California is currently home to 5610 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Web-based Program to Improve Self-management Among Veterans-caregiver Dyads
Recruiting
The majority of Veterans will suffer from at least one chronic illness, often at great emotional and personal cost. Self-management is critical to improving physical and emotional outcomes, and many chronically ill Veterans receive self-management assistance from an informal caregiver, and both Veterans and informal caregivers experience individual and interpersonal stress as they navigate this journey. Yet, current clinical practices are not designed to effectively support the needs of both Vet... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/31/2024
Locations: VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto, California
Conditions: Chronic Medical Conditions
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
Recruiting
A prospective, single-arm, multi-center study designed to gather additional information on the LimFlow System.
Gender:
ALL
Ages:
Between 18 years and 95 years
Trial Updated:
05/31/2024
Locations: University of California, San Diego Health, La Jolla, California
Conditions: Critical Limb Ischemia, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit)
Recruiting
This clinical trial studies the effect of four different intervention components "tools" on body weight, nutrition, and physical activity in cancer survivors. Studies indicate that people with a history of cancer whose nutrition and physical activity habits are consistent with the American Cancer Society's Nutrition and Physical Activity Guidelines may have longer disease-free survival. The four different intervention components may help patients with a history of cancer adopt recommended health... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/30/2024
Locations: University of California San Francisco, San Francisco, California
Conditions: Bladder Cancer, Breast Cancer, Colon Cancer, Endometrial Cancer, Ovarian Cancer, Rectal Cancer, Prostate Cancer, Renal Cell Carcinoma, Kidney Cancer
Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)
Recruiting
BK cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be safe and effective in decreasing specific viral load in children, adolescents and young adults (CAYA) with refractory BK infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT) or with primary immunodeficiencies (PID).
Gender:
ALL
Ages:
Between 1 month and 79 years
Trial Updated:
05/30/2024
Locations: University of California San Francisco, San Francisco, California
Conditions: Viral Infection, Primary Immune Deficiency Disorder
Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer
Recruiting
The purpose of this research study is to compare the effects (good and bad) on women and their cancer using proton radiation therapy. This study is being done to see if proton radiation therapy will prove to be beneficial for women with early stage breast cancer. A clinical study is necessary to compare the results (good or bad) of proton radiation therapy.
Gender:
FEMALE
Ages:
50 years and above
Trial Updated:
05/30/2024
Locations: California Protons Cancer Therapy Center, San Diego, California
Conditions: Breast Cancer, Breast Neoplasm, Breast Tumor, Cancer of the Breast
Registry Study for Radiation Therapy Outcomes
Recruiting
The purpose of this research study is to collect and analyze information from patients being treated with various forms of radiation therapy.
Gender:
ALL
Ages:
All
Trial Updated:
05/30/2024
Locations: California Protons Cancer Therapy Center, San Diego, California
Conditions: Neoplasms
Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma
Recruiting
This study is a Phase 1 multicenter study with a Dose Escalation and Dose Expansion evaluating safety and efficacy of MT-601 administration to patients with Relapsed or Refractory Lymphoma. The starting dose administered is 200 x 10\^6 cells (flat dosing).
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
05/29/2024
Locations: City of Hope, Duarte, California
Conditions: Non-Hodgkin Lymphoma, Adult, Non-Hodgkin Lymphoma, Refractory, Non-Hodgkin Lymphoma, Relapsed, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Hodgkin Lymphoma, Adult, Hodgkin's Lymphoma, Relapsed, Adult
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer
Recruiting
To goal of this clinical trial is to quantify the dose-response effects of aerobic exercise training compared to attention control on chemotherapy relative dose intensity in colon cancer survivors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/29/2024
Locations: Kaiser Permanente Northern California, Oakland, California
Conditions: Colonic Neoplasms
Dulce Digital 2.0 - Innovative Diabetes Self-Management in the Digital Age
Recruiting
The proposed research, "Dulce Digital 2.0," will evaluate two mHealth adaptions of Project Dulce that are designed to improve digital health literacy, increase underserved individuals' capacity to access and engage with vital digital health information, and in turn, improve clinical and behavioral outcomes in at-risk adults with diabetes. Expanding access to care in populations faced with challenges of low socioeconomic status and health literacy is a step toward reducing health disparities and... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/29/2024
Locations: Scripps Chula Vista Diabetes Center, Chula Vista, California
Conditions: Diabetes Type 2
Elbow Artery Embolization for Tennis Elbow
Recruiting
The purpose of this clinical research study is to examine whether embolization treatment of an elbow artery is a safe and effective way to treat elbow pain, specifically pain from tennis elbow. Embozene is a medical device made by Varian marketed in the United States for the treatment of hypervascular tumors and arteriovenous malformations. It consists of thousands of microscopic spheres that are injected into the artery to block the flow of blood to a specific region. One of the causes of pain... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/29/2024
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Lateral Epicondylitis, Unspecified Elbow
Open-Label, Dose-Escalation With Expansion to Assess the Safety, Tolerability, and PK of TRE-515 in Subjects With Solid Tumors
Recruiting
TRE-515 is a first-in-class small molecule inhibitor of deoxycytidine kinase (dCK) that is being developed for oral administration in patients with solid tumors. In cancer cells, rapid and upregulated DNA replication creates high replication stress, as such, cancer cells are more susceptible than normal cells to perturbations in nucleotide metabolism by DNA-targeting treatments such as TRE-515. The Primary objective is too determine the safety and maximum tolerability of TRE-515 when administer... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/29/2024
Locations: UCLA, Santa Monica, California
Conditions: Solid Tumor, Adult, Oncology
Biology and Benefits of Music Play and Stories for Kids/Parents During ALL Treatment
Recruiting
Music therapy has become a standard palliative care service in many pediatric and adult hospitals; however, a majority of music therapy research has focused on the use of music to improve psychosocial dimensions of health, without considering biological dimensions. This study builds on prior work examining the psychosocial mechanisms of action underlying an Active Music Engagement (AME) intervention, designed to help manage emotional distress and improve positive health outcomes in young childre... Read More
Gender:
ALL
Ages:
Between 3 years and 8 years
Trial Updated:
05/29/2024
Locations: UCSF Benioff Children's Hospital, Oakland, California
Conditions: Acute Lymphoblastic Leukemia, Pediatric, Pediatric Cancer