A Guide To Weight Loss

Match to Weight Loss Clinical Trials

Weight Loss and Your Health

Recent research indicates about 70 million U.S. adults are obese and 99 million are overweight. In 2017, 42% of Americans were obese, a rise of around 12% compared to 1999.

All in all, experts agree obesity is a widespread problem in the United States. The average person seems to concur: About 45 million Americans go on a diet each year.

Unfortunately, standard diet and exercise regimes produce limited results for many people. In recent years, the emergence of serious health complications related to weight has led to more people seeking medical supervision for their weight loss efforts.

The foods that we eat are the foundation of a good health. Food does not only provide us with the essential nutrients, vitamins, and minerals that our bodies need to function; a good diet is key for preventing chronic conditions such as heart disease and diabetes, both of which are among the top leading causes of death in the United States.

When we think of food and nutrition in relation to our health, we tend to only think about obesity. In many countries, including the United States, obesity is an epidemic and is one of the main culprits of premature and preventable deaths.

But obesity is not the only consequence of a bad diet; too many or too little of particular nutrients can also be very detrimental to your health. Contrary to obesity, which is often caused by poor diet choices and excessive eating, eating too little or not eating the adequate amount of nutrients can cause malnutrition, or nutritional deficiencies. A nutritional deficiency means that your body is not receiving the nutrients it needs to function properly.

On the whole, people who maintain a healthy weight, exercise regularly, and eat a balanced diet have a higher life expectancy than those who are classified as overweight or obese.

What Conditions Are Associated With Weight Loss?

As weight increases, so too does the risk of many different health conditions. High blood pressure is a common complication of being overweight that can also raise one’s risk of heart attack and stroke. Overweight people are also less likely to survive these events.

Unhealthy weight raises the risk of many other conditions, including heart disease, diabetes, high cholesterol, arthritis, and several others. Many of these are common. Overweight people who already have a genetic disposition to any of these conditions are at very high risk.

Sustained weight loss and management can curb many of these risks. If weight loss is achieved before health problems begin, the patient becomes less likely to develop those complications, even with advancing age. Health benefits are brought about by increased heart efficiency, improved muscle mass, better blood circulation, and many other factors.

Match to Weight Loss Clinical Trials

Weight Loss Methods and Lifestyle Changes

Weight loss methods range from self-directed diet and exercise to medically supervised weight loss regimes to surgical intervention. Many patients benefit from combining several methods.

Besides from giving you all the nutrients you need, a good diet is one of the best preventive strategies to avoid heart disease, which is the leading cause of death in the world. Keeping your portions under control, eating the recommended amount of fruits and vegetables, and limiting the consumption of sugars and unhealthy fats has been proven to be the best methods for keeping your heart healthy and strong and a balanced weight.

Weight loss surgery, such as lap band surgery, is generally only practiced on those who are severely obese whose condition has not responded to a medically supervised weight loss plan.

Lifestyle changes focus on reducing portions, changing meal times, improving nutrition, and raising the amount of physical exercise a person engages in. Once weight loss is achieved, these lifestyle changes must remain in place to avoid regaining lost weight in the future.

Recent Weight Loss Medical Research

Weight loss is one of human biology’s most complex topics. Weight loss medical research can focus on many aspects of this challenging process.

Some researchers are interested in the way the body signals appetite and stores fat and how these functions can be adjusted in healthy ways. Others focus on the neurology of behaviors that can lead to obesity or the role of hormones in the body’s weight regulation.

Why Are Further Weight Loss Clinical Trials Necessary?

Over the last several years, a great deal of weight loss medical research has focused on metabolic syndrome, a cluster of conditions associated with weight gain. Weight loss clinical trials are essential to understanding how this syndrome impedes weight loss for teens, adolescents, and adults, and the role played by co-occuring conditions.

While the first thing that comes to mind when we talk about clinical trials are drugs and medical devices, clinical trials are also performed to test new methods for screening and diagnosing conditions, and well as to test the effectiveness of health promoting interventions for specific conditions.

Clinical trials in diet and nutrition are extremely important to understanding how and why the nutrients that we eat play a role in our health. Learning how food can serve as a tool for not only preventing but also help treating many conditions can potentially save the lives of many.

Just like any other clinical trial, a food and nutrition trial is a clinical research study that has been designed by medical experts who have found a potentially beneficial therapy, intervention, or drug that needs to be tested.

Clinical trials follow very strict protocols that have to be approved by the FDA, internal review boards, and any other agencies designated to oversee that the trial is being conducted in an ethical and safe manner.

Current Weight Loss Clinical Trials for 2023

Though clinical trials are conducted by experts and always regulated by agencies that ensure the safety of all participants, you should always know that there is an inherent risk in participating in any kind of research study.

Clinical trials associated with diet, nutrition, or weight loss may involve anything from taking a medication to eating a certain diet, so it is important to understand what are the components of the study and if you are willing and capable to do it before you make the commitment.

However, clinical trials are always voluntary, so you are free to withdraw your participation at any point in time without any consequences. When you agree to participate in a clinical trial you will sign an informed consent document stating that you understand and agree to participate in the study. But that doesn’t mean that you have to stay if until the end of the study should you decide you no longer want to be a part of it.

This directory of weight loss clinical trials includes all weight loss clinical studies in the ClinicalTrials.gov database. To add a study to our list, contact us.


Virtually all Americans are affected by the health issues caused by weight or know someone who is. However, sustained weight loss is not simply a matter of “willpower.” More weight loss clinical trials are needed to uncover the complex biological processes that can make weight loss difficult.

Match to Weight Loss Clinical Trials