What is Fibromyalgia?


ibromyalgia is a common musculoskeletal condition. It causes pervasive muscle pain and tenderness that can appear alongside fatigue and cognitive or mood changes. Pain and spasms may occur virtually anywhere in the body.

The origins of fibromyalgia are not fully understood. Experts believe fibromyalgia amplifies painful sensations by changing how the brain processes them. Once it develops, fibromyalgia generally persists for life, although symptoms may change.

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What Conditions is Fibromyalgia Associated With?

Anyone can develop fibromyalgia, although about 70%-90% of sufferers are women. It is often experienced in the wake of a physical trauma, surgery, infection, or substantial psychological stress. However, it does not always have a triggering event.

Mental health symptoms are commonly experienced alongside fibromyalgia pain. This includes characteristic “fibro fog” that makes it difficult to focus and pay attention. Many fibromyalgia patients also suffer anxiety and depression.

Fibromyalgia Lifestyle Changes and Recovery

There is no cure for fibromyalgia. Fibromyalgia treatment focuses on managing symptoms and maintaining quality of life. Fibromyalgia symptoms do not necessarily worsen with age, but they tend to be pervasive. Fibromyalgia flare-ups can be debilitating.

Fibromyalgia patients are generally treated with pain-relieving medication customized to their symptoms. Many patients will begin with an OTC pain reliever like Tylenol and then progress to a prescription pain medication when symptoms require. Some patients respond to anti-seizure drugs.

Fibromyalgia can lead to anxiety or depression. Proactive mental health care helps. Traditional talk therapy is one way of addressing a sense of mourning or other negative feelings that arise from fibromyalgia. Therapy can talk place in a group setting or one-on-one.

Many people with fibromyalgia also experience sleep disturbances such as insomnia – making it harder to fall asleep or stay asleep. This may make them vulnerable to other health complications. Fibromyalgia treatment often includes a number of measures intended to raise sleep quality. Many states allow the use of medical cannabis for fibromyalgia.

What Research Currently Exists Around Fibromyalgia?

Fibromyalgia research has not yet discovered why some people develop the disorder. However, fibromyalgia clinical studies have been launched to understand the connection between this disorder and several others that often occur at the same time.

Some common co-morbid disorders include:

  • Irritable Bowel Syndrome (IBS)
  • Frequent headaches, including migraine
  • Tempromandibular joint disorders (TMJ)
  • Interstitial cystitis

Physicians believe that more effective fibromyalgia treatments may be possible if links between these disorders are studied in greater detail. Likewise, fibromyalgia clinical resources exploring genetic disease factors are still under development.

Why Are Further Fibromyalgia Clinical Trials Important?

The ultimate goal of fibromyalgia medical research is to understand the disease’s underlying causes and create fibromyalgia medication that can arrest or cure it. A fibromyalgia cure is still many years away, but it could improve quality of life for millions of Americans. At the same time, new fibromyalgia diagnosis tools could identify those in need of early treatment.

Current Fibromyalgia Clinical Trials

Fibromyalgia medical research is being actively performed throughout the U.S. and around the world. It is not unusual to see new fibromyalgia clinical trials every few months. This is the current list of fibromyalgia clinical trials archived at ClinicalTrials.gov. To add a fibromyalgia clinical trial to our site, simply contact our team.

  • Foot Plantar Pressure Changes After Plantar Dry Needling
    on November 13, 2020 at 5:00 pm

    Conditions:   Myofascial Pain Syndrome;   Foot DiseasesIntervention:   Other: Static footprintSponsor:   Mayuben Private ClinicRecruiting

  • Explosive Synchronization of Brain Network Activity in Chronic Pain
    on October 28, 2020 at 4:00 pm

    Conditions:   Fibromyalgia;   Healthy VolunteersInterventions:   Diagnostic Test: EEG;   Diagnostic Test: Neuroimaging EEG/fMRI;   Device: HD-tDCS treatments;   Device: Sham HD-tDCS treatmentsSponsors:   University of Michigan;   National Center for Complementary and Integrative Health (NCCIH)Recruiting

