California is currently home to 5605 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Regional Blocks for Lateral Condyle Fractures
Recruiting
The purpose of this study is to investigate the post-operative pain control in pediatric patients with closed lateral condyle fractures who undergo open reduction and percutaneous pinning. Patients will be randomized into one of two groups. Group 1 will receive an infraclavicular nerve block to the affected extremity by a fellowship trained pediatric anesthesiologist prior to surgery. Group 2 will undergo the Orthopaedic Institute of Children's (OIC) standard preoperative protocol. Post-operativ... Read More
Gender:
ALL
Ages:
Between 4 years and 12 years
Trial Updated:
03/26/2025
Locations: Orthopaedic Institute for Children, Los Angeles, California
Conditions: Fractures, Closed, Humeral Fractures, Pain
Supracondylar Post-Operative Pain Study
Recruiting
The purpose of this study to investigate post-operative pain control in pediatric patients with closed supracondylar humerus fracture who undergo closed reduction and percutaneous pinning. Currently, it is standard of care that patients receive a narcotic prescription for post-operative pain control. All patients will initially be seen in our pediatric urgent care and recruited at the time of surgery. Patients will be randomized to receiving acetaminophen and ibuprofen or acetaminophen and oxyco... Read More
Gender:
ALL
Ages:
Between 5 years and 12 years
Trial Updated:
03/26/2025
Locations: Orthopaedic Institute for Children, Los Angeles, California
Conditions: Supracondylar Humerus Fracture
TAP Blocks With Ropivacaine Continuous Infusion Catheters vs Single Dose Liposomal Bupivicaine After Kidney Transplant
Recruiting
This study is a comparison of the analgesic efficacy of transversus abdominis plane (TAP) blocks with ropivacaine bolus plus continuous ropivacaine infusion via catheters versus single shot TAP blocks with liposomal bupivacaine.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: University of California Davis, Sacramento, California
Conditions: Transplant;Failure,Kidney, Pain, Postoperative
Effects of Fresh Watermelon Consumption on Satiety and Cardiometabolic Health
Recruiting
The goal of the proposed study is to determine the effects of fresh watermelon fruit consumption on satiety, metabolic parameters and weight management.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/26/2025
Locations: Exercise and Nutritional Sciences, SDSU, San Diego, California
Conditions: Satiety
Effects of Watermelon Juice on Heart Rate Recovery and Post-exercise Muscle Soreness
Recruiting
The purpose of this study was to determine the effects of a pre-exercise, single practical dose of watermelon juice, Gatorade, sugar water or water on heart rate recovery, blood lactate levels, and 24-hour post exercise muscle soreness.
Gender:
ALL
Ages:
Between 21 years and 50 years
Trial Updated:
03/26/2025
Locations: Exercise and Nutritional Sciences, SDSU, San Diego, California
Conditions: Heart Rate Recovery
Effects of Mixed Nut Consumption on Satiety and Weight Management
Recruiting
The first goal of the proposed study is to determine acute and long-term effects of mixed nuts (almonds, hazelnuts, pecans, pistachios, walnuts, and peanuts) on metabolic parameters and weight management. While numerous studies have shown the beneficial effects of nuts on promoting negative energy balance and weight loss, mechanistic studies exploring how the inclusion of nuts in the diet promotes a negative energy balance and weight loss have not been conducted. The second goal is to determine... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/26/2025
Locations: School of Exercise and Nutritional Sciences, SDSU, San Diego, California
Conditions: Satiety
Bio-Repository of High Risk Cohorts for the Early Detection of Pancreas Cancer
Recruiting
Bio-repository to collect bio-specimens from patients with 1) pancreatic cysts and 2) patients at high risk, defined by family history and/or genetic mutations, for pancreatic cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: Stanford University, Stanford, California
Conditions: Pancreatic Cyst, Pancreas Disease
Microbiome Sampling During Endurance Exercise
Recruiting
The small intestine and feces of subjects undergoing endurance exercise will be sampled to examine their microbiome composition
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/25/2025
Locations: Stanford University, Stanford, California
Conditions: Healthy, Exercise-Induced Lactic Acidemia
Evaluation of D-Fi for the Treatment of Wounds Due to DEB
Recruiting
The purpose of this study is to determine whether administration of D-Fi in addition to standard of care improves wound healing as compared to standard of care alone (control) in children, adolescents, and adults with Dystrophic Epidermolysis Bullosa.
Gender:
ALL
Ages:
2 years and above
Trial Updated:
03/25/2025
Locations: Stanford University School of Medicine, Dermatology, Redwood City, California
Conditions: Dystrophic Epidermolysis Bullosa
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular Degeneration
Recruiting
This is a multi-center, randomized, double-masked, active-comparator-controlled, Phase 3 study in a broad participant population (treatment-naïve and treatment-experienced) with neovascular (wet) age-related macular degeneration (nAMD). The study will evaluate a single intravitreal (IVT) injection of Ixo-vec compared to an active comparator. The primary endpoint of this study is the mean change in best corrected visual acuity (BCVA) of Ixo-vec compared to an active comparator measured at an aver... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
03/25/2025
Locations: Adverum Clinical Site 169, Fullerton, California
Conditions: Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD
A Study of Navenibart in Participants with Hereditary Angioedema
Recruiting
This is a Phase 3 multicenter, randomized, double-blind, placebo-controlled clinical trial evaluating the safety and efficacy of subcutaneous administration of navenibart in adult and adolescent participants with type 1 or type 2 hereditary angioedema (HAE). The goal of this clinical trial is to evaluate the efficacy and safety of navenibart compared to placebo in preventing HAE attacks in participants with HAE.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
03/25/2025
Locations: Raffi Tachdjian MD, Inc, Santa Monica, California
Conditions: Hereditary Angioedema (HAE)
Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult Patients With Moderate to Severe Hidradenitis Suppurativa
Recruiting
The purpose of this study is to establish the efficacy, safety, and tolerability of remibrutinib (LOU064) Dose A and Dose B compared to placebo in participants with moderate to severe hidradenitis suppurativa (HS).
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
03/25/2025
Locations: Ctr for Dermatology Clinical Res, Fremont, California
Conditions: Hidradenitis Suppurativa