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California Paid Clinical Trials
A listing of 5602 clinical trials in California actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
2941 - 2952 of 5602
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California is currently home to 5602 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Featured Trial
Healthy Participants Needed (Colonoscopy + Cancer Screening)
Recruiting
Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.
Conditions:
Healthy
Healthy Volunteers
Healthy Subjects
Healthy Volunteer
Healthy Participants
Featured Trial
Buy Retatrutide Online Through Celia
Recruiting
Retatrutide (formerly M25) is an investigational peptide being studied for its potential in supporting weight management and metabolic health. It acts on GLP-1, GIP, and glucagon receptors to influence appetite, energy regulation, and fat metabolism.
Conditions:
Healthy
Featured Offer
Lose 20% of Body Weight With GLP-1's
Recruiting
Policy Lab has partnered with OnlineSemaglutide.org to offer trusted access to tirzepatide and other GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.
Semaglutide and Tirzepatide are advanced GLP-1 medications designed to support weight management and metabolic health. They work by targeting GLP-1 receptors in the body, helping regulate appetite, improve blood sugar control, and support sustainable weight loss (up to 22% of body weight).
Get $50 off your first order using promo code: policy-lab-50
Semaglutide and Tirzepatide are advanced GLP-1 medications designed to support weight management and metabolic health. They work by targeting GLP-1 receptors in the body, helping regulate appetite, improve blood sugar control, and support sustainable weight loss (up to 22% of body weight).
Get $50 off your first order using promo code: policy-lab-50
Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Featured Trial
Depression Clinical Trial
Recruiting
Join us in researching a potential investigational treatment for Depression. Reimbursement for study-related expenses may be available to you.
Qualifying participants:
•Are between 18-65
•Have been experiencing a major depressive episode for at least a month
Qualifying participants:
•Are between 18-65
•Have been experiencing a major depressive episode for at least a month
Conditions:
Depression
Major Depressive Disorder
Depressive Disorder
Depressive Symptoms
Depressive Disorder
Featured Trial
Stroke Clinical Study
Recruiting
A clinical study for people that suffer with Stroke
Conditions:
Stroke
Enhancing Digitally Delivered Diabetes Education With Real-Time CGM
Recruiting
The current research study will add continuous glucose monitoring devices to the evidence-based text messaging diabetes education program for patients with type 2 diabetes for 6 months. Results on the effectiveness of this intervention will be compared for non-insulin using patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: Scripps Whittier Diabetes Institute, San Diego, California
Conditions: Diabetes Type 2
Safety, Tolerability, and Distribution of Laquinimod Eye Drops : The LION Study
Recruiting
The LION Study is a prospective, single-center phase 1 clinical trial to evaluate the safety, tolerability, and distribution of Laquinimod administered as topical eye drops for two weeks in human participants.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: Spencer Center for Vision Research at the Byers Eye Institute, Palo Alto, California
Conditions: Uveitis, Inflammation
Evaluation of the Novel Silq ClearTract Catheter in Patients With Chronic Urinary Retention
Recruiting
To assess the ability of the Silq ClearTract™ 100% Silicone 2-Way Foley Catheter to reduce catheter associated complications in subjects that require a long-term indwelling Foley catheter when compared to other commercially available Foley catheters.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: Rancho Los Amigos National Rehabilitation Center, Downey, California
Conditions: Catheter Infection, Catheter Blockage, Catheter Related Complication, Catheter Calcification
buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest
Recruiting
RESTORE is a randomized clinical trial investigating the safety and feasibility of using EEG treatment targets (burst suppression vs. seizure suppression) for post-cardiac arrest refractory status epilepticus treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: Zuckerberg San Francisco General Hospital, San Francisco, California
Conditions: Hypoxia-Ischemia, Brain, Heart Arrest, Status Epilepticus, Refractory Status Epilepticus, Seizures, Anoxic-Ischemic Encephalopathy, Anoxia-Ischemia, Cerebral
Innovations in Genicular Outcomes Registry
Recruiting
The registry will capture prospective data on patients receiving pain management for chronic pain due to knee osteoarthritis (OA) or pain optimization for knee arthroplasty due to knee OA. The OA pain therapies may include cryo nerve block, radiofrequency ablation (RFA), intra-articular (IA) corticosteroids, viscosupplementation, opioids, and others (e.g., non-steroidal anti-inflammatory drugs \[NSAIDs\]).
