California is currently home to 5590 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Supracondylar Post-Operative Pain Study
Recruiting
The purpose of this study to investigate post-operative pain control in pediatric patients with closed supracondylar humerus fracture who undergo closed reduction and percutaneous pinning. Currently, it is standard of care that patients receive a narcotic prescription for post-operative pain control. All patients will initially be seen in our pediatric urgent care and recruited at the time of surgery. Patients will be randomized to receiving acetaminophen and ibuprofen or acetaminophen and oxyco... Read More
Gender:
ALL
Ages:
Between 5 years and 12 years
Trial Updated:
03/26/2025
Locations: Orthopaedic Institute for Children, Los Angeles, California
Conditions: Supracondylar Humerus Fracture
TAP Blocks With Ropivacaine Continuous Infusion Catheters vs Single Dose Liposomal Bupivicaine After Kidney Transplant
Recruiting
This study is a comparison of the analgesic efficacy of transversus abdominis plane (TAP) blocks with ropivacaine bolus plus continuous ropivacaine infusion via catheters versus single shot TAP blocks with liposomal bupivacaine.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: University of California Davis, Sacramento, California
Conditions: Transplant;Failure,Kidney, Pain, Postoperative
Effects of Fresh Watermelon Consumption on Satiety and Cardiometabolic Health
Recruiting
The goal of the proposed study is to determine the effects of fresh watermelon fruit consumption on satiety, metabolic parameters and weight management.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/26/2025
Locations: Exercise and Nutritional Sciences, SDSU, San Diego, California
Conditions: Satiety
Effects of Watermelon Juice on Heart Rate Recovery and Post-exercise Muscle Soreness
Recruiting
The purpose of this study was to determine the effects of a pre-exercise, single practical dose of watermelon juice, Gatorade, sugar water or water on heart rate recovery, blood lactate levels, and 24-hour post exercise muscle soreness.
Gender:
ALL
Ages:
Between 21 years and 50 years
Trial Updated:
03/26/2025
Locations: Exercise and Nutritional Sciences, SDSU, San Diego, California
Conditions: Heart Rate Recovery
Effects of Mixed Nut Consumption on Satiety and Weight Management
Recruiting
The first goal of the proposed study is to determine acute and long-term effects of mixed nuts (almonds, hazelnuts, pecans, pistachios, walnuts, and peanuts) on metabolic parameters and weight management. While numerous studies have shown the beneficial effects of nuts on promoting negative energy balance and weight loss, mechanistic studies exploring how the inclusion of nuts in the diet promotes a negative energy balance and weight loss have not been conducted. The second goal is to determine... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/26/2025
Locations: School of Exercise and Nutritional Sciences, SDSU, San Diego, California
Conditions: Satiety
Bio-Repository of High Risk Cohorts for the Early Detection of Pancreas Cancer
Recruiting
Bio-repository to collect bio-specimens from patients with 1) pancreatic cysts and 2) patients at high risk, defined by family history and/or genetic mutations, for pancreatic cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: Stanford University, Stanford, California
Conditions: Pancreatic Cyst, Pancreas Disease
Microbiome Sampling During Endurance Exercise
Recruiting
The small intestine and feces of subjects undergoing endurance exercise will be sampled to examine their microbiome composition
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/25/2025
Locations: Stanford University, Stanford, California
Conditions: Healthy, Exercise-Induced Lactic Acidemia
Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)
Recruiting
This is a two-site randomized clinical trial aiming to test whether a modified investigational bariatric surgical procedure can improve gastroesophageal reflux disease (GERD) after sleeve gastrectomy.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
03/25/2025
Locations: University of California, Irvine, Orange, California
Conditions: Obesity, Bariatric Surgery, Sleeve Gastrectomy, Gastroesophageal Reflux Disease
BSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS
Recruiting
The goal of this clinical trial is to test BSB-1001 which is a new type of cellular therapy to treat blood cancers (AML, ALL and MDS). It will evaluate the safety of BSB-1001 and also determine whether it works to prevent relapse of your cancer.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
03/25/2025
Locations: City of Hope National Medical Center, Duarte, California
Conditions: AML, Adult Recurrent, ALL, Recurrent, Adult, MDS
Adjuvant Sacituzumab Govitecan and Nivolumab in Muscle-Invasive Urothelial Carcinoma At High-Risk Recurrence
Recruiting
This is a phase 2 study, single-arm study of adjuvant combination therapy with Sacituzumab Govitecan and Nivolumab in patients with muscle-invasive urothelial carcinoma of the bladder, ureter, or upper tract, who are high risk for cancer recurrence post curative-intent surgery based on surgical pathology.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, California
Conditions: Urothelial Carcinoma, Muscle-invasive Bladder Cancer
Improving Congenital Heart Disease Care
Recruiting
The theory-informed digital health intervention, called as "Empower My Congenital Health (EmpowerMyCH)" aims to activate and engage ACHD patients in building confidence toward navigating the adult healthcare system. This tool is built after incorporating the theories of behavior change, gathering inputs from target patients in all stages of its design and implementation. The key features of the tool include a digital medical passport, updated congenital information, community support, and patien... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: Congenital Heart Disease, Behavior, Health, Quality of Life, Empowerment, Patient, Activation, Patient
Ketogenic Diet and Brain Response in Anorexia Nervosa
Recruiting
This is a longitudinal study with an open design in weight recovered anorexia nervosa (wrAN) individuals. Healthy controls (HC) will also be assessed. Study participants will be carefully assessed and will have 18F-fluorodeoxyglucose (\[18F\]FDG) positron emission tomography (PET) scans for assessment of regional brain glucose uptake. The wrAN group will be compared to healthy controls. Participants in the wrAN group will then complete 14 weeks of therapeutic ketogenic diet (TKD). At the end of... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
03/25/2025
Locations: University of California San Diego, San Diego, California
Conditions: Anorexia Nervosa