The most common acne symptoms include:
What is Acne?
A
cne is a common condition characterized by skin lesions that are caused when hair follicles get plugged with oil and dead skin cells. Acne is most common in teenagers because the skin’s oil content changes in the teen years. However, it can affect people of any age and appear throughout the human body.
Match to Acne Clinical Trials
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Acne Symptoms and Associated Conditions
- Whiteheads: Plugged skin pores that are closed
- Blackheads: Plugged skin pores that are open
- Papules: Sensitive red bumps
- Pimples: Papules gathering pus at the tips
- Nodules: Solid, painful lumps under the skin
- Cystic lesions: Painful, pus-filled lumps under skin
Of these, nodules and cystic lesions are relatively rare. Many teens will experience periodic acne episodes (breakouts) consisting of whiteheads, blackheads, and pimples. Hormonal changes and other factors influence the timing of these breakouts, which tend to taper off after the teen years.
For some acne patients, the condition can be persistent. It may last into the 20s or periodically recur throughout life. The longer someone has untreated acne, the more likely they are to have scarring and other more severe complications. Acne can detract significantly from mental health and self-image.
Acne in women over 25 is more common than acne in men of the same age. Flare-ups can be brought on by hormonal changes and are not usually cause for alarm. However, a sudden episode of acne in an adult with no recent history of it may suggest an underlying heath disorder, such as an allergic reaction.
Acne Medication and Treatments
Acne treatments are widely available over the counter. Most cases of acne will clear up without the need for a prescription acne medication. Common acne treatments focus on removing oil and irritants from the upper layer of the skin to make it less likely that hair follicles will become clogged.
Persistent acne for three months or more with no visible improvement after over the counter treatment may require a doctor’s help. Dermatologists, who study conditions of the skin, are usually consulted. A dermatologist may recommend powerful acne medication in the form of a prescription cream.
Acne can become painful and lead to scarring if a breakout is attended by severe inflammation or by bacterial infection. A dermatologist can prescribe acne medication that will help with these symptoms or refer the patient to a doctor who can.
Acne Recovery and Lifestyle Changes
The most severe cases of acne may require several months or even years to treat. However, most patients will eventually overcome acne without the need for many, if any, significant lifestyle changes. Contrary to popular belief, neither dirty skin nor oily foods contribute to acne. However, patients who wear makeup may be advised to switch to an oil-free brand. Likewise, patients should be alert to future breakouts and see a doctor if needed.
Current Acne Clinical Trials
Current acne clinical research focuses on new acne treatments for acne patients suffering from the most intense and prolonged cases, a small fraction of patients overall. This list includes all current acne clinical trials registered with ClinicalTrials.gov. To tell us about a new acne clinical trial, contact us today.
- Combined Low-Dose Isotretenion and Long-Pulsed 1064 ND-YAG Laser in the Treatment of Acne Erythemaon November 18, 2022 at 5:00 pm
Condition: Acne VulgarisIntervention: Combination Product: Combined Low-Dose Isotretenion and Long-Pulsed 1064 ND-YAG LaserSponsor: Zagazig UniversityRecruiting
- Duobrii Treatment of Acne Keloidalis Nuchae (AKN)on November 8, 2022 at 5:00 pm
Conditions: Acne Keloidalis Nuchae; AKNInterventions: Drug: Duobrii; Drug: Placebo; Drug: BryhaliSponsors: Icahn School of Medicine at Mount Sinai; Bausch Health Americas, Inc.Recruiting
- The MIRIA Acne Scar Studyon October 28, 2022 at 4:00 pm
Condition: Acne Scars - Mixed Atrophic and HypertrophicIntervention: Device: MIRIA LaserSponsor: AVAVA, Inc.Recruiting
- Study Comparing Trifarotene Cream, 0.005% To AKLIEF ® (Trifarotene 0.005% Cream) In The Treatment Of Acne Vulgarison September 22, 2022 at 4:00 pm
Condition: Acne VulgarisInterventions: Drug: Trifarotene 0.005 % Topical Cream; Drug: AKLIEF®; Drug: PlaceboSponsors: Teva Pharmaceuticals USA; Teva Pharmaceuticals, Inc.Recruiting
- Effectivity and Safety of Combination Cream of Salicylic Acid, Aqua Posae Filiformis, Niacinamide, Lipohydroxy Acid, Procerad and Zinc PCAon August 11, 2022 at 4:00 pm
Condition: Acne VulgarisInterventions: Drug: Combination Cream; Drug: Adapalene 0,1% creamSponsor: Dr.dr.Irma Bernadette, SpKK (K)Recruiting
- Investigation of the Tolerability of Two Facial Cleansing Routines for Mild to Moderate Acneon July 6, 2022 at 4:00 pm
Condition: AcneInterventions: Combination Product: Geologie Acne Regimen - one side of face; Combination Product: Proactive Acne Regimen - other side of faceSponsor: Northwestern UniversityRecruiting
- A Study of a Laser for the Treatment of Acne Vulgarison June 24, 2022 at 4:00 pm
Condition: Acne VulgarisInterventions: Device: 1726nm Laser System; Device: Sham Laser SystemSponsors: Cutera Inc.; ethica Clinical Research Inc.Recruiting
- Study in Subjects to Evaluate the Safety, Tolerability and Pharmacokinetics of GT20029on June 23, 2022 at 4:00 pm
Conditions: Acne Vulgaris; Androgenetic AlopeciaInterventions: Drug: GT20029 Gel; Drug: GT20029 Gel PlaceboSponsor: Suzhou Kintor Pharmaceutical Inc,Recruiting
- Impact of COVID-19 Vaccination on Serum 25-hydroxyvitamin D Levelon June 1, 2022 at 4:00 pm
Conditions: Acne Vulgaris; Vitamin D Deficiency; COVID-19Intervention: Diagnostic Test: Blood test and skin evaluationSponsor: National Taiwan University HospitalRecruiting
- LiftActiv B3 in Post Inflammatory Hyperpigmentation (PIHP)on April 14, 2022 at 4:00 pm
Conditions: Acne; Post Inflammatory HyperpigmentationInterventions: Drug: Liftactiv B3; Other: SunscreenSponsors: University of Miami; Vichy LaboratoiresRecruiting
- Evaluation of Sonelokimab for the Treatment of Patients With Active Moderate to Severe Hidradenitis Suppurativaon April 11, 2022 at 4:00 pm
Condition: Hidradenitis SuppurativaInterventions: Drug: Sonelokimab (M1095); Drug: Adalimumab; Other: PlaceboSponsor: MoonLake Immunotherapeutics AGRecruiting
- Almond Supplementation on Mild to Moderate Acneon March 8, 2022 at 5:00 pm
Condition: Acne VulgarisInterventions: Other: Food: whole almonds; Other: Food: non-nut snackSponsors: Integrative Skin Science and Research; Almond Board of CaliforniaRecruiting
Conclusion
Virtually everyone will experience acne at some point in life. When acne lingers, however, it should be treated as a serious skin condition. Acne clinical trials offer the opportunity to help prevent and treat long-term acne. Acne clinical research is continuing to uncover important information on hormonal health and other factors. Acne may never disappear for good, but better acne treatments and acne medications are on the horizon.
Match to Acne Clinical Trials
- Access to cutting-edge treatments
- Latest clinical trials
- Find trials in your area