California is currently home to 5930 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effects of Prompt to Bundle COVID-19 Booster and Flu Shot
Recruiting
This randomized controlled trial investigates whether text-based reminders can increase the bivalent COVID-19 booster uptake and whether text-based reminders that mention the opportunity to bundle the COVID-19 booster with the flu shot within the same appointment can increase take-up of both the COVID-19 booster and the flu vaccine.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/04/2022
Locations: UCLA Health Department of Medicine, Quality Office, Los Angeles, California
Conditions: COVID-19, Vaccines
Evaluation of the Building Healthy Life Skills Program
Recruiting
The goal of this intervention trial is to learn test whether participation in the Building Health Life Skills Program leads to improvements in psychological well-being and stress management skills for people who are experiencing homelessness and housing insecurity. The main questions it aims to answer are: Will participation in the Building Healthy Life Skills Program lead to better skills in managing negative emotions? Will participation in the Building Healthy Life Skills Program lead to impr... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/03/2022
Locations: University of California Merced, Merced, California
Conditions: Adverse Childhood Experiences, Housing Problems, Emotion Regulation
A Latino MSM Focused Pre-Exposure Prophylaxis Uptake Intervention
Recruiting
The clinical study will evaluate the feasibility and acceptability of a culturally tailored behavioral intervention to improve uptake of pre-exposure prophylaxis for HIV prevention among at-risk Latino men who have sex with men.
Gender:
Male
Ages:
18 years and above
Trial Updated:
11/03/2022
Locations: Bienestar Human Services, Los Angeles, California
Conditions: HIV
A 6-Month Extension Study of VMDN-003-2 to Assess Engensis in Participants With Painful Diabetic Peripheral Neuropathy
Recruiting
To evaluate the durability of efficacy and long-term safety of intramuscular (IM) administration of Engensis or Placebo that was administered in the double-blind, randomized, VMDN-003-2 Placebo-controlled Phase 3 Study.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/03/2022
Locations: California Medical Clinic for Headache, Los Angeles, California
Conditions: Diabetic Peripheral Neuropathy
TRUEBEAM Stereotactic Body Radiotherapy for Localized Prostate Cancer
Recruiting
The purpose of this study is to determine the effects of TrueBeam stereotactic body radiosurgery in patients with prostate cancer. The device is designed to concentrate large doses of radiation onto the tumor so that injury from radiation to the nearby normal tissue will be minimal. The purpose of this evaluation is to see if this treatment will help patients with your condition and to evaluate the effect of this treatment on your quality of life over time. Radiosurgery is a non-invasive treatme... Read More
Gender:
Male
Ages:
All
Trial Updated:
11/03/2022
Locations: MemorialCare Saddleback Medical Center, Laguna Hills, California
Conditions: Prostate Cancer
Evaluating the Efficacy of Dual Layer Amniotic Membrane (Artacent®)
Recruiting
A Randomized Controlled Multicenter Clinical Trial, Evaluating the Efficacy of Dual Layer Amniotic Membrane (Artacent®) and Standard of Care versus Standard of Care alone in the healing Chronic Diabetic Foot Ulcers. Multi-center, open label, randomized controlled trial. Study is estimated to require 12 months from first subject enrolled to last subject visit.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/03/2022
Locations: New Hope Podiatry, Los Angeles, California
Conditions: Chronic Diabetic Foot Ulcers
Relative Bioavailability, Safety, and Tolerability of Single-dose Sotrovimab Injection in Adults (COSMIC)
Recruiting
This clinical pharmacology study will evaluate the relative bioavailability, safety, and tolerability of two different concentrations of sotrovimab injections administered at different injection sites in male or female healthy participants aged 18 to 65 years. The study will be conducted in three parts (Part A, an optional Part B and Part C).
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/02/2022
Locations: Investigative Site, Riverside, California
Conditions: Covid19
Adaptive Intervention to Facilitate PrEP Uptake/Adherence Among Transgender Women
Recruiting
"PrEP N' Shine" is a two-stage randomized controlled pilot trial which utilizes a behavioral intervention to optimize the uptake and adherence of Pre-exposure Prophylaxis (PrEP) in Transgender women (TGW).
Gender:
Male
Ages:
18 years and above
Trial Updated:
11/02/2022
Locations: UCLA Center for LGBTQ+ Advocacy, Research & Health, Los Angeles, California
Conditions: Prevention
Integrating Support Persons Into Recovery
Recruiting
INtegrated Support Persons Into Recovery (INSPIRE) is a 4-year research project that tests whether integrating a patient's support person into a patient's treatment with Buprenorphine/Naloxone can improve outcomes. The study will examine whether a counseling program called CRAFT for a support person, such as a family member, spouse or friend, can improve patient outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/02/2022
Locations: Lifelong Medical Care, Berkeley, California
Conditions: Opioid Addiction
VascTrac Peripheral Arterial Disease (PAD) Study
Recruiting
VascTrac is a mobile medical application that tracks users' physical activity levels in order to predict endovascular failure of patients with Peripheral Artery Disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/02/2022
Locations: VA Palo Alto Health Care System, Palo Alto, California
Conditions: Peripheral Artery Disease, Intermittent Claudication
HCRN Core Data Project: Characterizing Patient Populations in the Hydrocephalus Clinical Research Network (HCRN)
Recruiting
The Hydrocephalus Clinical Research Network (HCRN) has been established by philanthropic funding to conduct multi-institutional research (clinical trials and observational studies) on pediatric hydrocephalus. In addition to philanthropic funding, the HCRN has also received an NIH NINDS Challenge Grant to support the network infrastructure which allows for the conduct of this and other network studies. The HCRN consists of multiple Clinical Centers and the Data Coordinating Center (DCC). The HCRN... Read More
Gender:
All
Ages:
18 years and below
Trial Updated:
11/02/2022
Locations: Children's Hospital of Los Angeles, Los Angeles, California
Conditions: Pediatric Hydrocephalus
Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study
Recruiting
A prospective multicenter observational study, led by Dr. Katie Russell of Intermountain Primary Children's Hospital, that will examine the sensitivity, specificity, negative, and positive predictive values of CT scan and plain films in diagnosing cervical spine injury that requires treatment. This study is funded by the Primary Children's Hospital foundation.
Gender:
All
Ages:
Between 0 years and 17 years
Trial Updated:
11/01/2022
Locations: Children's Hospital Los Angeles, Los Angeles, California
Conditions: Cervical Spine Fracture