  • Efficacy of Electroacupuncture in Carpal Tunnel Syndrome
    on October 26, 2020 at 4:00 pm

    Conditions:   Carpal Tunnel;   Carpal Tunnel Syndrome;   Pain;   Pain Syndrome;   Pain Syndrome MyofascialIntervention:   Procedure: 8 sessions of electroacupuncture to the upper limb with carpal tunnel syndromeSponsors:   Aretaieion University Hospital;   University of West Attica;   Lilian Voudouri FoundationRecruiting

  • Treatment of Fibromyalgia and CFS With Ribose, Ashwagandha, Rhodiola, Licorice, Schisandra and Green Tea Extract
    on October 22, 2020 at 4:00 pm

    Conditions:   Fibromyalgia;   CFSIntervention:   Dietary Supplement: Smart Energy SystemSponsor:   Practitioners Alliance NetworkRecruiting

  • Treatment of CFS and Fibromyalgia With HRG 80 Red Ginseng
    on October 22, 2020 at 4:00 pm

    Conditions:   Fibromyalgia;   CFSIntervention:   Dietary Supplement: HRG 80 Red GinsengSponsor:   Practitioners Alliance NetworkRecruiting

  • New Educational Tool for FM
    on October 1, 2020 at 4:00 pm

    Condition:   FibromyalgiaInterventions:   Behavioral: PNE-explained group;   Behavioral: PNE-read group;   Behavioral: TAU groupSponsors:   Hospital Universitari Vall d'Hebron Research Institute;   University of South AustraliaRecruiting

  • Effectiveness of VIRTUAL FIBROWALK STUDY
    on October 1, 2020 at 4:00 pm

    Condition:   FibromyalgiaInterventions:   Behavioral: TAU + multicomponent treatment VIRTUAL FIBROWALK;   Behavioral: Treatment as Usual (TAU);   Behavioral: TAU + Physiotherapy part of VIRTUAL FIBROWALKSponsor:   Hospital Universitari Vall d'Hebron Research InstituteRecruiting

  • Expiratory Muscle Training in Stroke
    on September 30, 2020 at 4:00 pm

    Conditions:   Stroke;   Mastication Disorder;   Temporomandibular Disorders;   Dysphagia;   Stomatognathic DiseasesIntervention:   Other: Expiratory muscle trainingSponsor:   Abant Izzet Baysal UniversityRecruiting

  • Efficacy of Sana Treatment in Fibromyalgia
    on September 29, 2020 at 4:00 pm

    Condition:   FibromyalgiaIntervention:   Device: Sana Sham DeviceSponsors:   Sana Health;   Duke UniversityRecruiting

  • Spray Stretch Technique Versus Sustain Pressure for Trapezius Triggers
    on September 23, 2020 at 4:00 pm

    Conditions:   Trigger Point Pain, Myofascial;   Mechanical Neck PainInterventions:   Combination Product: Spray and Stretch technique (Ethyl chloride);   Other: Sustain pressure releaseSponsor:   Riphah International UniversityRecruiting

  • Effectiveness of Bowen Therapy for Pain Management in Patients With Fibromyalgia
    on September 18, 2020 at 4:00 pm

    Condition:   FibromyalgiaInterventions:   Other: Conventional;   Procedure: BowenSponsors:   Alice Ho Miu Ling Nethersole Hospital;   Chinese University of Hong KongRecruiting

  • High-definition Transcranial Electrical Stimulation for Fibromyalgia
    on September 16, 2020 at 4:00 pm

    Condition:   FibromyalgiaInterventions:   Device: HD-tCES;   Device: Sham HD-tCESSponsors:   Taipei Medical University;   Ministry of Health and WelfareRecruiting


About ten million people in the U.S. have fibromyalgia – as does 6% of the world population. Yet, the origin of fibromyalgia remains mysterious. Proactive treatment for fibromyalgia relies on today’s fibromyalgia clinical studies and those who choose to participate. Patients of any age and background, including those with a family history of fibromyalgia, have important roles to play.

Match to Fibromyalgia Clinical Trials

  • Access to cutting-edge treatments
  • Latest clinical trials
  • Find trials in your area