California is currently home to 5616 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Kesimpta (Ofatumumab) Pregnancy Registry
Recruiting
The Kesimpta Pregnancy Registry is an observational, exposure cohort designed study to examine pregnancy and infant outcomes in women and infants who are exposed to Kesimpta (ofatumumab) during pregnancy to treat MS.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/12/2025
Locations: University of California San Diego OTIS, La Jolla, California
Conditions: Multiple Sclerosis, Pregnancy
Project REMOTE (REimagining Measurements and Operations of Translational Endpoints)
Recruiting
This trial is designed to assess immunological biomarkers measured from blood samples that can be used to reliably predict how well vaccines work against symptomatic COVID-19 as well as to evaluate the feasibility of remote, self-collected specimens when conducting a correlates analysis. For a lot of research studies, people need to go to the study doctor's office regularly. For this study, we want to see if it is okay that people do the study doctor visits virtually, fill out questionnaires ele... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/10/2025
Locations: Apex Research Group, Fair Oaks, California
Conditions: COVID-19
BladdEr Full OR Empty for Pelvic Radiation Therapy
Recruiting
The present study evaluates empty and full bladder protocols for radiation therapy of genitourinary (GU), gynecological (Gyn), and gastrointestinal (GI) malignancies of the pelvis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/10/2025
Locations: University of California, San Diego, San Diego, California
Conditions: Pelvic Neoplasm
Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset
Recruiting
The goal of the Tiny Baby Collaborative Multicenter Inventory of Neonatal-Perinatal Interventions (MINI) minimum dataset is to serve as a registry detailing the outcomes and practices for all deliveries and infants admitted to intensive care at 22-23 weeks' gestation at participating hospitals.
Gender:
ALL
Ages:
Between 0 years and 1 year
Trial Updated:
01/10/2025
Locations: Miller Children's & Women's Hospital, Long Beach, California
Conditions: Infant, Extremely Premature, Obstetric Labor, Premature, Premature Birth, Intensive Care, Neonatal, Intensive Care Units, Neonatal
Tissue Destruction and Healing in Celiac Disease
Recruiting
The purpose of this clinical study is to learn more about celiac disease pathogenesis and clinical symptoms. In particular, this study will examine the interactions between biological factors such as, intestinal epithelial cells, microbiota, immune system, genetics, and gluten and their effect on celiac disease clinical symptoms, and severity of tissue destruction and its ability to heal in individuals with celiac disease. Information collected in the study will help researchers to generate bett... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/10/2025
Locations: California Institute of Technology, Pasadena, California
Conditions: Celiac Disease
Phase IIa Trial of a Selective Glucocorticoid Receptor Antagonist in the Treatment of Veterans With Posttraumatic Stress Disorder (PTSD) (Seven Study)
Recruiting
The purpose of this study is to test the drug CORT108297, which blocks the hormone cortisol, for treatment of PTSD in Veterans, and establish a safety profile that will inform the design of future studies.
Gender:
ALL
Ages:
Between 18 years and 69 years
Trial Updated:
01/10/2025
Locations: San Francisco VA Medical Center, San Francisco, CA, San Francisco, California
Conditions: PTSD
Clinical Transcriptomics in Systemic Vasculitis (CUTIS)
Recruiting
Multi-center observational study to evaluate the histopathology and transcriptome of cutaneous lesions in patients with several different types of vasculitis.
Gender:
ALL
Ages:
5 years and above
Trial Updated:
01/10/2025
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Cryoglobulinemic Vasculitis (CV), Drug-induced Vasculitis, Eosinophilic Granulomatosis With Polyangiitis (EGPA), IgA Vasculitis, Isolated Cutaneous Vasculitis, Granulomatosis With Polyangiitis (GPA), Microscopic Polyangiitis (MPA), Polyarteritis Nodosa (PAN), Urticarial Vasculitis, Vasculitis
The Effects of Energy Healing in Fibromyalgia
Recruiting
This study aims to study the clinical effects of Energy Healing using fMRI and determine its application to Fibromyalgia patients. We also want to find out how active Energy Healing compares to sham Energy Healing in terms of brain connectivity and pain interference scores.
Gender:
FEMALE
Ages:
Between 18 years and 75 years
Trial Updated:
01/09/2025
Locations: University of California at Irvine, Irvine, California
Conditions: Fibromyalgia
Telerehabilitation Early After CNS Injury
Recruiting
The goal of this clinical trial is to assess the safety and feasibility of providing extra doses of rehabilitation therapy for persons with a recent stroke, traumatic brain injury (TBI) and/or spinal cord injury (SCI). The therapy treatment targets to improve arm function by introducing telerehabilitation to the bedside of participants during the inpatient rehab admission period. Participants will use a newly developed functional training system (HandyMotion) to access therapy treatment program... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/09/2025
Locations: California Rehabilitation Institute, Los Angeles, California
Conditions: Cerebral Stroke, Traumatic Brain Injury, Spinal Cord Injuries
BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease
Recruiting
This is an open-label, single-arm, multicenter, Phase 1/2 study evaluating the safety and efficacy of the administration of autologous base edited CD34+ HSPCs (BEAM-101) in patients with severe SCD
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
01/09/2025
Locations: Lucile Packard Children's Hospital at Standford, Palo Alto, California
Conditions: Sickle Cell Disease
Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment
Recruiting
Clinical study to investigate the efficacy and safety of savolitinib in combination with osimertinib versus platinum-based doublet chemotherapy in participants with EGFR mutated, MET-overexpressed and/or amplified, locally advanced or metastatic NSCLC who have progressed on treatment with Osimertinib.
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
01/09/2025
Locations: Research Site, La Jolla, California
Conditions: Carcinoma, Non-Small-Cell Lung
Study of INBRX-109 in Conventional Chondrosarcoma
Recruiting
Randomized, blinded, placebo-controlled, Phase 2 study of INBRX-109 in unresectable or metastatic conventional chondrosarcoma patients.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
01/09/2025
Locations: Precision NextGen Oncology & Research Center, Beverly Hills, California
Conditions: Conventional Chondrosarcoma