There are currently 228 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
Eccentric Muscle Training, Stimulation, and Biomarkers in SCI
Recruiting
The investigators are studying a new rehabilitation treatment for individuals trying to recover walking after spinal cord injury (SCI). The investigators will test conditions in the blood and spinal fluid to determine the best time to start this new training program. This will include checking for certain features called biomarkers by testing participants' spinal fluid and blood and compare these features to individuals without SCI. These features will help investigators determine when to start... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
12/19/2023
Locations: The Ohio State University, Columbus, Ohio +1 locations
Conditions: Spinal Cord Injuries, Healthy
Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT)
Recruiting
This is a single-center study at the Cleveland Clinic Main Campus designed to study biomarkers in healthy individuals to identify novel mechanisms of platelet activation and how platelets drive vascular inflammation and thrombosis in diseases.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/24/2023
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Healthy
Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria
Recruiting
This Phase 1, first-in-human, randomized, double-blinded, placebo controlled study is evaluating FB-001 in healthy volunteers (Part 1) and participants diagnosed with enteric hyperoxaluria (Part 2). Eligible participants receive investigational product and undergo safety monitoring, evaluations and subsequent follow-up after investigational product administration.
Gender:
All
Ages:
Between 18 years and 74 years
Trial Updated:
01/23/2023
Locations: Medpace Clinical Pharmacology Unit, Cincinnati, Ohio
Conditions: Healthy, Enteric Hyperoxaluria
Clinical Performance Testing of Philips FAST SpO2 With Masimo Pulse Oximetry Sensors Across Skin Pigmentation
Recruiting
Validate the performance of Philips FAST SpO2 with Masimo Pulse Oximetry Sensors in determining functional arterial oxygen saturation (SpO2) using arterial saturation (SaO2) as a reference in the range of 70-100% in subjects of varying skin pigmentation.
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
05/15/2024
Locations: Masimo Corporation, Irvine, California
Conditions: Healthy
Study of New Magnetic Resonance Imaging Methods of the Brain
Recruiting
The purpose of this investigation is to develop improved magnetic resonance imaging (MRI) techniques and hardware for studying brain function. MRI is a diagnostic tool that provides information about brain chemistry and physiology. This study will evaluate new MRI methods for monitoring blood flow to regions of the brain in response to simple tasks. The MRI machine used in this study is more powerful than those in most hospitals, permitting a higher visual resolution. Normal healthy volunteers... Read More
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
05/14/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy, Magnetic Resonance Imaging, Adult, Brain Mapping, fMRI, Healthy Volunteer
Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung
Recruiting
Background: Tuberculosis (TB) is a lung disease. It is caused by inhaling a type of airborne bacterium. Tuberculin Purified Protein Derivative (PPD) is used to test for TB exposure. It is usually injected under a person s skin. In this study, it will be applied in the lung. Objective: To learn how the cells within the lung react (immune response) when exposed to PPD. Eligibility: Adults ages 18-64 who (1) have been exposed to TB but do not have active disease or symptoms or (2) have never b... Read More
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
05/14/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy, Latent Tuberculosis Infection (LTBI)
Imaging Techniques in MRI
Recruiting
Background: - Magnetic resonance imaging (MRI) scans must be performed according to specified sets of parameters that provide optimal images of each organ and each area of the body. These scanning parameters are often specific to the institution or organization at which they are employed, and may also depend on the manufacturer of the MRI scanning equipment. Because MRI scanning equipment is always being updated and upgraded, researchers are interested in developing new and optimized scanning p... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
05/14/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Cardiac Risk Factors, Healthy, Healthy Volunteers
The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation
Recruiting
the purpose of this experiment is to determine if acute melatonin supplementation alters central and peripheral cardiovascular responses to a cold pressor test at rest and during dynamic exercise.
Gender:
All
Ages:
Between 18 years and 35 years
Trial Updated:
05/09/2024
Locations: Department of Health and Exercise Science, Norman, Oklahoma
Conditions: Healthy
A Study to Assess LY4100511 (DC-853) in Healthy Adult Participants
Recruiting
The main purpose of this study is to assess the effect of multiple doses of itraconazole, fluconazole, and carbamazepine on single dose pharmacokinetic of LY4100511 (DICE-853) in healthy participants. The study will also evaluate the safety and tolerability of LY4100511 (DICE-853) with itraconazole, fluconazole, and carbamazepine.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
05/09/2024
Locations: ICON San Antonio Clinical Research Unit, San Antonio, Texas
Conditions: Healthy
A Study to Evaluate Safety, Tolerability of LY4100511 (DC-853) in Healthy Asian and Non-Asian Participants
Recruiting
The main purpose of this study is to assess the safety and tolerability of LY4100511 (DC-853) after single and multiple dose administrations in healthy asian participants and non-Asian participants. Part A consists of 2 groups and Part B and C include optional groups.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/08/2024
Locations: Altasciences Clinical Los Angeles, Inc, Cypress, California
Conditions: Healthy
Mitochondria (MI) Energy - Linking Bioenergetic Phenotypes in Circulating Cells With Cardiometabolic Health in School-age Children
Recruiting
This research study is about how daily activities, behaviors, and fitness affect the health and function of blood cells and their mitochondria, which are the powerhouses of the cells. These small mitochondria inside the cells make energy, and are very important for the health of the body.
Gender:
All
Ages:
Between 8 years and 10 years
Trial Updated:
05/07/2024
Locations: Arkansas Children's Nutrition Center, Little Rock, Arkansas
Conditions: Healthy
Gut Oxalate Absorption in Calcium Oxalate Stone Disease
Recruiting
The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased absorption of dietary oxalate, which would lead to increased urinary excretion of oxalate. The study will recruit adult patients with a history of calcium oxalate kidney stones and healthy volunteers without kidney stones. Participants will ingest fixed diets containing low and moderately high amounts of oxalate for 5 days at a time ingest a soluble form of oxalate and... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/07/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +1 locations
Conditions: Kidney Stone, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Oxaluria, Healthy