Colorado is currently home to 1917 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Effects of IV vs Oral Dexamethasone on Postoperative Nausea, Vomiting, and Pain
NCT04563494
Recruiting
The hypothesis being tested in this study is that perioperative oral administration of dexamethasone, when compared to intravenous (IV) administration, offers a similar reduction in postoperative nausea and vomiting (PONV), and reduction in postoperative pain in pediatric patients undergoing tonsillectomy with or without adenoidectomy and/or tympanostomy tube placement. The specific aim of this study is to demonstrate non-inferiority of oral dexamethasone when compared to IV dexamethasone, given... Read More
Gender:
All
Ages:
Between 3 years and 7 years
Trial Updated:
01/17/2023
Locations: Children's Hospital of Colorado, Aurora, Colorado
Conditions: Nausea and Vomiting, Postoperative
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MARS MRI in Revision THA With a Ceramic Femoral Head and Titanium Sleeve
NCT05686915
Recruiting
Revision total hip replacement using a ceramic head utilizes a titanium sleeve which introduced another articulation into the system that may lead to a local soft tissue reaction. The purpose of this study is to determine the frequency, size and types of MRI documented local tissue reactions in individuals doing well after a revision total hip replacement and ceramic bearing surface that utilizes a titanium sleeve.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
01/13/2023
Locations: Colorado Joint Replacement, Denver, Colorado
Conditions: Arthroplasty, Replacement, Hip
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SARC041: Study of Abemaciclib Versus Placebo in Patients With Advanced Dedifferentiated Liposarcoma
NCT04967521
Recruiting
This is a Phase 3 randomized double-blind study of abemaciclib versus placebo. Patients with progression of disease will cross over to open label abemaciclib.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2023
Locations: University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, Colorado
Conditions: Advanced Dedifferentiated Liposarcoma
Register for Updates
Rett Syndrome Registry
NCT05432349
Recruiting
The Rett Syndrome Registry is a longitudinal observational study of individuals with MECP2 mutations and a diagnosis of Rett syndrome. Designed together with the IRSF Rett Syndrome Center of Excellence Network medical directors, this study collects data on the signs and symptoms of Rett syndrome as reported by the Rett syndrome experts and by the caregivers of individuals with Rett syndrome. This study will be used to develop consensus based guidelines for the care of your loved ones with Rett s... Read More
Gender:
All
Ages:
Between 0 years and 99 years
Trial Updated:
01/09/2023
Locations: Children's Hospital Colorado, Denver, Colorado
Conditions: Rett Syndrome, Rett Syndrome, Atypical, Genetic Disease, Genetic Diseases, X-Linked, Intellectual Disability, Neurobehavioral Manifestations, Neurologic Manifestations, Neurologic Disorder, Neurodevelopmental Disorders, Nervous System Diseases
Register for Updates
Effects of Complementary Feeding on Infant Growth and Gut Health
NCT05012930
Recruiting
This study plans to learn more about how consuming different foods during the time of early complementary feeding (~5 to 12 months) affects growth and the development of bacteria living inside your baby's gut. The results from this study will potentially help to support future recommendations and dietary guidance for infant feeding practices. The three primary aims include: Aim 1. Identify the impact of dietary patterns with different protein-rich foods on infant growth. Aim 2. Identify the i... Read More
Gender:
All
Ages:
Between 4 months and 50 months
Trial Updated:
01/09/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Gut Microbiome, Linear Growth
Register for Updates
A RCT Comparing Dronabinol to a Placebo for Post-operative Pain in Total Joint Arthroplasty
NCT04298528
Recruiting
The primary purpose of this study was to determine if cannabinoid use decreases narcotic consumption in patients undergoing total knee arthroplasty (TKA).
Gender:
All
Ages:
Between 21 years and 75 years
Trial Updated:
01/06/2023
Locations: Colorado Joint Replacement, Denver, Colorado
Conditions: Osteoarthritis, Knee
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Cutibacterium Dermal Colonization: Implications for Total Hip Arthroplasty
NCT03849885
Recruiting
This study is being done to investigate the colonization rate(growth rate) of a particular type of low-virulence (does not typically cause infection) bacterium called Propionibacterium, more specifically P acnes, the same bacterium that is responsible for the majority of acne. Information affecting hip surgery is currently unknown.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
01/06/2023
Locations: Colorado Joint Replacement, Denver, Colorado
Conditions: Degenerative Osteoarthritis
Register for Updates
Dose Escalation and Dose Expansion Study of CPO-100 in Patients With Advanced Solid Tumors
NCT04931823
Recruiting
This is a Phase 1, multicenter, open-label, dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics, and preliminary evidence of antitumor activity of CPO-100 administered intravenously in cycles of 3 weekly doses with 1 week rest (1 cycle = 4 weeks) in adult patients with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/16/2022
Locations: University of Colorado Denver, Denver, Colorado
Conditions: Solid Tumor
Register for Updates
Oscillating Positive Expiratory Pressure (OPEP) Therapy in Trauma Patients With Multiple Rib Fractures
NCT04100512
Recruiting
To determine the efficacy of oscillatory positive expiratory pressure (OPEP) therapy on patients admitted through the trauma service line for rib fractures, as compared to incentive spirometry (IS).
Gender:
All
Ages:
18 years and above
Trial Updated:
12/15/2022
Locations: Medical Center of the Rockies, Loveland, Colorado
Conditions: Rib Fractures, Respiratory Complication
Register for Updates
Dental Appliance to Treat SDB in Children
NCT05661747
Recruiting
The clinical hypothesis of this study is that a currently marketed mouthguard may also be able to reduce the symptoms of sleep-disordered breathing in children.
Gender:
All
Ages:
Between 7 years and 17 years
Trial Updated:
12/14/2022
Locations: Breathing and Sleep Center, Colorado Springs, Colorado
Conditions: Snoring, Apnea, Obstructive, Upper Airway Resistance Syndrome, Sleep-Disordered Breathing
Register for Updates
Blood Samples for the Study of Peanut, Tree Nut and Other Food Allergies
NCT02192866
Recruiting
Food allergies are now a major problem. These experiments involve getting blood from people with food allergies and from people without food allergies. The blood collected will be used to answer questions and find information about peanut and other food allergies. Samples will come from: People signed up by the investigators at the University of Colorado Denver University of North Carolina, Massachusetts General Hospital, Children's Hospital of Colorado and the Immune Tolerance Network (Benaro... Read More
Gender:
All
Ages:
Between 1 year and 75 years
Trial Updated:
12/14/2022
Locations: University of Colorado School of Medicine, Denver, Colorado
Conditions: Peanut Allergies, Tree Nut Allergies, Other Food Allergies
Register for Updates
International Weight Control Registry
NCT04907396
Recruiting
The IWCR is a global scientific study aimed at better understanding the opportunities and barriers for reducing the prevalence of obesity by collecting information from people who have experience with weight management in their everyday lives. The investigators seek to gather information on a wide range of weight management experiences, ranging from weight loss and weight loss maintenance to weight gain and inability to lose weight.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/07/2022
Locations: University of Colorado, Denver, Denver, Colorado
Conditions: Weight Loss, Overweight, Obesity
Register for Updates