A Guide To Endometriosis

Match to Endometriosis Clinical Trials

What is Endometriosis?

Endometriosis is a disorder in which tissue similar to the uterine lining grows outside the uterus. Tissue can develop in the ovaries, fallopian tubes, or even as far as the intestines. This can cause severe pelvic pain which is often misdiagnosed as period pain.

Endometriosis is very common, with more than 200,000 cases in the U.S. every year. While there are effective treatments, surgery is required to remove existing tissue. Unfortunately, abnormal tissue growth can recur at a future time.

What Conditions Are Associated With Endometriosis?

Endometriosis can develop early and has been found in girls as young as 11. However, it is often not diagnosed until later in life. Endometriosis is commonly discovered between ages 25-35. Often, this requires consultation with several doctors.

Endometriosis is rarest among postmenopausal women and most common among tall and thin women with low Body Mass Index (BMI). Although it does not necessarily cause infertility, it is most common in women who are experiencing infertility.

Most cases are asymptomatic. However, endometriosis symptoms can be debilitating.

The most common symptoms of endometriosis include:

  • Pelvic pain, which may become more intense during menstruation
  • Pain during intercourse
  • Painful urination or bowel movements

Many women do not realize they have endometriosis and receive a diagnosis due to infertility. Endometriosis is challenging to diagnose. It can only be confirmed through surgery – most commonly laproscopy, in which a tiny camera is used to examine organs.

Match to Endometriosis Clinical Trials

Endometriosis Recovery and Lifestyle Change

Endometriosis treatment includes medication and surgery. Medication focuses on pain relief. Surgery can eliminate excess tissue, after which the condition may or may not recur. Recent advances in surgical techniques have reduced the size and depth of incisions needed to treat endometriosis. This results in less surgery pain and a faster recovery.

Endometriosis may interfere with fertility and increase risk during pregnancy. Sufferers who are pregnant or planning to become pregnant often seek care from an ob/gyn early on. This makes a successful pregnancy more likely while protecting the mother’s health.

The cause of endometriosis has not yet been identified. However, those who have had it in the past are at greater risk of a future episode, even if the excess tissue is removed. It is vital for patients to stay in communication with a doctor and seek care if symptoms change.

Endometriosis Medical Research

There is a great deal of endometriosis research still to be done. Recent endometriosis clinical trials have focused on investigational treatments that may inhibit tissue growth and deactivate the chemical signaling mechanisms that promote overgrowth.

Why Are More Endometriosis Clinical Trials Necessary?

Endometriosis clinical trials are essential to understanding the underlying causes of the disease. New clinical resources for endometriosis will require deep investigation of the environmental and genetic factors that may predispose a patient to this condition.

Endometriosis is classified into four stages depending on its severity. Later stages can cause complications due to scarring and tissue implants within the ovaries. Endometriosis clinical trials are also needed to define treatment protocols for each of these stages.

Current Endometriosis Clinical Trials

The following list includes all endometriosis clinical trials reported to ClinicalTrials.gov. To feature an endometriosis clinical trial on our site, contact us.


Reduced diagnosis of endometriosis has led to it remaining a relatively mysterious condition. Millions of women suffer from endometriosis – including those who do not know it yet. With investigational endometriosis treatments, new endometriosis clinical resources may finally be on the way. Any woman who has suffered the disease or has a relative who does has a role to play.

Match to Endometriosis Clinical Trials