California is currently home to 5618 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Blood Specimen Collection For Laboratory Assay Research
Recruiting
To collect lab data from capillary and venous blood specimens for use in analytical research studies to support the development and validation of laboratory procedures.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: Roman Health Ventures Study Site, San Francisco, California
Conditions: General; Metabolic Disorder, Sexual Dysfunction, Hair Loss, Pathology
Crisis Response Planning for Military Personnel
Recruiting
The study is a randomized trial comparing outcomes of active duty service members who present to the emergency department at risk for suicide and receive care from providers trained in crisis response planning versus those providing treatment as usual.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: Naval Medical Center San Diego, San Diego, California
Conditions: Suicidal, Suicide Threat, Suicidal Ideation
Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis
Recruiting
The goal of this study is to test the safety of drug, Belantamab Mafodotin, and see what effects (good and bad) it has on people who take it and amyloidosis, and to determine the most effective dose of the drug. The study will have 2 phases (parts). The first phase of the study will test different doses of Belantamab Mafodotin. The second phase will test Belantamab Mafodotin at the dose level found to be safe and effective in phase 1
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: Stanford Cancer Institute, Stanford, California
Conditions: AL Amyloidosis, Amyloidosis
Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia
Recruiting
To evaluate the safety and effectiveness of the PXL Platinum 330 system for performing corneal cross-linking (CXL) for the treatment of ectatic disorders.
Gender:
ALL
Ages:
10 years and above
Trial Updated:
11/13/2024
Locations: Goodman Eye Center, San Francisco, California
Conditions: Keratoconus, Pellucid Marginal Corneal Degeneration, Corneal Ectasia
Endovascular Exclusion of Thoracoabdominal And/or Paravisceral Abdominal Aortic Aneurysm
Recruiting
This is a study to assess the safety and effectiveness of endovascular treatment of thoracoabdominal (TAAA) and paravisceral abdominal (PVAAA) aortic aneurysms. The investigational operation involves placing a stent-graft over the aortic aneurysm.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: Division of Vascular Surgery, SFVAMC, San Francisco, California
Conditions: Thoracoabdominal Aortic Aneurysm, Paravisceral Abdominal Aortic Aneurysm
DBT for Smoking Cessation in High Risk Veterans
Recruiting
Individuals prone to suicidality are typically excluded from tobacco cessation interventions even though they are disproportionately likely to smoke, and even though smoking cessation has been linked to improved mood and reduced risk of suicide. This trial enrolls Veteran smokers at high risk for suicide, and assigns them to receive either cessation treatment as usual, or a novel treatment that incorporates standard behavioral cessation treatment with Dialectical Behavior Therapy (DBT), an evid... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Veterans Medical Research Foundation, San Diego, California
Conditions: Tobacco Dependence, Suicidal
A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations
Recruiting
This study will compare Valemetostat Tosylate Plus Pembrolizumab vs Pembrolizumab Alone in First-line NSCLC Without Actionable Genomic Alterations
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: University of California San Diego (Ucsd)-Moores Cancer Center, La Jolla, California
Conditions: Non-small Cell Lung Cancer, Lung Cancer
Radicle Spark for Men 24: A Study of Health and Wellness Products on Sexual Health and Related Health Outcomes
Recruiting
A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on sexual health and related health outcomes
Gender:
MALE
Ages:
Between 21 years and 105 years
Trial Updated:
11/12/2024
Locations: Radicle Science, Inc, Del Mar, California
Conditions: Sexual Satisfaction, Sexual Function
FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases
Recruiting
FLOWER is a completely virtual, nationwide, real-world observational study to collect, annotate, standardize, and report clinical data for rare diseases. Patients participate in the study by electronic consent (eConsent) and sign a medical records release to permit data collection. Medical records are accessed from institutions directly via eFax or paper fax, online from patient electronic medical record (EMR) portals, direct from DNA/RNA sequencing and molecular profiling vendors, and via elect... Read More
Gender:
ALL
Ages:
All
Trial Updated:
11/12/2024
Locations: xCures, Los Altos, California
Conditions: Alpha-Thalassemia, Beta-Thalassemia, Amyloidosis, Amyotrophic Lateral Sclerosis, Creutzfeld-Jakob Disease, Cystic Fibrosis, Duchenne Muscular Dystrophy, Early-Onset Alzheimer Disease, Ehlers-Danlos Syndrome, Huntington Disease, Gaucher Disease, GM1 Gangliosidosis, Myasthenia Gravis, Pompe Disease, Sickle Cell Disease, Transthyretin Amyloid Cardiomyopathy, Rare Diseases
Work Time Schedule Changes for Nurse Managers
Recruiting
The goal of this clinical trial is to explore how working a 4-day schedule impacts nurse manager wellbeing and job performance. The main questions it aims to answer are: * Do those working 4-days have improved wellbeing with reduced levels of burnout and work/family conflict when compared to those in the control group? * Do levels of sleep, heart rate variability, and physical activity significantly differ between those working the 4-day schedule change and those in the control group? * Are nur... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Ronald Reagan UCLA Medical Center, Los Angeles, California
Conditions: Work-Related Condition
ADSTILADRIN Early Utilization and Outcomes in the Real World Setting
Recruiting
Multi-center, prospective non-interventional study to collect data on the early use of Adstiladrin in the US and Israel. Data will be collected from patients and prescribing physicians in a real-world setting
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Ferring Investigational Site, Fresno, California
Conditions: Bladder Cancer
Comparative Effectiveness of Online 8-session CBT Vs. 1-Session Empowered Relief for Chronic Pain - the PROGRESS Study
Recruiting
The purpose of this study is to conduct a pragmatic clinical trial comparing the effectiveness of: (1) 8-week cognitive behavioral therapy for chronic pain (pain-CBT; sixteen hours total treatment time); and (2) a 1-session pain relief skills intervention for chronic pain (Empowered Relief; two hours total treatment time).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: SCAN Health Plan, Long Beach, California
Conditions: Pain, Chronic, Lupus, Pelvic Pain