California is currently home to 5590 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Trial
Recruiting
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise for reducing symptom severity in recent small-scale trials. The findings from this research will shed light on the mechanisms of action underlying the clinical benefits of NAC and the effects of NAC on altering restricted and repetitive behavior symptom severity in childre... Read More
Gender:
ALL
Ages:
Between 3 years and 12 years
Trial Updated:
07/23/2024
Locations: Department of Psychiatry and Behavioral Sciences, Palo Alto, California
Conditions: Autism Spectrum Disorder
Healthcare Providers as Trusted Messengers to Increase Receipt of Tax Credits Among Low-income Families
Recruiting
The purpose of this study is to pilot test the feasibility, acceptability, and preliminary efficacy of healthcare provider referrals to a tax filing app within parent-child health programs to test whether such referrals can increase receipt of tax credits among low-income parents. The study will use a single-group, pre/post test design with a sample of approximately 100 women who have a child under 6 years of age. Participants will be recruited from parental-child health programs and clinics in... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
07/23/2024
Locations: UCLA School of Nursing, Los Angeles, California
Conditions: Depression, Child Development, Stress, Physical Illness, Health Care Utilization
S.T.A.N.D. Alacrity Center Signature Project
Recruiting
The purpose of this study is to evaluate clinical decision-making algorithms for (a) triaging to level of care and (b) adapting level of care in a low income, highly diverse sample of community college students at East Los Angeles College (ELAC). The target enrollment is 200 participants per year, for five years (N=1000). Participants are between the ages of 18 and 40 years and will be randomized into either symptom severity decision-making (SSD) or data-driven decision-making (DDD). Participan... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
07/23/2024
Locations: East Los Angeles College, Los Angeles, California
Conditions: Depression, Anxiety
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Single-dose
Recruiting
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise for reducing symptom severity in recent small-scale trials. The findings from this research will shed light on the mechanisms of action underlying the clinical benefits of NAC.
Gender:
ALL
Ages:
Between 3 years and 12 years
Trial Updated:
07/23/2024
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Autism Spectrum Disorder
Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Recruiting
A multicenter, open-label Phase 2b study of selinexor (KPT-330) in participants with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who have no therapeutic options of demonstrated clinical benefit.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: University of California San Francisco, San Francisco, California
Conditions: Diffuse Large B-cell Lymphoma
Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea
Recruiting
Prospective, interventional cohort study of drug-induced sleep endoscopy (DISE) to evaluate the upper airway in a cohort of obstructive sleep apnea (OSA) surgical patients. This study has investigated the reliability of this technique, demonstrating moderate-substantial interrater and test-retest reliability. This research has also compared DISE findings to those of the lateral cephalogram X-ray and examined DISE findings in individuals who have not responded to previous sleep apnea surgery. The... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: UCLA Santa Monica Medical Center, Santa Monica, California
Conditions: Sleep Apnea, Obstructive
Study Assessing Complete Wound Healing by Comparing Surgenex® PelloGraft in Treating DFU and SanoGraft® in Treating VLU to SOC
Recruiting
The purpose of this study is to compare Pellograft to standard of care modalities in treating diabetic foot ulcers in human subjects, and to compare Sanograft to standard of care in treating venous leg ulcers. The study will demonstrate wound healing outcomes with comparators including time to wound epithelialization, decrease in wound size, and total number of study product applications towards healing outcome. This information is important to the Centers for Medicare and Medicaid Services (CMS... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2024
Locations: ILD Research, Vista, California
Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer
Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial
Recruiting
This research is to evaluate the effectiveness of Talazoparib as a potential treatment for metastatic breast cancer with a BRCA 1 or BRCA 2 mutation.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/22/2024
Locations: UCSF Medical Center-Mission Bay/Benioff Children's Hospital, San Francisco, California
Conditions: Breast Cancer
Mechanistic Insights From Bronchoscopy Airway Samples
Recruiting
The purpose of this study is to examine the mechanisms of asthma. The investigators are comparing the cells of individuals with and without asthma and looking at the roles various parts of the cell play in the production and secretion of mucus.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/19/2024
Locations: University of California, San Francisco, San Francisco, California
Conditions: Asthma
Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
Recruiting
The hypothesis for this study is that a preparative regimen that maximizes host immunosuppression without myeloablation will be well tolerated and sufficient for engraftment of donor hematopoietic cells. It is also to determine major toxicities from these conditioning regimens, within the first 100 days after transplantation.
Gender:
ALL
Ages:
20 years and below
Trial Updated:
07/19/2024
Locations: Children's Hospital of Orange County, Orange, California
Conditions: Metabolic Disorders, Hematologic, Immune, or Bone Marrow Disorders, Hemoglobinopathies, Non-malignant Disorders
Comparing Different Rehabilitation Exercise Strategies for Improving Arm Recovery After Stroke
Recruiting
The purpose of this research study is to measure the effect of participating in extra arm exercise in addition to standard rehabilitation exercises in the Acute Rehabilitation Unit. This study will compare two different ways to perform the extra arm exercise. The first is following a customized program of hand and arm exercises that will be developed for study participants by an experienced rehabilitation therapist. The second is moving a participants arm back and forth when they are sitting in... Read More
Gender:
ALL
Ages:
Between 18 years and 84 years
Trial Updated:
07/18/2024
Locations: Rancho Research Institute, Downey, California
Conditions: Stroke
Effect of a Fasting Mimicking Diet on Patients With Multiple Sclerosis (FMDMS)
Recruiting
In the proposed study, investigators will assess the safety and feasibility of cycles of a fasting mimicking diet (FMD) and its effect on Multiple Sclerosis Quality of Life (MSQOL) in relapsing MS (RMS) patients treated with standard disease modifying therapies (FMDMS). To test the primary hypothesis, investigators will compare the composite quality of life score in terms of improvement in disability, fatigue, and cognitive function with the fasting protocol, as compared to a Mediterranean diet... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/17/2024
Locations: Keck School of Medicine of the University of Southern California, Los Angeles, California
Conditions: Multiple Sclerosis