HomeClinical TrialsA Guide to Fibromyalgia and Clinical Trials
ibromyalgia is a common musculoskeletal condition. It causes pervasive muscle pain and tenderness that can appear alongside fatigue and cognitive or mood changes. Pain and spasms may occur virtually anywhere in the body.
The origins of fibromyalgia are not fully understood. Experts believe fibromyalgia amplifies painful sensations by changing how the brain processes them. Once it develops, fibromyalgia generally persists for life, although symptoms may change.
Anyone can develop fibromyalgia, although about 70%-90% of sufferers are women. It is often experienced in the wake of a physical trauma, surgery, infection, or substantial psychological stress. However, it does not always have a triggering event.
Mental health symptoms are commonly experienced alongside fibromyalgia pain. This includes characteristic “fibro fog” that makes it difficult to focus and pay attention. Many fibromyalgia patients also suffer anxiety and depression.
There is no cure for fibromyalgia. Fibromyalgia treatment focuses on managing symptoms and maintaining quality of life. Fibromyalgia symptoms do not necessarily worsen with age, but they tend to be pervasive. Fibromyalgia flare-ups can be debilitating.
Fibromyalgia patients are generally treated with pain-relieving medication customized to their symptoms. Many patients will begin with an OTC pain reliever like Tylenol and then progress to a prescription pain medication when symptoms require. Some patients respond to anti-seizure drugs.
Fibromyalgia can lead to anxiety or depression. Proactive mental health care helps. Traditional talk therapy is one way of addressing a sense of mourning or other negative feelings that arise from fibromyalgia. Therapy can talk place in a group setting or one-on-one.
Many people with fibromyalgia also experience sleep disturbances such as insomnia – making it harder to fall asleep or stay asleep. This may make them vulnerable to other health complications. Fibromyalgia treatment often includes a number of measures intended to raise sleep quality. Many states allow the use of medical cannabis for fibromyalgia.
Fibromyalgia research has not yet discovered why some people develop the disorder. However, fibromyalgia clinical studies have been launched to understand the connection between this disorder and several others that often occur at the same time.
Some common co-morbid disorders include:
Physicians believe that more effective fibromyalgia treatments may be possible if links between these disorders are studied in greater detail. Likewise, fibromyalgia clinical resources exploring genetic disease factors are still under development.
The ultimate goal of fibromyalgia medical research is to understand the disease’s underlying causes and create fibromyalgia medication that can arrest or cure it. A fibromyalgia cure is still many years away, but it could improve quality of life for millions of Americans. At the same time, new fibromyalgia diagnosis tools could identify those in need of early treatment.
Fibromyalgia medical research is being actively performed throughout the U.S. and around the world. It is not unusual to see new fibromyalgia clinical trials every few months. This is the current list of fibromyalgia clinical trials archived at ClinicalTrials.gov. To add a fibromyalgia clinical trial to our site, simply contact our team.
Conditions: Temporomandibular Disorder; Myofascial Pain; Cannabis; Electromyography; Occlusal Appliance; CBDInterventions: Drug: CBD occlusal appliance; Device: Acrylic resin occlusal applianceSponsor: Medical University of SilesiaRecruiting
Condition: Trigger Point Pain, MyofascialInterventions: Other: Positional release technique; Other: Traditional physical therapySponsor: Riphah International UniversityRecruiting
Condition: Trigger Point Pain, MyofascialInterventions: Drug: Magnesium sulfate; Drug: SalineSponsor: Fayoum UniversityRecruiting
Condition: Temporomandibular DisordersInterventions: Procedure: Dry needling and placebo injection; Procedure: Injection and placebo dry needling; Procedure: Dry needling and injection; Procedure: Placebo dry needling and placebo injectionSponsor: Josue Fernandez CarneroRecruiting
Conditions: Neck Pain, Posterior; Trapezius Muscle StrainInterventions: Other: Dry needling; Other: Sham needlingSponsor: University GhentRecruiting
Conditions: Myofascial Trigger Point Pain; Quadratus Lumborum Syndrome; Positional Fault of Pelvis; Myofascial Trigger Point in Quadratus LumborumInterventions: Other: Dry needling; Other: Dry cuppingSponsor: Riphah International UniversityRecruiting
Conditions: Myofascial Pain Syndromes; CancerIntervention: Combination Product: 1% lidocaine injection in trigger pointsSponsor: University of Sao PauloRecruiting
Conditions: Low Back Pain; Myofascial Pain Syndrome Lower BackInterventions: Drug: Treatment of Myofascial Pain Syndrome in the low back. This intervention will be based on outcomes of the medications listed below.; Drug: Evaluation of functional ability using a patient centered functional score known as the Modified Oswestry Disability Index (MODI). The intervention will be based on outcomes of medications below.; Drug: Following up with participants 60-72 hours after treatment in the Emergency Department. This intervention will be based on outcomes of the medications listed below.Sponsor: Madigan Army Medical CenterRecruiting
Conditions: Temporomandibular Disorders; Orofacial PainInterventions: Device: stabilization splint; Procedure: physical therapy; Device: placebo splintSponsor: Croatian Science FoundationRecruiting
Conditions: Fibromyalgia; Kinesiophobia; Cognitive DysfunctionIntervention: Sponsor: Bozyaka Training and Research HospitalRecruiting
Conditions: Dry Needling; Soreness, Muscle; Trigger Point Pain, MyofascialInterventions: Other: Concentric contraction exercise; Other: Isometric contraction exercise; Other: Eccentric contraction exercise; Other: Analytic passive stretchingSponsor: University of AlcalaRecruiting
Conditions: Fibromyalgia; Covid-19 Fear; Covid-19 Anxiety; Daily Life; Sleep Quality; Anxiety DepressionIntervention: Sponsor: Diskapi Yildirim Beyazit Education and Research HospitalRecruiting
About ten million people in the U.S. have fibromyalgia – as does 6% of the world population. Yet, the origin of fibromyalgia remains mysterious. Proactive treatment for fibromyalgia relies on today’s fibromyalgia clinical studies and those who choose to participate. Patients of any age and background, including those with a family history of fibromyalgia, have important roles to play.