California is currently home to 5600 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Brain Health Virtual Reality Study
Recruiting
The Interventions for Brain Health Virtual Reality Study is a NIH-funded clinical research trial at the University of California San Diego (UCSD) Health under the supervision of the study principal investigator Dr. Judy Pa. The overarching goal of this trial is to use a novel virtual reality (VR) based intervention that simultaneously engages physical and cognitive activity aimed at improving brain health and cognition in older adults. The investigators will compare 3 types of interventions: phy... Read More
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
07/08/2024
Locations: University of California, San Diego, San Diego, California
Conditions: Aging, Aging Problems, Memory Loss, Memory Impairment, Memory Disorders in Old Age, Memory Disorder, Spatial, Memory Disorders, Mild Cognitive Impairment, Cognitive Decline, Cognitive Change, Cognition Disorders in Old Age
FOOD PRESCRIPTION APP
Recruiting
This study will develop and test and app that will create meal plans to improve diet quality and support weight loss. This app will allow participants to customize their meal plans and substitute recipes for nutritionally equivalent options that they find more appealing, thus potentially increasing adherence.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2024
Locations: Kaiser Permanente, Pasadena, California
Conditions: Diet, Healthy
GOLD: Brief Intervention to Reduce Anxiety and Promote Resilience in Families of Youth With Cancer
Recruiting
The purpose of this study is to examine a psychotherapeutic and psycho-educational intervention offered in virtual settings to caregivers of youth with cancer. Human subjects must be used because they are the object of the intervention.
Gender:
ALL
Ages:
Between 8 years and 18 years
Trial Updated:
07/08/2024
Locations: Stanford Cancer Institute, San Francisco, California
Conditions: Cancer
Endoscopic Evidence of Maintenance of Healing With Oral NEXIUM in Patients 1 to 11 Years Old With Erosive Esophagitis.
Recruiting
The aim of the study is to compare the safety and efficacy of two doses of Nexium in maintaining healing of erosive esophagitis in patients 1 to 11 years of age.
Gender:
ALL
Ages:
Between 1 year and 11 years
Trial Updated:
07/08/2024
Locations: Research Site, Fontana, California
Conditions: Erosive Esophagitis
Luteolin for the Treatment of People With Schizophrenia
Recruiting
Luteolin is a natural product found in foods such as celery, green pepper, parsley, and chamomile tea. It has been found to have anti-cancer, anti-oxidant, and anti-inflammatory properties. The purpose of this study is to determine if luteolin helps improve symptoms of schizophrenia.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
07/08/2024
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Schizophrenia, Schizoaffective Disorder
ACT1VATE: Addressing Emotional Distress to Improve Outcomes Among Diverse Adults With Type 1 Diabetes
Recruiting
This research will compare a psychological intervention ("ACT1VATE") versus diabetes self-management education and support (DSME/S; usual care) in improving clinical, behavioral, psychosocial, process, and cost outcomes among adults with poorly controlled type 1 diabetes (T1D) who are experiencing significant diabetes-related emotional distress and poor glycemic control in a real world, healthcare environment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2024
Locations: Scripps Whittier Diabetes Institute, San Diego, California
Conditions: Type 1 Diabetes
Impact of Prebiotics in Ulcerative Colitis
Recruiting
The cause of inflammatory bowel disease (IBD) is currently unknown, although partly attributed to interactions among genetic risk polymorphisms, environmental factors, gut microbiome, and host immunity. Diet, particularly those with plant-based products, have been shown in prior research to improve gut microbial composition, which has been linked to different IBD-related outcomes. This study is interested in evaluating the impact of prebiotics on gut microbiome composition and gut health in pati... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
07/07/2024
Locations: UCLA, Los Angeles, California
Conditions: Crohn Disease, Ulcerative Colitis
Study of ALTO-300 in MDD
Recruiting
The purpose of this study is to determine efficacy differences between ALTO-300 and placebo, used adjunctively to an antidepressant, related to patient characteristics.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/05/2024
Locations: Site 218, Bellflower, California
Conditions: Major Depressive Disorder
Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation
Recruiting
This phase II trial tests how well carboplatin before surgery works in treating patients with high-risk prostate cancer and an inherited BRCA1 or BRCA2 gene mutation. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping, or slowing the growth of tumor cells. Giving carboplatin before surgery may shrink tumors in patients with h... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
07/05/2024
Locations: Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande, California
Conditions: Prostate Adenocarcinoma, Stage IIIB Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
Recruiting
Post-traumatic stress disorder (PTSD) is a common consequence of combat that can result in trauma-related hyperarousal and sleep disturbances. Poor sleep, one of the most common complaints in Veterans with PTSD, can be distressing, impair concentration and memory, and contribute to physical health conditions, such as metabolic syndrome, inflammation, and cardiovascular disease. The orexin neuropeptide system underlies both sleep and stress reactivity. Suvorexant, a drug that reduces orexin, impr... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/05/2024
Locations: VA Long Beach Healthcare System, Long Beach, CA, Long Beach, California
Conditions: Sleep Initiation and Maintenance Disorders, Stress Disorders, Posttraumatic
Centralized Virtual SBIRT for Pediatric Primary Care
Recruiting
Adolescent alcohol and other drug (AOD) use is a significant public health problem which contributes to high levels of mortality, morbidity and healthcare costs in young people, and identification and early intervention for these problems is critical to improving outcomes. Screening, Brief Intervention and Referral to Treatment (SBIRT) in pediatric primary care is an evidence-based strategy for addressing these problems, but has not been widely and systematically implemented, for a variety of re... Read More
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
07/04/2024
Locations: Kaiser Permanente Division of Research, Pleasanton, California
Conditions: Adolescent Alcohol Use, Mental Health Issue, Alcohol Related Disorders, Adolescents
Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
Recruiting
Skeletal muscle metabolic health is critical for mobility and an underrecognized target of metabolic acidosis in chronic kidney disease. Impaired muscle mitochondrial metabolism underlies poor physical endurance increasing the risk of mobility disability. The proposed project will use precise in vivo tools to study the pathophysiology of poor physical endurance in a clinical trial treating metabolic acidosis among persons living with chronic kidney disease.
Gender:
ALL
Ages:
Between 21 years and 85 years
Trial Updated:
07/04/2024
Locations: University of California Davis Health, Sacramento, California
Conditions: Chronic Kidney Diseases, Metabolic Acidosis, Fatigue, Physical Endurance, Insulin Resistance, Mitochondrial Energetics, Diabetes