California is currently home to 5587 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Genicular Artery Embolization Vs Observation for Symptomatic Knee Osteoarthritis
Recruiting
The purpose of this clinical trial is to determine whether genicular artery embolization (GAE) is an effective way to treat knee pain from osteoarthritis. Pain from arthritis is often due to underlying inflammation in the joint. The inflammation is associated with increased abnormal blood flow going to the specific area of pain. If the investigator can reduce the blood flow, the inflammation can be reduced and the pain can be controlled. The GAE procedure is an experimental procedure to decreas... Read More
Gender:
ALL
Ages:
Between 40 years and 79 years
Trial Updated:
09/28/2024
Locations: UCLA Santa Monica Hospital, Santa Monica, California
Conditions: Knee Osteoarthritis, Degenerative Joint Disease of Knee
Magnetic Resonance Imaging for Improving Knowledge of Brain Tumor Biology in Patients With Resectable Glioblastoma
Recruiting
This clinical trial uses a type of imaging scan called magnetic resonance imaging (MRI) to study brain tumor biology in patients with glioblastoma that can be removed by surgery (resectable). Malignant gliomas are the second leading cause of cancer mortality in people under the age of 35 in the United States. Glioblastoma is a type of malignant glioma with very poor patient prognosis. There are currently only about 3 drugs approved by the Food and Drug Administration (FDA) for the treatment of g... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/27/2024
Locations: UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California
Conditions: Glioblastoma, Recurrent Glioblastoma, Resectable Glioblastoma
Efficacy of mHealth Applications in Weight Management in a Population Affected by Overweight or Obesity
Recruiting
The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes in patients with overweight and obesity. This study will involve a 6-month long commitment where participants will be expected to use an mHealth app daily, weigh themselves and check their fasting blood glucose levels every morning.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
09/27/2024
Locations: San Diego State University, San Diego, California
Conditions: Overweight and Obesity
Efficacy of Using Mobile Health Applications for Health
Recruiting
The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes and type II diabetes outcomes in type 2 diabetics. This study will involve a 6-month long commitment where participants will be expected to weigh themselves every morning, at the same time, and check their blood glucose readings daily before and after meals for at least three meals in the day.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
09/27/2024
Locations: San Diego State University, San Diego, California
Conditions: Diabetes Mellitus, Type 2, Obesity
Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population
Recruiting
The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes and the subsequent benefit of improving type II diabetes outcomes in a low socioeconomic Hispanic population. This study will involve a 6-month long commitment where participants will be expected to weigh themselves every morning, at the same time, and check their blood glucose readings daily before and after meals for at least three meals in the day.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
09/27/2024
Locations: San Diego State University, San Diego, California
Conditions: Diabetes Mellitus, Type 2, Obesity
Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma
Recruiting
This clinical trial constructs and tests a novel multinuclear metabolic magnetic resonance imaging (MRI) sequence in patients with glioma (brain tumor) that is newly diagnosed or has come back (recurrent). This trial aims to develop new diagnostic imaging technology that may bridge gaps between early detection and diagnosis, prognosis, and treatment in brain cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/27/2024
Locations: UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California
Conditions: Glioma, Malignant Glioma, Recurrent Glioma, Recurrent Malignant Glioma
A Phase 3 Study of the Safety and Efficacy of Coagulation Factor VIIa (Recombinant) for the Prevention of Excessive Bleeding in Patients With Congenital Hemophilia A or B With Inhibitors to Factor VIII or IX Undergoing Elective Major Surgical Procedures SCOPE HIM
Recruiting
This is an interventional, prospective, international, multicenter, single-arm, Phase 3, and sequential efficacy and safety study in adolescents and adults with congenital hemophilia A or B with inhibitors to factor VIII (FVIII) or factor IX (FIX) undergoing elective major surgical procedures.
Gender:
MALE
Ages:
Between 12 years and 65 years
Trial Updated:
09/26/2024
Locations: Orthopaedic Institute for Children - Orthopaedic Hemophilia Treatment Center, Los Angeles, California
Conditions: Hemophilia
Remote Patient Monitoring and Health Coaching vs. Usual Care for the Treatment of Hypertension
Recruiting
High blood pressure, also known as hypertension, affects nearly half of all Americans and increases the risk for heart disease and stroke. Only about half of people with high blood pressure have it under control. New methods to control blood pressure are needed to reduce heart attack and stroke rates. The purpose of this study is to test whether a digital program that includes personalized health coaching and remote patient monitoring with a connected blood pressure cuff, all delivered on a smar... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: Stanford University, Redwood City, California
Conditions: Hypertension
Interventions in Mathematics and Cognitive Skills
Recruiting
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning disabilities (MLD).
Gender:
ALL
Ages:
Between 6 years and 12 years
Trial Updated:
09/26/2024
Locations: Stanford Cognitive and Systems Neuroscience Laboratory, Palo Alto, California
Conditions: Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities, Learning Disabled, Learning Curve, Mathematics Disorder, Dyscalculia, Dyscalculia, Primary, Dyscalculia, Acquired, Specific Learning Disorder, With Impairment in Mathematics, Individuality, Behavior, Child, Behavior and Behavior Mechanisms, Behavior, Decision Making, Neuronal Plasticity, Cognition, Cognition Disorder, Cognitive Dysfunction, Cognitive Change, Cognitive Impairment, Mild, Cognitive Developmental Delay, Cognitive Orientation, Cognitive Delay, Mild, Cognitive Deficits, Mild, Cognitive Abnormality, Neuroscience
Olorofim Aspergillus Infection Study
Recruiting
The purpose of this study is to compare treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with IFD caused by proven IA or probable lower respiratory tract disease Aspergillus species (invasive aspergillosis, IA).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: City of Hope National Medical Center, Duarte, California
Conditions: Invasive Aspergillosis
Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout
Recruiting
The TRUST study is a randomized, controlled multicenter study to evaluate the management of gout by comparing two commonly used treatment strategies for gout (TTT vs TTASx) to determine the most beneficial for a patient-centered gout outcomes, as well as relevant cardiovascular-metabolic-renal endpoints.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
09/26/2024
Locations: UCLA Health, Santa Monica, California
Conditions: Gout
Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination with XELOX or Irinotecan in Patients with Advanced Gastric Cancer
Recruiting
This is an open-label, Phase 1b/2a study to evaluate the safety and tolerability of IDX-1197 and determine the MTD and RP2D in combination with XELOX or irinotecan in patients with advanced gastric cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: USC Norris Comp. Cancer Ctr Hospital, Los Angeles, California
Conditions: Gastric Cancer