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California Paid Clinical Trials
A listing of 5590 clinical trials in California actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
2953 - 2964 of 5590
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California is currently home to 5590 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Offer
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Recruiting
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As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Hyperpolarized Pyruvate (13C) MR Imaging in Monitoring Patients with Prostate Cancer on Active Surveillance
Recruiting
This phase II trial studies the side how well hyperpolarized carbon C 13 pyruvate (HP C-13 pyruvate) magnetic resonance imaging (MRI) works in monitoring patients with prostate cancer on active surveillance who have not received treatment. Diagnostic procedures, such as MRI, may help visualize HP C-13 pyruvate uptake and breakdown in tumor cells.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: Prostate Adenocarcinoma, Prostate Cancer
Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery
Recruiting
Apply CT angiography, CT perfusion imaging and advanced image processing techniques to improve revascularization decision-making and surgical strategies in patients undergoing coronary artery bypass graft surgery.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
03/25/2025
Locations: Palo Alto Veterans Affaird Healthcare System, Palo Alto, California
Conditions: CAD, Atheroscleroses, Coronary, Computed Tomography, Coronary Artery Bypass
U3-1402 in Metastatic or Unresectable Non-Small Cell Lung Cancer
Recruiting
This study was designed to evaluate safety and antitumor activity of HER3-DXd in two parts: Dose Escalation and Dose Expansion.
In Dose Escalation, HER3-DXd was evaluated in participants with metastatic or unresectable NSCLC with epidermal growth factor receptor (EGFR) activating mutation after disease progression during/after EGFR tyrosine kinase inhibitor (TKI) therapy.
In Dose Expansion, HER3-DXd will be evaluated in participants with metastatic or unresectable NSCLC with EGFR activating mu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: City of Hope, Duarte, California
Conditions: Non-Small Cell Lung Cancer (NSCLC)
A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion
Recruiting
The purpose of this research is to evaluate and validate the performance of non-invasive imaging modalities for assessment of skin. A pressure cuff occlusion will be used to stimulate blood flow dynamic that these instruments are designed to sense. The researcher currently plan to assess only basic feasibility of the imaging instruments.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Beckman Laser Institute and Medical Clinic, Irvine, California
Conditions: Abnormal Vascular Flow
Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential
Recruiting
According to the National Burn Repository 2007, the most common type of burn injury is a partial thickness burns. The current standard of care for partial thickness burns is two weeks of topical therapy and wound care. Burns that do not heal within two weeks undergo surgical excision and skin grafting.
Gender:
ALL
Ages:
1 minute and above
Trial Updated:
03/25/2025
Locations: UCIMC, Orange, California
Conditions: Skin Burn Multiple
Evaluation of RBS2418 in Patients with Advanced, Metastatic, and Progressive Colorectal Cancer
Recruiting
RBS2418 is a specific immune modulator that works through the inhibition of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) and is designed to lead to anti-tumor immunity by protecting endogenous 2'-3'-cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) from hydrolysis and leading to the activation of antigen-presenting cells followed by T cell activation. The hypothesis is that RBS2418 versus placebo will be generally safe, well-tolerated, immunogenic, and will lead to ant... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Metastatic Colorectal Cancer, Advanced Colorectal Cancer
Music, Social Attention, and Dementia
Recruiting
This is an exploratory mixed-methods control-treatment study to evaluate if participation in rhythmic musical activities improves social attention and connectedness in individuals living with mild to moderate bvFTD and AD, and their caregivers. Secondary objectives include evaluating the potential relationships between brain networks associated with rhythm production, social attention, and connectedness in these populations.
