Colorado is currently home to 1915 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL
NCT03509961
Recruiting
This study will evaluate the use of non- TBI (total body irradiation) conditioning for B-ALL patients with low risk of relapse as defined by absence of NGS-MRD (next generation sequencing minimal residual disease) before receiving a hematopoietic cell transplant (HCT). Patients diagnosed with B-ALL who are candidates for HCT will be screened by NGS-MRD on a test of bone marrow done before the HCT. Subjects who are pre-HCT NGS-MRD negative will be eligible to receive a non-TBI conditioning regime... Read More
Gender:
All
Ages:
Between 1 year and 25 years
Trial Updated:
08/20/2021
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: B-cell Acute Lymphoblastic Leukemia
Register for Updates
Effects of Aromatherapy on Patient Satisfaction With Surgical Abortion at Less Than 10 Weeks Gestation
NCT04969900
Recruiting
The investigators propose a single-site, double-blinded, placebo-controlled clinical trial of lavender aromatherapy versus placebo for patient satisfaction in adult women having a surgical abortion before 10 weeks and 0 days gestation. The investigators will evaluate whether lavender aromatherapy is an effective adjunct therapy for patient satisfaction during first trimester surgical abortion. The investigators will measure satisfaction using the Iowa Satisfaction with Anesthesia Scale (ISAS). T... Read More
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
08/17/2021
Locations: Comprehensive Women's Health Center, Denver, Colorado
Conditions: Surgical Abortion, Patient Satisfaction, Anesthesia, Pain
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Multi-Center Study to Evaluate the Efficacy and Safety of Sildenafil Cream (3.6%) in Premenopausal Patients With Female Sexual Arousal Disorder
NCT04948151
Recruiting
This study is looking to minimize side effects, while maintaining and potentially improving the therapeutic benefit to patients suffering from Female Sexual Arousal Disorder by providing a topical preparation of Sildenafil locally to the vulvar-vaginal tissue.
Gender:
Female
Ages:
21 years and above
Trial Updated:
06/24/2021
Locations: Downtown Women's Healthcare, Denver, Colorado
Conditions: Female Sexual Arousal Disorder
Register for Updates
Measuring Omalizumab Responses Using Real-world Evidence (MORRE) Study
NCT04724278
Recruiting
Develop new real-world evidence indicators of worsening and improving asthma. Scientists will measure (1) steps per day, (2) duration and intensity of exercise per day, (3) sleep duration and the number of awakenings per night using Fitbit activity trackers. Scientists will measure asthma symptoms using a once-monthly custom survey delivered to participant smartphones via Twilio. Scientists may measure rescue medication use and adherence to maintenance medications using digital inhaler devices.... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
06/21/2021
Locations: National Jewish Health, Denver, Colorado
Conditions: Asthma
Register for Updates
Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block
NCT04559425
Recruiting
Few studies are specifically designed to address health concerns that are already relevant during pregnancy. The consequence is a lack of evidence on best clinical practice. This includes mothers and their babies when pregnancy is complicated by an abnormally slow heart rate due to maternal antibody-mediated heart disease in the unborn baby (fetus). Since the late seventies, it has been possible to detect and monitor fetal disease by ultrasound images and to treat selected conditions with pharma... Read More
Gender:
Female
Ages:
Between 16 years and 50 years
Trial Updated:
06/10/2021
Locations: Children's Hospital Colorado, Denver, Colorado
Conditions: Heart Block Complete, Heart Block Second Degree
Register for Updates
Home Based Infusions for Ocrelizumab
NCT04650321
Recruiting
The goal is to assess the safety and effectiveness of home ocrelizumab infusion.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
06/08/2021
Locations: Amerita, Centennial, Colorado
Conditions: Multiple Sclerosis
Register for Updates
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
NCT04916210
Recruiting
The overall goal of the DISCOVERY study is to better understand what factors contribute to changes in cognitive (i.e., thinking and memory) abilities in patients who experienced a stroke. The purpose of the study is to help doctors identify patients at risk for dementia (decline in memory, thinking and other mental abilities that significantly affects daily functioning) after their stroke so that future treatments may be developed to improve outcomes in stroke patients. For this study, a "stroke... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2021
Locations: University of Colorado, Denver, Colorado
Conditions: Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Dementia, Vascular, Mild Cognitive Impairment, Vascular Cognitive Impairment
Register for Updates
Objective Measures of Nerve Integrity, Posture, Gait and Blood Flow, After Nerve Decompression
NCT01735903
Recruiting
The purpose of this study is to measure the effect of nerve decompression on the recovery of the treated nerves. To obtain objective data during surgery of the treated nerves' via electrical signals and muscle power when stimulated. Also, to monitor muscle strength, balance/gait and blood flow in the lower extremity before and after surgery.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
02/15/2021
Locations: Anderson Podiatry Center, Neuropathy Testing Center of Colorado, Fort Collins, Colorado
Conditions: Diabetic Peripheral Neuropathy
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An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT04718818
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Colorado Springs, Colorado
Conditions: Ulcerative Colitis
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Study to Evaluate the Benefit of RUCONEST in Improving Neurological Symptoms in Post COVID-19 Infection
NCT04705831
Recruiting
Randomized, Double Blind, Placebo Controlled, Proof-of-Concept Study to Evaluate the Benefit of RUCONEST in Improving Neurological Symptoms in Post-SARS-CoV-2 Infection.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
01/08/2021
Locations: IMMUNOe Research Centers, Centennial, Colorado
Conditions: Post-Viral Fatigue Syndrome, Post-Viral Disorder (Disorder), Covid19
Register for Updates
Evaluation of the Safety and Effectiveness of the Dexcom Glucose Monitoring (CGM) System
NCT04645641
Recruiting
Evaluation of the Safety and Effectiveness of the Dexcom Glucose Monitoring (CGM) System
Gender:
All
Ages:
2 years and above
Trial Updated:
11/25/2020
Locations: Barbara Davis Center, Aurora, Colorado
Conditions: Diabetes Mellitus
Register for Updates
Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)
NCT01088217
Recruiting
The purpose of this study is to investigate inherited genetic factors that play a role in the development of familial pulmonary fibrosis and to identify a group of genes that predispose individuals to develop pulmonary fibrosis. Finding the genes that cause pulmonary fibrosis is the first step at developing better methods for early diagnosis and improved treatment for pulmonary fibrosis. The overall hypothesis is that inherited genetic factors predispose individuals to develop pulmonary fibrosis... Read More
Gender:
All
Ages:
All
Trial Updated:
09/11/2020
Locations: University of Colorado Denver, Aurora, Colorado
Conditions: Idiopathic Pulmonary Fibrosis, Familial Pulmonary Fibrosis, Idiopathic Interstitial Pneumonia, Familial Interstitial Pneumonia
Register for Updates