California is currently home to 5592 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
FOOD PRESCRIPTION APP
Recruiting
This study will develop and test and app that will create meal plans to improve diet quality and support weight loss. This app will allow participants to customize their meal plans and substitute recipes for nutritionally equivalent options that they find more appealing, thus potentially increasing adherence.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2024
Locations: Kaiser Permanente, Pasadena, California
Conditions: Diet, Healthy
GOLD: Brief Intervention to Reduce Anxiety and Promote Resilience in Families of Youth With Cancer
Recruiting
The purpose of this study is to examine a psychotherapeutic and psycho-educational intervention offered in virtual settings to caregivers of youth with cancer. Human subjects must be used because they are the object of the intervention.
Gender:
ALL
Ages:
Between 8 years and 18 years
Trial Updated:
07/08/2024
Locations: Stanford Cancer Institute, San Francisco, California
Conditions: Cancer
Endoscopic Evidence of Maintenance of Healing With Oral NEXIUM in Patients 1 to 11 Years Old With Erosive Esophagitis.
Recruiting
The aim of the study is to compare the safety and efficacy of two doses of Nexium in maintaining healing of erosive esophagitis in patients 1 to 11 years of age.
Gender:
ALL
Ages:
Between 1 year and 11 years
Trial Updated:
07/08/2024
Locations: Research Site, Fontana, California
Conditions: Erosive Esophagitis
Study of ALTO-300 in MDD
Recruiting
The purpose of this study is to determine efficacy differences between ALTO-300 and placebo, used adjunctively to an antidepressant, related to patient characteristics.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/05/2024
Locations: Site 218, Bellflower, California
Conditions: Major Depressive Disorder
Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation
Recruiting
This phase II trial tests how well carboplatin before surgery works in treating patients with high-risk prostate cancer and an inherited BRCA1 or BRCA2 gene mutation. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping, or slowing the growth of tumor cells. Giving carboplatin before surgery may shrink tumors in patients with h... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
07/05/2024
Locations: Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande, California
Conditions: Prostate Adenocarcinoma, Stage IIIB Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
Recruiting
Post-traumatic stress disorder (PTSD) is a common consequence of combat that can result in trauma-related hyperarousal and sleep disturbances. Poor sleep, one of the most common complaints in Veterans with PTSD, can be distressing, impair concentration and memory, and contribute to physical health conditions, such as metabolic syndrome, inflammation, and cardiovascular disease. The orexin neuropeptide system underlies both sleep and stress reactivity. Suvorexant, a drug that reduces orexin, impr... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/05/2024
Locations: VA Long Beach Healthcare System, Long Beach, CA, Long Beach, California
Conditions: Sleep Initiation and Maintenance Disorders, Stress Disorders, Posttraumatic
Centralized Virtual SBIRT for Pediatric Primary Care
Recruiting
Adolescent alcohol and other drug (AOD) use is a significant public health problem which contributes to high levels of mortality, morbidity and healthcare costs in young people, and identification and early intervention for these problems is critical to improving outcomes. Screening, Brief Intervention and Referral to Treatment (SBIRT) in pediatric primary care is an evidence-based strategy for addressing these problems, but has not been widely and systematically implemented, for a variety of re... Read More
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
07/04/2024
Locations: Kaiser Permanente Division of Research, Pleasanton, California
Conditions: Adolescent Alcohol Use, Mental Health Issue, Alcohol Related Disorders, Adolescents
Creatine Supplementation At Simulated Altitude
Recruiting
Creatine supplementation has been shown to increase exercise performance at sea level. The goal of this study is to determine the effects of creatine supplementation on exercise performance at simulated altitude.
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
07/03/2024
Locations: California Polytechnic State University, San Luis Obispo, California
Conditions: Exercise Performance
Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy
Recruiting
This clinical trial tests how well a geriatric assessment (GA) with GA-directed treatment recommendations, compared to GA with usual care, works in identifying risk factors, reducing chemotherapy radiation toxicity and functional decline, and improving the overall quality of life in older patients with non-small cell lung cancer (NSCLC). Older patients with lung cancer undergoing chemotherapy are at an increased risk of adverse outcomes including treatment toxicity and functional and physical co... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
07/02/2024
Locations: City of Hope Medical Center, Duarte, California
Conditions: Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8
Personalized Accelerated ChEmoRadiation (PACER) for Lung Cancer
Recruiting
The purpose of this study is to examine the use of hypofractionated accelerated radiation therapy (HART) to treat locally advanced lung cancer. Depending on the location and size of the tumor.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/02/2024
Locations: Stanford University, Palo Alto, California
Conditions: Lung Cancer
LINNOVATE: Lurbinectedin, Ipilimumab and Nivolumab for Soft Tissue Sarcoma
Recruiting
This is an open label, dose-seeking phase 1/2 study using escalating doses of LURBINECTEDIN administered intravenously with fixed doses of IPILIMUMAB and NIVOLUMAB administered intravenously.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
07/02/2024
Locations: Sarcoma Oncology Research Center, Santa Monica, California
Conditions: Advanced Soft-tissue Sarcoma
A Study of Vibegron in Pediatric Participants 2 Years to Less Than (<) 18 Years of Age With NDO and on CIC
Recruiting
The purpose of this study is to evaluate the safety, efficacy, and PK of vibegron in pediatric participants with NDO who are regularly using CIC
Gender:
ALL
Ages:
Between 2 years and 17 years
Trial Updated:
07/02/2024
Locations: Children's Hospital of Orange County, Orange, California
Conditions: Neurogenic Detrusor Overactivity