E

yes are sensitive organs, so it doesn’t come as a surprise that most people will have some kind of vision-related problem at some point in their lives. Eye problems can be mild and short-lived, like pink eye, allergies, mild infections, etc. However, diseases such as glaucoma, macular degeneration, ocular melanoma, and many others can be very dangerous.

Aside from eye diseases, many people have to wear eyeglasses because they have trouble seeing up close or identifying objects that are far away. This problem is called refractive error, and it happens when the shape of the eye prevents light from accurately entering into the retina.

Most types of refractive errors can occur at any age, and in many people their risk of developing refractive errors significantly increase if their parents also had them. While there are many treatments available for both eye diseases and refractive errors, there is still much to learn about eye health and how to prevent common vision-related problems.

Match to Ophthalmology Clinical Trials

  • Access to cutting-edge treatments
  • Latest clinical trials
  • Find trials in your area

What Are Clinical Trials?

Clinical trials are research studies designed to test, observe, and evaluate the safety and effectiveness of a new medical treatment or intervention. This intervention can have many forms; in some cases the intervention is a new medication designed to treat or prevent the occurrence of a disease, it can be a new surgical procedure or technique, or a behavior modification intervention of lifestyle changes.

After researchers design a study and conduct preliminary tests, they invite volunteers to take part in the clinical trial part of the study to test the intervention. Volunteers can be found in many places; some people might hear about a research study from their doctor, particularly if they have a condition or disease that is being studied. Some bigger research studies are even broadcasted on the radio or television to recruit participants.

The most important thing you should know about clinical trials is that they are always completely voluntary. The decision to participate or not is entirely up to you, and if you decide not to participate or to withdraw from a study, you are still entitled to the same healthcare you were receiving before.

Why Are Ophthalmological Clinical Trials Important?

Our eyes are one of the most important organs in our bodies; without healthy eyes we would not be able to see the world around us. However, there are many conditions that can put a damper into good vision.

During clinical trials, researchers are not only testing medications or devices to figure out if they are effective or not, they are also learning how certain diseases and conditions develop and act in the body to draw conclusions about how to prevent them.

Degenerative conditions of the eye often end up in total or partial blindness, which can rarely be reversed. Ophthalmological clinical trials provide doctors and scientist with a lot of information about these conditions, so that they can keep developing treatments and preventive strategies to avoid irreparable ocular damage.


Are Clinical Trials Safe?

Clinical trials are generally safe. Before a researcher or doctor even begins recruiting participants for their study, they must develop a very thorough plan explaining the reason for the study and how they are planning to conduct it. This is called a study protocol. The study protocol must be approved by internal and external regulatory agencies that will determine if their study is safe, fair, and that it will not put any participant in risk.

All these measures are taken to ensure that even if complications or side effects come up during the study, all research staff is prepared to handle them and even terminate the study if necessary.

What Will I Gain From A Clinical Trial?

Some clinical trials offer monetary compensations for participants. However, by participating in a clinical study, you will be helping the medical field advance their knowledge about a particular condition or disease. By doing this, and even if the intervention you participated in did not give you any direct benefits, you will be helping pave the wave for more effective and potentially life-saving interventions in the future.

ClinicalTrials.gov: Recruiting Studies | Ophthalmopathy | Last update posted in the last 300 days Studies found on ClinicalTrials.gov by a search of: Recruiting Studies | Ophthalmopathy | Last update posted in the last 300 days

  • Eye Length Signal With Myopia Control
    on March 24, 2021 at 4:00 pm

    Condition:   MyopiaIntervention:   Device: SpectaclesSponsor:   Brien Holden Vision InstituteRecruiting

  • Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery Including a Corneal Endothelial Cell Sub-study
    on March 23, 2021 at 4:00 pm

    Condition:   Ocular Inflammation and Pain After Cataract SurgeryInterventions:   Drug: APP13007, 0.05%;   Drug: Matching Vehicle Placebo for APP13007, 0.05%Sponsor:   Formosa Pharmaceuticals, Inc.Recruiting

