California is currently home to 5602 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
RCT for Latina Mental Health Using Web-Based Apps
Recruiting
This study compares a choice-driven, interactive, evidence-informed storytelling web-based app intervention with links to resources and treatment (Tx) recommendations (made by a character via her blog) and Tx locator, to a web-based app with links to publicly available informational internet videos, MH resources, and a treatment locator for at least moderately anxious/depressed untreated English and Spanish speaking Latinas to determine if a story-based, character-driven approach is more effecti... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/12/2025
Locations: UCLA, Los Angeles, California
Conditions: Mental Health, Anxiety, Depression, Well-Being, Psychological
Green Tea and Quercetin in Combination With Docetaxel Chemotherapy in Castration-resistant Prostate Cancer Patients
Recruiting
The goal of this clinical trial is to find out if taking natural products green tea and quercetin along with docetaxel chemotherapy improves the therapy of advanced prostate cancer, i.e., metastatic castration-resistant prostate cancer (mCRPC). It will also learn about the safety of this combination. Researchers will compare green tea plus quercetin to a placebo (a look-alike substance that contains no drug) in combination with docetaxel to see if green tea and quercetin works to improve the th... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
07/12/2025
Locations: Charles R. Drew University of Medicine and Science, Los Angeles, California
Conditions: Metastatic Castration-resistant Prostate Cancer (mCRPC)
QUELIMMUNE (SCD-PED) PediAtric SurVeillance REgistry
Recruiting
QUELIMMUNE is FDA-approved under an HDE for the treatment of pediatric patients (weight ≥10kg and age ≤22 years) with AKI due to sepsis or a septic condition on antibiotic therapy and requiring RRT. The purpose of this surveillance registry is to prospectively collect safety data among all patients treated with QUELIMMUNE under the HDE. More specifically, we intend on comparing the incidence of new (secondary) blood stream infections in the first 28 days after SCD-PED initiation to a comparator... Read More
Gender:
ALL
Ages:
22 years and below
Trial Updated:
07/12/2025
Locations: Lucile Packard Children's Hospital Stanford, Palo Alto, California
Conditions: Acute Kidney Injury, Acute Kidney Injury Due to Sepsis
Personalized Accelerated ChEmoRadiation (PACER) for Lung Cancer
Recruiting
The purpose of this study is to examine the use of hypofractionated accelerated radiation therapy (HART) to treat locally advanced lung cancer. Depending on the location and size of the tumor.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2025
Locations: Stanford University, Palo Alto, California
Conditions: Lung Cancer
Roadmap to Parenthood: Testing the Efficacy of a Decision Aid and Planning Tool for Family Building After Cancer
Recruiting
This study will test a decision support intervention that consists of a web-based 'decision aid and planning tool' for family building after cancer in a randomized controlled trial.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
07/12/2025
Locations: Stanford Universtiy, Palo Alto, California
Conditions: Quality of Life, Parenthood Status
Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness
Recruiting
This phase I/II trial studies the side effects and best dose of temozolomide and M1774 and how well they works in treating patients with cancer that has spread from where it first started (primary site) to other places in the body (metastatic) and may have spread to nearby tissue, lymph nodes, or distant parts of the body (advanced). Temozolomide is in a class of medications called alkylating agents. It works by damaging the cell's deoxyribonucleic acid (DNA) and may kill tumor cells and slow do... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2025
Locations: UC San Diego Moores Cancer Center, La Jolla, California
Conditions: Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Advanced Microsatellite Stable Colorectal Carcinoma, Metastatic Microsatellite Stable Colorectal Carcinoma, Stage III Colorectal Cancer AJCC v8, Stage IV Colorectal Cancer AJCC v8, Hematopoietic and Lymphatic System Neoplasm
GOLD: Brief Intervention to Reduce Anxiety and Promote Resilience in Families of Youth With Cancer
Recruiting
The purpose of this study is to examine a psychotherapeutic and psycho-educational intervention offered in virtual settings to caregivers of youth with cancer. Human subjects must be used because they are the object of the intervention.
Gender:
ALL
Ages:
Between 8 years and 18 years
Trial Updated:
07/12/2025
Locations: Stanford Cancer Institute, San Francisco, California
Conditions: Cancer
Study to Evaluate Percussive Ventilation Breathhold to Improve Lung Stereotactic Ablative Radiotherapy
Recruiting
The purpose of this research is to evaluate and determine the rate of successful administration of Percussive ventilation breathhold (PVB) to allow for more accurate radiotherapy for lung tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2025
Locations: Stanford Cancer Institute, Palo Alto, California
Conditions: Lung Cancer
Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery
Recruiting
The phase I/II trial studies the side effects and best dose of panitumumab-IRDye800 in diagnosing participants with malignant glioma who undergo surgery. Panitumumab-IRDye800 can attach to tumor cells and make them more visible using a special camera during surgery, which may help surgeons better distinguish tumor cells from normal brain tissue and identify small tumors that cannot be seen using current imaging methods.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2025
Locations: Stanford University School of Medicine, Palo Alto, California
Conditions: Malignant Brain Neoplasm, Malignant Glioma
A Study of HBS-201 (Pitolisant Delayed-release)
Recruiting
The purpose of this study is to assess the tolerability of HBS-201 when starting at a therapeutic dose in adult participants with narcolepsy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2025
Locations: Harmony Site 9, San Ramon, California
Conditions: Narcolepsy
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain
Recruiting
The main purpose of this study is to evaluate the efficacy and safety of retatrutide in relieving chronic low back pain in participants who have obesity or overweight. Participation in the study will last about 80 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2025
Locations: Ark Clinical Research - Fountain Valley, Fountain Valley, California
Conditions: Obesity, Overweight, Chronic Low Back Pain (CLBP)
A Randomized, Double Blind, Placebo Controlled, Clinical Study to Examine the Benefits of an Oral Product in Panelists With Menopausal Symptoms Including Vasomotor Symptoms (VMS).
Recruiting
Randomized, Double-Blind, Placebo-Controlled, Single-Center Clinical Study with a Run-in Baseline, Daily Diary Log, and Validated Questionnaires (Greene GCS) with Oral Dietary Supplement
Gender:
FEMALE
Ages:
Between 40 years and 65 years
Trial Updated:
07/11/2025
Locations: San Francisco Research Institute, San Francisco, California
Conditions: Healthy