Gender:
ALL
Ages:
All
Trial Updated:
05/12/2025
Locations: Orthopedic Education and Research Institute of So Ca (Hoag), Irvine, California
Conditions: Knee Osteoarthritis
SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer
Recruiting
This study is being done to answer the following question:
Is the chance of cancer spreading or returning the same if radiotherapy to the neck is guided, by using a special imaging study called lymph node mapping (lymphatic mapping) Single Photon Emission Computed Tomography (SPECT-CT), compared to the usual treatment when radiotherapy is given to both sides of the neck?
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: City of Hope Comprehensive Cancer Center, Duarte, California
Conditions: Oropharyngeal Cancer
A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer Survivors
Recruiting
This clinical trial evaluates a high intensity electronic health (eHealth) intervention program for reducing learning disparities in children with cancer. Most children with leukemia and lymphoblastic lymphoma can be cured due to advancements in diagnosis and treatment. However, because treatments for these conditions target the central nervous system, these children are at increased risk for developing neurocognitive late effects (problems with attention, thinking, learning, and remembering). F... Read More
Gender:
ALL
Ages:
6 years and above
Trial Updated:
05/12/2025
Locations: City of Hope Medical Center, Duarte, California
Conditions: Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Lymphoblastic Lymphoma
Ultrafiltration Versus IV Diuretics in Worsening Heart Failure
Recruiting
The REVERSE-HF study is a randomized controlled trial to evaluate clinical outcomes of adjustable ultrafiltration with the Aquadex System as compared to adjustable IV loop diuretics in patients with worsening heart failure (HF) and fluid overload.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: MemorialCare, Long Beach Medical Center, Long Beach, California
Conditions: Heart Failure (for Example, Fluid Overload), Heart Failure, Fluid Overload
Diagnostic and Prognostic Biomarkers for High-impact Chronic Pain: Development and Validation
Recruiting
To identify diagnostic and prognostic biomarker signatures of recovery versus having persisting high-impact chronic pain and functional disability in adults with Chronic Musculoskeletal Pain.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/12/2025
Locations: Stanford University, Palo Alto, California
Conditions: Chronic Musculoskeletal Pain, Pain, Pain, Chronic, Joint Pain
Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD
Recruiting
The aim of this study is to evaluate DCR-PHXC in participants with PH1 and severe renal impairment, with or without dialysis.
Gender:
ALL
Ages:
All
Trial Updated:
05/12/2025
Locations: Clinical Trial Site, San Francisco, California
Conditions: End Stage Renal Disease, Primary Hyperoxaluria Type 1
The Role of Virtual Reality During Regional Anesthesia
Recruiting
In this study, we will analyze the role of virtual reality in acute pain and anxiety management for regional anesthesia in pre-operative patients at Cedars-Sinai Medical Center.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
05/12/2025
Locations: Cedars Sinai Medical Center, Los Angeles, California
Conditions: Anxiety, Pain
Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy
Recruiting
This phase II trial studies how well atezolizumab works alone or in combination with etrumadenant or tocilizumab in treating men with localized prostate cancer before radical prostatectomy. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Androgens can cause the growth of prostate cancer cells. IL-6 is expressed by prostate cancer and within the tumor microenv... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: University of California, San Francisco, San Francisco, California
2941 - 2952 of 5602
Kaiser Permanente houses over 6,000 physicians in southern California and it is also one of the largest research centers on the state. On its clinical trial division, Kaiser Permanente conducts clinical trials of almost every specialty funded by pharmaceutical companies, government, and foundations.
The Cedars-Sinai Medical Center located in Los Angeles is one of the largest research centers owned and operated by a private hospital in the United States. Focusing on biomedical, cancer, and heart research among other specialties, you can find almost any type of clinical trials for both health and non-healthy volunteers at the research division of Cedar-Sinai Medical Center.
There are around 100,000 clinical trials happening every year across the United States about almost every condition out there. While most clinical trials are testing drugs or medical devices there are also many behavioral and observational trials going on at any point in time. Many paid research studies are held at these California locations.
Clinical trials are incredibly important for making new medical and scientific discoveries, finding new and better methods for diagnosing medical conditions early, testing new interventions, and even developing safer and more effective surgical procedures.
In order for all these discoveries to me made available to the general population they need to go through years of rigorous testing both in healthy and non-healthy volunteers. During those years, medical professionals follow a protocol that has been previously approved by the FDA or other regulatory agency to test the effectiveness and safety of their discovery.
Other people choose to participate in a clinical trial because they feel it is a good way to contribute to the advancement of medical knowledge and that their participation can help many people in the future. The following lists of trials are broken down by condition, and to find a specific clinical trial in your area click through to clinicaltrials.gov.
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