There are currently 255 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Pennsylvania.
Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
NCT04123314
Recruiting
This open-label pilot study examines whether the hallucinogenic drug, psilocybin, given under supportive conditions, is safe and effective for depression in people with Mild Cognitive Impairment (MCI) or early Alzheimer's Disease (AD). This study will also assess whether psilocybin may improve quality of life in those individuals.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
08/14/2024
Locations: Behavioral Pharmacology Research Unit, Baltimore, Maryland
Conditions: Depressive Symptoms, Depression, Alzheimer Disease, Mild Cognitive Impairment
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Collaborative Care for Treatment of Depression and Anxiety
NCT06556589
Recruiting
The goal of this project is to evaluate the effectiveness of a collaborative care model for primary care patients at Kaiser Permanente Colorado (KPCO) with depression and/or anxiety. Collaborative care uses evidence-based short-term treatments delivered to patients over the phone. We will explore the use of cost-efficient automated processes for patient outreach and follow-up, such as care pools of patients and using patient portal messaging, risk-based results routing to providers, and electron... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2024
Locations: Kaiser Permanente Colorado, Aurora, Colorado
Conditions: Depression, Anxiety
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Evaluation of the PACE/PACENET BHL Clinical Program
NCT02463266
Recruiting
The SUpporting Seniors Receiving Treatment And INtervention (SUSTAIN) program is a telephone-based clinical service designed to help identify and manage behavioral health issues among PACE/PACENET enrollees. The purpose of the current project is to a) explore moderators of treatment response among beneficiaries in the SUSTAIN Clinical Program and b) to evaluate the sustained clinical effects of the program.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
08/12/2024
Locations: Department of Psychiatry (Center for Psychotherapy Research), University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Depression, Anxiety, Pain, Chronic
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Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression
NCT06002204
Recruiting
SHAKTI (from the Sanskrit word for "power") is a 5-year natural history, longitudinal, prospective study of a cohort of 6,000 participants that will help uncover the socio-demographic, lifestyle, clinical, psychological, and neurobiological factors that contribute to antidepressant treatment response (remission, recurrence, relapse and individual outcomes in depressive disorders) and resilience. As this is an exploratory study, we will assess a comprehensive panel of carefully selected participa... Read More
Gender:
ALL
Ages:
10 years and above
Trial Updated:
08/12/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Depression, Treatment Resistant Depression, Mood Disorders, Bipolar Disorder, Mental Disorders, Bipolar and Related Disorders
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A Computerized Depression Intervention in Veterans
NCT06217198
Recruiting
Depressive symptoms are common among Veterans and associated with significant impairment. Timely intervention has the potential to improve mental health outcomes and restore functioning. Interventions delivered through the internet can be completed remotely at any time, and thus minimize burden on Veterans, however the research examining their utility in Veterans is limited. This proposed project will examine Deprexis, a self-guided internet-delivered intervention, which targets depressive sympt... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/07/2024
Locations: Central Texas Veterans Health Care System Waco VA Medical Center, Waco, TX, Waco, Texas
Conditions: Depression
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Implementation of Collaborative Care for Depression in VA HIV Clinics
NCT05901272
Recruiting
HIV Translating Initiatives for Depression into Effective Solutions (HITIDES) is a team-based service to manage depression in Veterans Living with HIV (VLWH). This service is more effective for managing depression than the care VLWH usually receive and saves resources. HITIDES is also liked by HIV care providers and VLWH. Despite this, no VA clinics currently offer this service. This study examines two approaches to engage clinics with HITIDES, the resulting effects on VLWH, and the costs of the... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/02/2024
Locations: Central Arkansas Veterans Healthcare System , Little Rock, AR, Little Rock, Arkansas
Conditions: HIV, Depression
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Reward Processing and Depressive Subtypes: Identifying Neural Biotypes
NCT06080646
Recruiting
Deficits in motivation and pleasure are common in depression, and thought to be caused by alterations in the ways in which the brain anticipates, evaluates, and adaptively uses reward-related information. However, reward processing is a complex, multi-circuit phenomenon, and the precise neural mechanisms that contribute to the absence or reduction of pleasure and motivation are not well understood. Variation in the clinical presentation of depression has long been a rule rather than an exception... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/31/2024
Locations: San Francisco Healthcare System, San Francisco, California
Conditions: Depression, Depressive Disorder, Major Depressive Disorder, Major Depressive Episode, Depressive Symptoms, Anhedonia
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Accelerated rTMS for Substance Use Disorder and Depression
NCT06424184
Recruiting
This study is a small open-label feasibility trial of an accelerated course of repetitive transcranial magnetic stimulation (rTMS) for individuals with depression and stimulant use disorder \[including methamphetamine or cocaine use disorder (MUD/CUD)\].
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/24/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Stimulant Use, Depression
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Project 2: Optimizing Engagement and Outcomes in STAND Digital Therapy
NCT05908565
Recruiting
The goal is to optimize peer coaching in order to optimize engagement and outcomes in digital therapy. The unmet mental health needs of community college students are staggering and a growing body of research demonstrates that therapy provided digitally with the assistance of trained community members without advanced degrees in mental health is an effective and scalable way to address these needs. Despite being effective for improving symptoms and functioning in those who engage in it, uptake a... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
07/23/2024
Locations: East Los Angeles College, Los Angeles, California
Conditions: Depression, Anxiety
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S.T.A.N.D. Alacrity Center Signature Project
NCT05591937
Recruiting
The purpose of this study is to evaluate clinical decision-making algorithms for (a) triaging to level of care and (b) adapting level of care in a low income, highly diverse sample of community college students at East Los Angeles College (ELAC). The target enrollment is 200 participants per year, for five years (N=1000). Participants are between the ages of 18 and 40 years and will be randomized into either symptom severity decision-making (SSD) or data-driven decision-making (DDD). Participan... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
07/23/2024
Locations: East Los Angeles College, Los Angeles, California
Conditions: Depression, Anxiety
Register for Updates
Healthcare Providers as Trusted Messengers to Increase Receipt of Tax Credits Among Low-income Families
NCT05612685
Recruiting
The purpose of this study is to pilot test the feasibility, acceptability, and preliminary efficacy of healthcare provider referrals to a tax filing app within parent-child health programs to test whether such referrals can increase receipt of tax credits among low-income parents. The study will use a single-group, pre/post test design with a sample of approximately 100 women who have a child under 6 years of age. Participants will be recruited from parental-child health programs and clinics in... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
07/23/2024
Locations: UCLA School of Nursing, Los Angeles, California
Conditions: Depression, Child Development, Stress, Physical Illness, Health Care Utilization
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To Improve Depressive Symptoms Using a Web-App
NCT05405803
Recruiting
This study is being done to answer a question on whether a Web App-based Lifestyle Physical Activity Promotion Program is effective in improving depressive symptom experience of midlife Korean American women (WPAPP-K).
Gender:
FEMALE
Ages:
Between 40 years and 60 years
Trial Updated:
07/17/2024
Locations: The University of Texas at Austin, Austin, Texas
Conditions: Depression
Register for Updates