Colorado is currently home to 1915 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Genetics of QT Prolongation With Antiarrhythmics
NCT02439658
Recruiting
To assess the ability of common genetic variants in aggregate to predict drug-induced QT prolongation in patients being loaded with dofetilide or sotalol.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/25/2022
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Long QT Syndrome, Drug Toxicity
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Molecular Endotypes of Chronic Idiopathic Urticaria
NCT04774315
Recruiting
This study plans to learn more about why some people with Chronic Idiopathic Urticaria (CIU) respond to treatment with omalizumab (Xolair). It will test people before they receive treatment with omalizumab as part of standard of care, to see if there are differences in their blood and skin that can predict who responds to treatment.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/23/2022
Locations: University of Colorado Anschutz, Aurora, Colorado
Conditions: Chronic Urticaria, Idiopathic
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NA-AION Risk Factors: New Perspectives
NCT05305079
Recruiting
The purpose of the study is to use new diagnostic methods (OCT and OCT-A) to shed light on risk factors for the development of NA-AION. The risk factors we are focusing on are comorbidities along with anatomical and vascular characteristics of the optic nerve.
Gender:
All
Ages:
11 years and above
Trial Updated:
03/22/2022
Locations: University og Colorado, Boulder, Colorado
Conditions: Non-arteritic Ischemic Optic Neuropathy, Optic Disk Drusen
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A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors
NCT04045496
Recruiting
This is a Phase 1, first-in-human, open-label dose-escalation study to determine the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) and assess the DLT of JAB-3312. It is anticipated that approximately 24 subjects will be enrolled in the dose-escalation phase of the study. JAB-3312 will be administered orally once daily (QD) in 21-day treatment cycles.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/13/2022
Locations: HealthONE Clinic Services Oncology-Hematology, Denver, Colorado
Conditions: Non-small Cell Lung Cancer, Colorectal Cancer, Pancreatic Ductal Carcinoma, Esophageal Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma, Breast Cancer, Other Solid Tumors
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A First-in-Human Study of JAB-8263 in Adult Patients With Advanced Solid Tumors
NCT04587479
Recruiting
This is a Phase 1, first-in-human, open-label study of JAB-8263 to determine the maximum tolerated dose (MTD), recommended Phase 2 dose (RP2D) and assess the DLT. 30 subjects with advanced solid tumor will be enrolled.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2022
Locations: SCRI HeatlthONE, Denver, Colorado
Conditions: Solid Tumors, Adult
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COVID-19 Diagnostic Self-testing Using Virtual Point-of-care
NCT04348864
Recruiting
The goal of the research is to assess candidate COVID-19 rapid diagnostic tests (e.g. immunodiagnostic antibody tests, like Cellex qSARS-CoV-2 IgG/IgM Rapid Test, or antigen tests, like Turklab Test-It COVID-19 Home Test, AllBio Science Inc. and Artron Laboratories Inc. rapid COVID-19 antigen tests in order to judge their clinical accuracy compared to Centers for Disease Control (CDC)-recommended molecular genetic testing and clinical diagnosis. Second, it is our goal to determine if self-testin... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
03/08/2022
Locations: Neuroganics, Northglenn, Colorado
Conditions: Communicable Disease, COVID-19, Sars-CoV2, Infectious Disease, Coronavirus, Virus
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Prospective Global Registry for the Study of Chronic Total Occlusion Intervention
NCT02061436
Recruiting
Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is increasingly being performed in patients with advanced coronary artery disease, but there is limited information on the techniques utilized and the procedural outcomes. The goal of this multicenter, investigator initiated registry is to collect information on treatment strategies and outcomes of consecutive patients undergoing CTO PCI among various participating centers. The information collected will be used to deter... Read More
Gender:
All
Ages:
All
Trial Updated:
03/08/2022
Locations: Medical Center of the Rockies, Loveland, Colorado
Conditions: Coronary Artery Disease
Register for Updates
National Vaccine Adverse Event Reporting Survey and Etiology
NCT05095844
Recruiting
If your serious vaccine-induced adverse event has been entered in the CDC Vaccine Adverse Event Reporting System (VAERS) we are interested in enrolling you for this study in order to log your symptoms. The primary goal of this study is to create a national database and gather vaccine-associated serious adverse events/injury data from newly vaccinated individuals in the US in order to identify the possible underlying causal relationships and plausible underlying biological mechanisms. The projec... Read More
Gender:
All
Ages:
Between 5 years and 99 years
Trial Updated:
03/03/2022
Locations: Neuroganics LLC, Northglenn, Colorado
Conditions: COVID-19, Vaccine Adverse Reaction, Vaccine Reaction, Vaccine or Biological Substance, Unspecified Causing Adverse Effects in Therapeutic Use, Corona Virus Infection, Blood Clot, Thrombocytopenia, Neuritis, Vasculitis, Influenza, Guillain-Barré, GWAS, Genetic Sequencing
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NOVOCART®3D for Treatment of Articular Cartilage of the Knee
NCT01957722
Recruiting
This study is to compare NOVOCART 3D relative to Microfracture for the treatment of knee cartilage defects. Efficacy will be evaluated by both pain and function. Safety will also be evaluated.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/01/2022
Locations: Va Eastern Colorado Health System, Denver, Colorado
Conditions: Articular Cartilage of the Femoral Condyle Between 2-6cm2
Register for Updates
ALT Routinely Recorded Remotely: A Comparator Study of Liver Function Tests Using the Tasso+ to Venipuncture.
NCT05259618
Recruiting
A direct comparison study of blood samples collected using the Tasso+ device and venous blood samples in patients with elevated alanine transaminase (ALT).
Gender:
All
Ages:
18 years and above
Trial Updated:
02/24/2022
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Elevated Alanine Transaminase (ALT)
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Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC
NCT03257033
Recruiting
The study is a multi-center, un-blinded, randomized control study of subjects with locally advanced pancreatic adenocarcinoma which is unresectable.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2022
Locations: Rocky Mountain Cancer Centers, Denver, Colorado
Conditions: Locally Advanced Pancreatic Cancer
Register for Updates
Performance of the Dexcom Continuous Glucose Monitoring (CGM) System in Pregnant Women With Diabetes Mellitus
NCT04905628
Recruiting
Performance of the Dexcom Continuous Glucose Monitoring (CGM) System in Pregnant Women With Diabetes Mellitus
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/17/2022
Locations: Barbara Davis Center for Childhood Diabetes, Aurora, Colorado
Conditions: Diabetes Mellitus
Register for Updates