  • Assessment of Accommodation Behavior in Children Under Myopia Control Treatment (Pilot Study)
    on March 19, 2021 at 4:00 pm

    Conditions:   Accomodation;   Biofeedback Training;   MyopiaIntervention:   Device: Multifocal soft contact lens wear for myopia controlSponsors:   State University of New York College of Optometry;   University Hospital TuebingenRecruiting

  • CDSS of Traditional Chinese Medicine Intervention for Dry Eye Syndrome
    on March 19, 2021 at 4:00 pm

    Condition:   Dry Eye SyndromesInterventions:   Behavioral: Clinical Decision Support System;   Other: Routine interventionSponsor:   Peking University Third HospitalRecruiting

  • APIOC Sphere and APIOC Astigmatism
    on March 19, 2021 at 4:00 pm

    Conditions:   Myopia;   Hyperopia;   AstigmatismIntervention:   Device: APIOC Sphere and APIOC AstigmatismSponsor:   Lentechs, LLCRecruiting

  • Natural History Study of Retinitis Pigmentosa Type 11
    on March 18, 2021 at 4:00 pm

    Conditions:   Retinitis Pigmentosa 11;   Retinitis PigmentosaIntervention:   Diagnostic Test: Clinical examinationsSponsor:   Oslo University HospitalRecruiting

  • Intraoperative Analysis of the Central Retina in ERF
    on March 17, 2021 at 4:00 pm

    Conditions:   Epiretinal Membrane;   Macular PuckerIntervention:   Procedure: Intraoperative ERM and ILM staining with their assessment and removalSponsors:   The S.N. Fyodorov Eye Microsurgery State Institution;   Makarenko Irina Romanovna;   Zgoba Mariana IgorevnaRecruiting

  • Fatigue in Primary Sjögren's Syndrome
    on March 17, 2021 at 4:00 pm

    Conditions:   Sjogren's Syndrome;   Fatigue;   Pain Syndrome;   Depression;   Anxiety;   FibromyalgiaInterventions:   Diagnostic Test: FACT-F questionnaire;   Diagnostic Test: Beck Depression Inventory;   Diagnostic Test: Beck Anxiety Inventory;   Diagnostic Test: Insomnia severity index.;   Other: ESSPRI;   Other: ESSDAI;   Other: Pain Detect QuestionnaireSponsor:   Bursa Yüksek İhtisas Education and Research HospitalRecruiting

  • Increasing Vision Center Service Utilization
    on March 16, 2021 at 4:00 pm

    Condition:   Eye DiseasesIntervention:   Other: Intervention ArmSponsors:   Seva Foundation;   Dr Shroff's Charity Eye Hospital;   Indian Institute of Public Health, India;   Seva Canada;   Queen's University, BelfastRecruiting

  • Intravitreal Bevacizumab vs Laser vs Combination of Bevacizumab and Modified Laser in PDR
    on March 16, 2021 at 4:00 pm

    Condition:   Proliferative Diabetic RetinopathyInterventions:   Drug: receive 4 monthly IVB injections and then rescue IVB;   Drug: PRP group;   Drug: IVB injections and a modified laserSponsor:   Shahid Beheshti University of Medical SciencesRecruiting

  • Topotecan and Melphalan for Retinoblastoma
    on March 16, 2021 at 4:00 pm

    Conditions:   Retinoblastoma;   Chemotherapy EffectInterventions:   Drug: Topotecan;   Drug: MelphalanSponsor:   Sun Yat-sen UniversityRecruiting

  • SS-INQ Information Needs Questionnaire in Sjögren's Syndrome
    on March 15, 2021 at 4:00 pm

    Condition:   Sjögren's SyndromeIntervention:   Other: Phase 1 Observational InterviewsSponsor:   University College, LondonRecruiting

Match to Ophthalmology Clinical Trials

  • Access to cutting-edge treatments
  • Latest clinical trials
  • Find trials in your area
Sources
  1. Clinical Trials in Vision Research. Sourced from: https://nei.nih.gov/health/clinicaltrials_facts
  2. Common Eye Symptoms. Sourced from: https://www.aoa.org/patients-and-public