registry
Recruiting
Prospective, multicenter, single arm, post-market study to evaluate real world clinical outcomes in ESRD patients receiving in-home dialysis on the Tablo Hemodialysis System.
Gender:
All
Ages:
15 years and above
Trial Updated:
09/22/2022
Locations: Berkshire Medical Center, Pittsfield, Massachusetts
Conditions: End Stage Renal Disease
Indoor Air Quality and Respiratory Morbidity in School-Aged Children With BPD
Recruiting
Investigators want to learn the role of indoor environmental exposures on respiratory symptoms, and, separately, on lung function deficits in school-aged children with bronchopulmonary dysplasia (BPD).
Gender:
All
Ages:
Between 6 years and 12 years
Trial Updated:
09/20/2022
Locations: Boston Childrens Hospital, Boston, Massachusetts
Conditions: Bronchopulmonary Dysplasia, Chronic Lung Disease of Newborn, Environmental Exposure
Pharmacological Activation of HMN for OSA Aim 2
Recruiting
Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. OSA patients show a marked reduction in upper airway (UA) dilator muscle activity at sleep onset and this phenomenon leads to increased collapsibility of UA compared to normal subjects. In this protocol the investigators will test the effect of LTM1201AZ, LTM1201AT, LTM1201AD, LTM1201AG administered before sleep on OSA phenotype traits and OSA severity during sleep.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
09/19/2022
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Obstructive Sleep Apnea
Genes and Environment in Multiple Sclerosis
Recruiting
The purpose of the research study is to identify the genetic, environmental and immune profiles that may increase a person's risk of developing multiple sclerosis (MS). While MS is not a disease caused by a single variation in genetic material (DNA), a single environmental factor, or a single malfunction in immune cells, there are genetic alterations, environmental exposures and immunologic factors that make the development of MS more likely. Obtaining information about who is at risk for MS wil... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/16/2022
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Multiple Sclerosis
Rare and Atypical Diabetes Network
Recruiting
RADIANT is a network of 14 clinical sites and several laboratories dedicated to the study of atypical diabetes.
The objective of this study is to define new forms of diabetes and the unique mechanisms underlying these forms of atypical diabetes. The specific aims are to:
Identify and enroll individuals and families with undiagnosed rare and atypical forms of diabetes.
Determine the etiologic basis of the metabolic disorder among individuals and families with novel forms of rare and atypical di... Read More
Gender:
All
Ages:
All
Trial Updated:
09/14/2022
Locations: Massachusetts General Hospital (MGH), Boston, Massachusetts
Conditions: Diabetes Mellitus, Diabetes Mellitus Progression, Glucose Intolerance, Glucose Metabolism Disorders, Metabolic Disease, Endocrine; Complications, Endocrine System Diseases
Nutrition for Brain and Body Health (BB-Health) Feasibility Trial
Recruiting
The goal of the trial is to determine the feasibility of implementing a specific nutrition regimen used alone or in combination with a behavioral weight loss (WL) intervention on cognition and cerebral blood flow in older adults at risk of cognitive decline.
Gender:
All
Ages:
Between 55 years and 85 years
Trial Updated:
09/13/2022
Locations: Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts
Conditions: Cognition, Obesity
Diagnosis of Alzheimer's Disease Using Event Related Potentials
Recruiting
This study evaluates the use of an EEG device using Event Related Potentials to help diagnose Alzheimer's Disease in the outpatient clinical setting.
Gender:
All
Ages:
Between 50 years and 100 years
Trial Updated:
09/08/2022
Locations: VA Boston Healthcare, Jamaica Plain, Massachusetts
Conditions: Mild Cognitive Impairment
Folfox+Irinotecan+Chemort In Esophageal Cancer
Recruiting
In this research study, is studying how Liposomal Irinotecan in combination with the standard of care interventions FOLFOX, carboplatin paclitaxel, and radiation therapy affect gastroesophageal junction or esophagogastric cancer
This research study involves the following study intervention:
- Liposomal irinotecan
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Gastroesophageal Junction Adenocarcinoma, Esophagogastric Cancer
Electron Beam Intraoperative Radiation Therapy Following Chemoradiation in Patients With Pancreatic Cancer With Vascular Involvement
Recruiting
This research study is studying an intervention as a possible treatment for pancreatic cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Conditions: Pancreas Cancer
Durvalumab (MEDI4736) and Tremelimumab and Radiation Therapy in Hepatocellular Carcinoma and Biliary Tract Cancer
Recruiting
This research study is studying a combination of drugs as a possible treatment for Hepatocellular Carcinoma or Biliary Tract Cancer.
The interventions involved in this study are:
Durvalumab
Tremelimumab
Radiation Therapy
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Hepatocellular Carcinoma, Biliary Tract Cancer
Study of TAS-102 Plus Radiation Therapy for the Treatment of the Liver in Patients With Hepatic Metastases From Colorectal Cancer
Recruiting
This research study is studying a drug in combination with radiation therapy as a possible treatment for hepatic metastases from colorectal cancer.
The interventions involved in this study are:
Trifluridine (TAS-102)
Radiation Therapy
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Colorectal Cancer
Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer
Recruiting
This research study is studying a combination of drugs with radiation therapy as a possible treatment for Microsatellite Stable Colorectal Cancer, Pancreatic Cancer, or MSI High Colorectal Cancer.
The interventions involved in this study are:
Nivolumab
Ipilimumab
Radiation Therapy
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: Massachusetts general Hospital, Boston, Massachusetts