Gender:
ALL
Ages:
Between 55 years and 89 years
Trial Updated:
03/24/2025
Locations: Sandler Neurosciences Center, San Francisco, California
Conditions: Frontotemporal Dementia, Alzheimer Disease
An Ophthalmic Safety Study in Patients With Breast Cancer
Recruiting
To assess ophthalmic health in parallel cohorts of patients with breast cancer
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
03/24/2025
Locations: Research Site, La Jolla, California
Conditions: Ophthalmic Safety in Patients With Breast Cancer
Single-Center Eval of Clinical & Radiological Benefit AHCC in Combo W/ SOC Tx for HPV+ Pts W/ HNSCC
Recruiting
This is a phase 2, single-arm, open-label clinical trial determining safety and tolerability of AHCC in subjects with HPV-positive patients with Head and Neck Squamous Cell Carcinoma. These are subjects who have undergone surgery or will be undergoing surgery.
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
03/24/2025
Locations: Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, California
Conditions: HNSCC, Head and Neck Squamous Cell Carcinoma
Meditative Neurofeedback for Depression
Recruiting
The goal of this open-label single-arm study is to test a meditative neurofeedback intervention for depressed mood.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: University of California San Diego, La Jolla, California
Conditions: Depression - Major Depressive Disorder, Depression Disorders
Investigating the Interaction of Psilocybin and Context of Its Administration in Healthy Volunteers
Recruiting
One hundred twenty healthy participants, ages 21 to 70, who experience moderate-to-lower-than-average mental well-being will be evenly randomized into four different study arms, using a 2x2 factorial design. Depending on the study arm, participants will either receive an inactive placebo or up to 25mg psilocybin (oral dose), in one of two set and setting conditions; drug administration contexts that are predicted to modulate drug effects.
The purpose of this study is to evaluate any interaction... Read More
Gender:
ALL
Ages:
Between 21 years and 70 years
Trial Updated:
03/24/2025
Locations: UCSF Mission Bay, San Francisco, California
Conditions: Healthy Participants with Lower-than-average Mental Well-being
Somatic Dysfunction in Patients With Acute Cerebrovascular Disease
Recruiting
The goals of this observational study are to test the reliability of a new, standardized physical examination method to identify motion problems within joints or groups of joints among adult asymptomatic volunteers and in patients hospitalized with stroke or stroke-like episodes (e.g., transient ischemic attack, TIA). The main questions this investigation aims to answer are:
* Can different, independent providers reliability quantify motion pattern problems using a systematic approach called, T... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: University of California Davis Medical Center, Sacramento, California
Conditions: Stroke, Acute, TIA, Reproducibility of Results, Osteopathic Manipulation, Health-Related Quality-of-Life
2953 - 2964 of 5590
Kaiser Permanente houses over 6,000 physicians in southern California and it is also one of the largest research centers on the state. On its clinical trial division, Kaiser Permanente conducts clinical trials of almost every specialty funded by pharmaceutical companies, government, and foundations.
The Cedars-Sinai Medical Center located in Los Angeles is one of the largest research centers owned and operated by a private hospital in the United States. Focusing on biomedical, cancer, and heart research among other specialties, you can find almost any type of clinical trials for both health and non-healthy volunteers at the research division of Cedar-Sinai Medical Center.
There are around 100,000 clinical trials happening every year across the United States about almost every condition out there. While most clinical trials are testing drugs or medical devices there are also many behavioral and observational trials going on at any point in time. Many paid research studies are held at these California locations.
Clinical trials are incredibly important for making new medical and scientific discoveries, finding new and better methods for diagnosing medical conditions early, testing new interventions, and even developing safer and more effective surgical procedures.
In order for all these discoveries to me made available to the general population they need to go through years of rigorous testing both in healthy and non-healthy volunteers. During those years, medical professionals follow a protocol that has been previously approved by the FDA or other regulatory agency to test the effectiveness and safety of their discovery.
Other people choose to participate in a clinical trial because they feel it is a good way to contribute to the advancement of medical knowledge and that their participation can help many people in the future. The following lists of trials are broken down by condition, and to find a specific clinical trial in your area click through to clinicaltrials.gov.
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