There are currently 269 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Texas.
Digital CBT for Insomnia and Depression
NCT05456607
Recruiting
This study has two primary objectives, each of which addresses critical clinical and research gaps for individuals who have co-occurring insomnia and depression. The first objective is to address whether sequential treatment of insomnia and depression is superior to a single treatment for either depression or for insomnia, and if so, which treatment sequence is optimal. The second objective is to determine if there are heterogeneity of treatment effects; that is, variation in which interventions... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: University of Rochester Sleep Research Laboratory, Rochester, New York
Conditions: Depression, Insomnia
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Internet Based Psychological Support
NCT02726061
Recruiting
The investigators have developed interactive, multimedia-intensive, computer-based treatment programs that include depression (Problem-Solving Therapy), stress management, and conflict management. Together the three modules are called PATH. The problem-solving module is based on an evidence-based psychotherapy called Problem-Solving Therapy in which depressed patients identify problems in their lives and work through a structured format for solving these problems. We have subjected the problem-... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Depression, Stress, Conflict Resolution
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Behavioral Activation-Rehabilitation to Improve Depressive Symptoms & Physical Function After Acute Respiratory Failure
NCT03431493
Recruiting
More and more people are surviving after receiving life support for respiratory failure in the intensive care unit, but these patients often experience problems with depression and physical functioning that lead to reduced quality of life. There is a lack of treatment for these patients, with past research suggesting that treatment may be more successful if mental and physical health are addressed at the same time. This research evaluates whether a therapy delivered via telephone and home visits... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
05/10/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Respiratory Insufficiency, Depression, Rehabilitation, Critical Care
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Virtual Reality-Reward Training for Anhedonia
NCT05342077
Recruiting
The purpose of this study is to compare the effects of Virtual Reality-Reward Training (VR-RT) with an active control condition, Virtual Reality-Memory Training (VR-MT), on positive affect and other clinical symptoms. VR-Reward Training is a novel intervention aimed at enhancing savoring of positive experiences among individuals with depression and low positive affect through guided imaginal recounting following immersion in positive VR experiences. Target enrollment is 80 male and female part... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2024
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Positive Affect, Depression
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Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans
NCT05094297
Recruiting
This research study is being done to investigate if the GH Method exercise program positively affects body composition, improves physical abilities and can improve the overall sense of wellbeing (e.g. depression, PTSD, etc.) in U.S. Veterans. Subjects will be asked to complete 94 total visits (four (4) study testing visits and 90 exercise visits). Enrolled subjects will be tested for fitness, strength, and health risk factors at UIC 4 times and will complete 90 exercise training visits at the GH... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Chronic Pain, Acute Pain, Fatigue, Depression
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Cannabidiol and Older Adult Cannabis Users
NCT06290063
Recruiting
Cannabis use increased 10 fold among adults over the age of 65 between 2014 and 2016 but very little data exists on the extent of their harmful effects on health and behavior. The overarching goal of this project is to test a novel harm reduction strategy in which older individuals who seek to use cannabis for pain, anxiety or mood problems (depression/anxiety) will be randomly assigned to one of three conditions in an 8 week randomized controlled trial: hemp-derived CBD+THC, hemp-derived CBD-TH... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
05/06/2024
Locations: University of Colorado at Boulder, Boulder, Colorado
Conditions: Sleep, Anxiety, Depression, Pain
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Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality
NCT05925322
Recruiting
The investigators hypothesized that during the 9-week course of Engage & Connect treatment there will be an increase in brain functions of the Positive Valence System which in turn will lead to reduction in suicidality.
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
05/06/2024
Locations: Weill Cornell Medicine, New York, New York
Conditions: Depression, Suicidal Ideation, Major Depressive Disorder, Depressive Disorder
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Enhancing Purpose and Well-Being Through a Volunteering Experience Connecting Veterans With English Language Learners
NCT06324383
Recruiting
The goal of this study is to refine and test a strategy for engaging Veterans with symptoms of depression, anxiety, and/or PTSD (Post Traumatic Stress Disorder) as volunteers to help English language learners (ELLs) improve their speaking skills via structured conversations using videoconferencing.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: Center for Clinical Management Research (CCMR), North Campus Research Complex, Ann Arbor, Michigan
Conditions: Depression, Anxiety, Post Traumatic Stress Disorder
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Personalized Depression Treatment Supported by Mobile Sensor Analytics
NCT06292221
Recruiting
The current best practice guidelines for treating depression call for close monitoring of patients, and periodically adjusting treatment as needed. This present study seeks to develop and investigate an innovative digital system, DepWatch, that leverages mobile health technologies and machine learning tools to provide clinicians objective, accurate, and timely assessment of depression symptoms to assist with their clinical decision making process. Specifically, DepWatch collects sensory data pas... Read More
Gender:
All
Ages:
All
Trial Updated:
05/02/2024
Locations: University of Connecticut Health Center, Farmington, Connecticut
Conditions: Depression
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Depression Screening in Black Churches
NCT04524767
Recruiting
The overall aim of this study is to employ Community Health Workers (CHWs) to screen for depression in 30 Black churches and compare the effectiveness of Screening, Brief Intervention, and Referral to Treatment (SBIRT) (Intervention arm) to Referral As Usual (Control arm) on treatment engagement for depression. The investigators will assess patient-level outcomes (Mental-Health Related Quality of Life and depressive symptoms) at 3- and 6-months post-screening and conduct a mixed-methods process... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2024
Locations: Columbia University Irving Medical Center Center, New York, New York
Conditions: Depression
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Acceptance and Commitment Therapy for Depressed People With Spinal Cord Injuries
NCT06233656
Recruiting
Living with spinal cord injury (SCI) can have a significant negative impact on an individual's mental health and restrict participation in personally valued activities and roles. Acceptance and commitment therapy (ACT) is an evidence-based approach that can lessen symptoms of mental health disorders (e.g., depressive symptoms) and improve quality of life through mindfulness and acceptance processes and behavior change processes for valued living. Evidence for ACT for individuals living with SCI,... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Depression, Spinal Cord Injuries
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REstoring Mental Health After SARS-CoV-2 Through commUnity-based Psychological Services in New York City
NCT04913766
Recruiting
The goal is to improve mental health of minority and other vulnerable populations disproportionately affected by SARS-CoV-2. The study will evaluate the impact of mental health services on SARS-CoV-2 mitigation strategies such as prevention behaviors, receiving vaccinations, and safe healthcare utilization. Successful completion of this study will contribute to the National Institute of Mental Health Strategic Plan employing implementation science to maximize the public health impact of research... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: New School, New York, New York
Conditions: Depression, Anxiety, Psychological Distress, PTSD
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