There are currently 281 active clinical trials seeking participants for Depression research studies. The states with the highest number of trials for Depression participants are California, New York, Florida and Pennsylvania.
Microbiome, Anxiety and Cognitive Orientation Study
NCT05388630
Recruiting
Mounting evidence shows that the gut microbiome plays an important role in communication within the gut-brain axis. However, the relationship between gut microbiota and their influence on anxiety is still not fully understood. Recent studies on mice found a specific microbe-produced molecule, 4-ethylphenyl sulfate (4EPS), can induce anxious behavior. 4EPS is produced by gut microbes in mice and humans. Research suggests higher 4EPS levels may strongly be associated with anxiety levels. However,... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/12/2022
Locations: Endominance Inc., Irvine, California
Conditions: Anxiety, Microbiome, Mood Disorders, Neurodegeneration, Depression
Register for Updates
Study on Allopregnanolone and Depression in Perimenopausal Women
NCT05329779
Recruiting
This study aims to identify how the progesterone metabolite allopregnanolone affects behavior and neurobiology that may underlie perimenopausal depression.
Gender:
Female
Ages:
Between 40 years and 60 years
Trial Updated:
11/08/2022
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Depression
Register for Updates
Ketamine and Epigenetic Aging
NCT05294835
Recruiting
This is a prospective, clinical pilot study (n=20) to evaluate the impact of a ketamine treatment for Major Depressive Disorder (MDD) or Post Traumatic Stress Disorder (PTSD) on epigenetic aging by the TruAge epigenetic age laboratory test.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
09/07/2022
Locations: Wild Health, Lexington, Kentucky
Conditions: Depression, Post Traumatic Stress Disorder
Register for Updates
Biofeedback for Psoriasis
NCT05506644
Recruiting
We are conducting a proof-of-concept trial to study the impact of HRV-biofeedback, a mind-body technique designed to improve stress resilience, on the quality of life, mood, and clinical skin severity of patients with psoriasis.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/16/2022
Locations: Bastyr University Clinic, San Diego, California
Conditions: Psoriasis, Psoriasis Vulgaris, Psychophysiological Disorder, Anxiety, Depression, Psychological Stress, Physiological Stress, Quality of Life, Skin Disorder, Skin Diseases
Register for Updates
Heartfulness Meditation to Improve Resilience Among Health Care Students: A 90 Day Program
NCT04790162
Recruiting
This investigation will examine the feasibility of delivery and effect on resilience, depression and anxiety of a 90-day Heartfulness Practice delivered virtually for health care students. It is hypothesized that by providing this program on-line, students will be able to attend easily and complete the sessions. It is also hypothesized that those students who participate in the meditation program will increase resilience.
Gender:
All
Ages:
Between 20 years and 70 years
Trial Updated:
08/12/2022
Locations: University of Colorado Anschutz, Aurora, Colorado
Conditions: Mental Health Wellness 1, Stress, Psychological, Depression, Anxiety
Register for Updates
Lay-Delivered Behavioral Activation in Senior Centers
NCT04621877
Recruiting
In response to large numbers of senior center clients who suffer untreated depression and the dearth of geriatric mental health providers, the investigators have simplified Behavioral Activation to be delivered by lay volunteers ("Do More, Feel Better"; DMFB). The focus of Behavioral Activation is to guide clients to reengage in daily pleasant and rewarding activities, and reduce depressive symptoms. If the investigators can show that the lay delivery model has positive impact in comparison to M... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
07/25/2022
Locations: Brandon Senior Center, Brandon, Florida +11 locations
Conditions: Depression
Register for Updates
Integrating a Suite of Mental Health Apps for Depression in a Healthcare Setting
NCT05274620
Recruiting
The purpose of this study is to evaluate the implementation of IntelliCare as a frontline intervention within health care settings.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/18/2022
Locations: Northwestern Medicine Dept of Psychiatry, Chicago, Illinois +1 locations
Conditions: Depression, Anxiety
Register for Updates
PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents
NCT04290754
Recruiting
PATH (Promoting AdolescenT Health) 2 Purpose is a two-arm comparative effectiveness research trial to that will evaluate the ability of the interventions, Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT) and Teens Achieving Mastery over Stress (TEAMS), to intervene early to prevent depressive illness and potentially other common mental health disorders. Using cluster randomization, 564 participants eligible for the study will be offered one of two diff... Read More
Gender:
All
Ages:
Between 13 years and 19 years
Trial Updated:
06/28/2022
Locations: UI Health, Chicago, Illinois
Conditions: Depression
Register for Updates
Engaging Pacific Islanders in Mental Health Treatment
NCT04890977
Recruiting
This study will create and pilot test a culturally grounded intervention (Talking Story) to increase mental health treatment seeking among Pacific Islanders with mental disorders (e.g., major depressive disorder, generalized anxiety disorder).
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2022
Locations: UC Riverside, Riverside, California
Conditions: Depression, Anxiety Disorders
Register for Updates
Outcomes Mandate National Integration With Cannabis as Medicine
NCT03944447
Recruiting
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
Gender:
All
Ages:
7 years and above
Trial Updated:
05/29/2022
Locations: OMNI Medical Services, Boca Raton, Florida +16 locations
Conditions: Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma, Fibromyalgia, Seizures, Hepatitis C, Cancer, Crohn Disease, HIV/AIDS, Multiple Sclerosis, Traumatic Brain Injury, Sickle Cell Disease, Post Traumatic Stress Disorder, Tourette Syndrome, Ulcerative Colitis, Glaucoma, Epilepsy, Inflammatory Bowel Diseases, Parkinson Disease, Amyotrophic Lateral Sclerosis, Chronic Traumatic Encephalopathy, Anxiety, Depression, Insomnia, Autism, Opioid-use Disorder, Bipolar Disorder, Covid19, SARS-CoV Infection, COVID-19, Corona Virus Infection, Coronavirus
Register for Updates
Reducing Transphobia Among Adolescents Through a Brief Video Intervention
NCT04969003
Recruiting
The purposes of this new study are to test among adolescent viewers the utility of brief video-based interventions to: reduce transphobia; reduce depression-related stigma and increase likelihood of treatment-seeking; and examine the role of viewer's sex (male / female / non-binary), race (Black vs non-Black), and sexual orientation (straight vs LGBQ) as independent factors on the outcomes of interest.
Gender:
All
Ages:
Between 14 years and 18 years
Trial Updated:
04/28/2022
Locations: Yale Child Center, New Haven, Connecticut +1 locations
Conditions: Transgenderism, Depression
Register for Updates
Behavioral Activation Plus Savoring for University Students
NCT05234476
Recruiting
The current investigation aims to examine whether a brief, two-session, virtual behavioral activation plus savoring intervention will increase daily positive emotion in university students.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/15/2022
Locations: Southern Methodist University, Dallas, Texas
Conditions: Mood, Anhedonia, Depression
Register for Updates