California is currently home to 5602 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Individualized Neuroimaging Biomarkers for Predicting RTMS Response in OCD
NCT05829681
Recruiting
The goal of this clinical trial is to discover brain-based subtypes of Obsessive Compulsive Disorder (OCD) and examine treatment response to two different repetitive transcranial magnetic stimulation (rTMS) targets in the brain: the medial prefrontal cortex (MPFC) and the right prefrontal cortex (rPFC).
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/26/2024
Locations: Stanford University, Stanford, California
Conditions: Obsessive-Compulsive Disorder
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Effect of Meal Composition and Timing Modification on Glucose Metabolism, Body Temperature and Sleep
NCT05413928
Recruiting
The purpose of our study is to understand the impact of different meal timing alterations on blood sugars, metabolism, microbiome and sleep physiology in people with prediabetes and diabetes; and to study the temperature/heart rate response to different meals in different people.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/26/2024
Locations: Stanford University, Stanford, California
Conditions: PreDiabetes, Type 2 Diabetes, Healthy
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Machine Learning in Atrial Fibrillation
NCT05371405
Recruiting
Atrial fibrillation is a serious public health issue that affects over 5 million Americans (Miyazaka, Circulation 2006) in whom it may cause skipped beats, dizziness, stroke and even death. Therapy for AF is currently suboptimal, in part because AF represents several disease states of which few have been delineated or used to successfully guide management. This study seeks to clarify this delineation of AF types using machine learning (ML).
Gender:
ALL
Ages:
Between 22 years and 80 years
Trial Updated:
11/26/2024
Locations: Stanford University, Stanford, California
Conditions: Atrial Fibrillation, Arrhythmias, Cardiac
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The Dynamics of Human Atrial Fibrillation
NCT05366361
Recruiting
Atrial fibrillation (AF) is an enormous public health problem in the United States, affecting 2-5 million Americans and causing rapid heart beats, stroke, heart failure or death. In this project, the applicant will develop a novel framework to better understand human AF that builds on agreement between several concepts for the disease. The applicant will develop strategies to identify AF patients who will best respond to each of several therapies, to guide personalized therapy.
Gender:
ALL
Ages:
Between 22 years and 80 years
Trial Updated:
11/26/2024
Locations: Stanford University, Stanford, California
Conditions: Atrial Fibrillation, Arrhythmias, Cardiac
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A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)
NCT05230459
Recruiting
The purpose of this study is to evaluate the safety and tolerability of a single intravenous infusion of AB-1003 in adults diagnosed with limb girdle muscular dystrophy type 2I/R9 (LGMD2I/R9). Participants will be treated in sequential, dose-level cohorts. (Part 1)
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/26/2024
Locations: University of California - Irvine, Irvine, California
Conditions: Limb Girdle Muscular Dystrophy, Limb-Girdle Muscular Dystrophy Type 2, LGMD2I, Muscular Dystrophy, LGMD2, LGMD, FKRP, FKRP Mutation, Fukutin Related Protein
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AN/BN Risk Factors Study
NCT05133037
Recruiting
Across the United States, thousands of children and adolescents suffer from eating disorders. Among young women alone, an estimated 2 to 4 percent are dealing with anorexia nervosa. Anorexia nervosa also has the highest mortality rate of any psychiatric disorder and produces a six-fold increased risk for death. Unfortunately, study shows that current treatments are only successful with 25 percent of patients and no eating disorder prevention program has been found to reduce future onset of anore... Read More
Gender:
FEMALE
Ages:
Between 12 years and 16 years
Trial Updated:
11/26/2024
Locations: Stanford University, Stanford, California
Conditions: Eating Disorders
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Evaluating Genetic Modifiers of Cutaneous Neurofibromas in Adults with Neurofibromatosis Type 1
NCT04941027
Recruiting
The main goal of this protocol is to develop a well-phenotyped genetic biobank to identify genetic variants associated with the heterogeneous clinical presentations of Neurofibromatosis Type 1 (NF1). This will allow for improve understanding of NF1 pathogenesis and more personalized disease management. The investigators will conduct a GWAS analysis to identify common genetic risk variants associated with the development of cutaneous neurofibromas.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
11/26/2024
Locations: Johns Hopkins University School of Medicine, Baltimore, California
Conditions: Neurofibromatosis 1
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Evaluation of the Effects of a Rehabilitation Program in Individuals with Spine Pain
NCT04081896
Recruiting
SpineZone is an innovative physical therapy program with its focus on treatment of cervical, thoracic, and lumbar conditions through the use of a multi-disciplinary, technology enabled platform. Standard physical therapy modalities including psychologically informed physical therapy are employed in addition to online coaching with a fundamental tenant of core strengthening. Treatments are tracked and modified in a multi-disciplinary format taking all radiographic studies into direct consideratio... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
11/26/2024
Locations: SpineZone, San Diego, California
Conditions: Neck Pain, Low Back Pain, Scoliosis, Thoracic Injuries
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Caloric Vestibular Stimulation for Modulation of Insight in Obsessive-Compulsive Spectrum Disorders
NCT03918577
Recruiting
This study investigates whether caloric vestibular stimulation can modulate a measure of insight in obsessive-compulsive spectrum disorders.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/26/2024
Locations: Stanford University, Stanford, California
Conditions: Obsessive-Compulsive Disorder, Body Dysmorphic Disorders, Illness Anxiety Disorder
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Efficacy of Nitrous Oxide in OCD: Pilot Study
NCT03826693
Recruiting
This study investigates whether the commonly used and well-tolerated inhaled anesthetic nitrous oxide can rapidly improve symptoms of OCD.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/26/2024
Locations: Stanford University, Stanford, California
Conditions: Obsessive-Compulsive Disorder
Register for Updates
A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee
NCT03588975
Recruiting
The objective of this study is to compare the efficacy and safety of MACI® vs arthroscopic microfracture in the treatment of patients aged 10 to 17 years with symptomatic articular chondral or osteochondral defects of the knee.
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
11/26/2024
Locations: Stanford University, Palo Alto, California
Conditions: Chondral Defect, Articular Cartilage Defect, Articular Cartilage Disorder of Knee, Osteochondritis Dissecans (OCD)
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Immunologic Response to Pneumococcal Polysaccharide Vaccine in Splenic Injury Patients
NCT02232191
Recruiting
Persons without a spleen are susceptible to potentially lethal infections from certain bacteria, with pneumococcus being the most prevalent. Vaccines are provided to help protect against these infections, though they do not so with certainty. Trauma patients who sustain an injury to their spleen currently have three treatment options available for the treating surgeon - nonoperative management, embolization, or removal of the spleen. The purpose of this study is to investigate the antibody respo... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/26/2024
Locations: University of California, Davis Medical Center, Sacramento, California
Conditions: Asplenia
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