There are currently 254 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Pennsylvania.
Internet Based Psychological Support
NCT02726061
Recruiting
The investigators have developed interactive, multimedia-intensive, computer-based treatment programs that include depression (Problem-Solving Therapy), stress management, and conflict management. Together the three modules are called PATH. The problem-solving module is based on an evidence-based psychotherapy called Problem-Solving Therapy in which depressed patients identify problems in their lives and work through a structured format for solving these problems. We have subjected the problem-... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Depression, Stress, Conflict Resolution
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Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans
NCT05094297
Recruiting
This research study is being done to investigate if the GH Method exercise program positively affects body composition, improves physical abilities and can improve the overall sense of wellbeing (e.g. depression, PTSD, etc.) in U.S. Veterans. Subjects will be asked to complete 94 total visits (four (4) study testing visits and 90 exercise visits). Enrolled subjects will be tested for fitness, strength, and health risk factors at UIC 4 times and will complete 90 exercise training visits at the GH... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Chronic Pain, Acute Pain, Fatigue, Depression
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Cannabidiol and Older Adult Cannabis Users
NCT06290063
Recruiting
Cannabis use increased 10 fold among adults over the age of 65 between 2014 and 2016 but very little data exists on the extent of their harmful effects on health and behavior. The overarching goal of this project is to test a novel harm reduction strategy in which older individuals who seek to use cannabis for pain, anxiety or mood problems (depression/anxiety) will be randomly assigned to one of three conditions in an 8 week randomized controlled trial: hemp-derived CBD+THC, hemp-derived CBD-TH... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/06/2024
Locations: University of Colorado at Boulder, Boulder, Colorado
Conditions: Sleep, Anxiety, Depression, Pain
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Enhancing Purpose and Well-Being Through a Volunteering Experience Connecting Veterans With English Language Learners
NCT06324383
Recruiting
The goal of this study is to refine and test a strategy for engaging Veterans with symptoms of depression, anxiety, and/or PTSD (Post Traumatic Stress Disorder) as volunteers to help English language learners (ELLs) improve their speaking skills via structured conversations using videoconferencing.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: Center for Clinical Management Research (CCMR), North Campus Research Complex, Ann Arbor, Michigan
Conditions: Depression, Anxiety, Post Traumatic Stress Disorder
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Personalized Depression Treatment Supported by Mobile Sensor Analytics
NCT06292221
Recruiting
The current best practice guidelines for treating depression call for close monitoring of patients, and periodically adjusting treatment as needed. This present study seeks to develop and investigate an innovative digital system, DepWatch, that leverages mobile health technologies and machine learning tools to provide clinicians objective, accurate, and timely assessment of depression symptoms to assist with their clinical decision making process. Specifically, DepWatch collects sensory data pas... Read More
Gender:
ALL
Ages:
All
Trial Updated:
05/02/2024
Locations: University of Connecticut Health Center, Farmington, Connecticut
Conditions: Depression
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Depression Screening in Black Churches
NCT04524767
Recruiting
The overall aim of this study is to employ Community Health Workers (CHWs) to screen for depression in 30 Black churches and compare the effectiveness of Screening, Brief Intervention, and Referral to Treatment (SBIRT) (Intervention arm) to Referral As Usual (Control arm) on treatment engagement for depression. The investigators will assess patient-level outcomes (Mental-Health Related Quality of Life and depressive symptoms) at 3- and 6-months post-screening and conduct a mixed-methods process... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/01/2024
Locations: Columbia University Irving Medical Center Center, New York, New York
Conditions: Depression
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REstoring Mental Health After SARS-CoV-2 Through commUnity-based Psychological Services in New York City
NCT04913766
Recruiting
The goal is to improve mental health of minority and other vulnerable populations disproportionately affected by SARS-CoV-2. The study will evaluate the impact of mental health services on SARS-CoV-2 mitigation strategies such as prevention behaviors, receiving vaccinations, and safe healthcare utilization. Successful completion of this study will contribute to the National Institute of Mental Health Strategic Plan employing implementation science to maximize the public health impact of research... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: New School, New York, New York
Conditions: Depression, Anxiety, Psychological Distress, PTSD
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Reaching Out to Distressed Medical Residents, Fellows and Faculty
NCT02010866
Recruiting
The purpose of this study is to study whether distressed medical residents, fellows, and faculty health professionals benefit from completing online an anonymous and interactive screening of stress, depression, substance use, and suicidal thoughts. The screening and ability to interact online with a clinician anonymously are hypothesized to increase willingness to come for counseling in person. Suicide risk factors are expected to be lower once the distressed medical trainee or faculty member re... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/27/2024
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Depression, Suicide
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Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
NCT06374277
Recruiting
Socioeconomically disadvantaged populations with multiple chronic conditions have high rates of nonadherence to essential chronic disease medications after hospital discharge. Medication nonadherence after hospital discharge is significantly associated with increased mortality and higher rates of readmissions and costs among these patients. Major patient-reported barriers to essential medication use after hospital discharge among low-income individuals are related to social determinants of healt... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: University of Tennessee Medical Center, Knoxville, Tennessee +1 locations
Conditions: Diabetes, Hypertension, High Cholesterol/Hyperlipidemia, Coronary Artery Disease, Congestive Heart Failure, Chronic Lung Disease, Chronic Kidney Diseases, Arrythmia, Stroke, Depression, Anxiety, Pulmonary Embolism, Heart Attack
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An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression
NCT05466851
Recruiting
This research study is studying how thoughts, feelings, surroundings, and individual biology may contribute to why and how people experience anxiety or depression. We are trying to find out the wide variety of reasons that people may experience anxiety or depression, and why different people are helped by different forms of treatment. We are trying to determine why people stay in treatment, and what factors contribute to a positive or negative response to treatment. These reasons may be due to... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/15/2024
Locations: Singula Institute, 353 Lexington Avenue (Room 600), New York, New York
Conditions: Depression, Anxiety Disorders, Stress Related Disorder
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M-O-M-S on the Bayou: Implementation of an Intervention for Mental Health in Pregnancy
NCT05838404
Recruiting
Disasters have negative effects in the short term (physical trauma, adverse environmental exposures, and unstable housing) and the long term (relocation, changes in family functioning, and negative economic effects), which interact with social determinants to worsen health among the most vulnerable women, infants, and communities. Trauma and severe stress are directly linked to pregnancy complications, and raise blood pressure during pregnancy, alter stress hormones, and increase vulnerability t... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/09/2024
Locations: Tulane University, New Orleans, Louisiana
Conditions: Anxiety, Depression
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Buspirone and Melatonin for Depression Following Traumatic Brain Injury
NCT04400266
Recruiting
Traumatic brain injuries (TBIs) are common. Post-TBI depression is associated with anxiety, aggression, fatigue, distractibility, anger, irritability, and rumination. The current research group conducted a pilot clinical trial, which investigated the novel treatment combination of buspirone and melatonin (B+MEL) in outpatients with clinical depression. Compared to placebo, B+MEL was associated with a significant improvement in depressive symptoms. Depression following TBI may be different from c... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
04/09/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations
Conditions: Depression, Brain Injuries, Traumatic
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