California is currently home to 5602 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy
Recruiting
To use a consistent and standardized platform to retrospectively and prospectively study children and young adults with B cell malignancies receiving Immunotherapy, blinatumomab and/or inotuzumab ozogamicin.
Gender:
ALL
Ages:
26 years and below
Trial Updated:
10/17/2024
Locations: Stanford University, Palo Alto, California
Conditions: Lymphoid Leukemia
Weighted Blankets for Postsurgical Pain
Recruiting
The strongest psychological predictor of persistent pain after surgery is anxiety before surgery. The weight of blanket a person uses overnight may alter both anxiety and pain levels. The proposed study will determine whether a heavier or lighter blanket alters presurgical anxiety or postsurgical pain in individuals undergoing a breast surgery. We will also study whether any blanket-induced changes in postsurgical pain are related to reductions in anxiety before surgery induced by the blanket. F... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/17/2024
Locations: Actri, Ucsd, La Jolla, California
Conditions: Pain, Postsurgical
Magnetic Apnea Prevention(MAGNAP) Device to Treat Obstructive Sleep Apnea:First-In-Human Study of Feasibility and Safety
Recruiting
The purpose of this study is to determine the safety and feasibility of the Magnap magnetic device in the treatment of obstructive sleep apnea (OSA).
Gender:
ALL
Ages:
Between 21 years and 70 years
Trial Updated:
10/17/2024
Locations: University of California San Francisco/Mount Zion Hospital, San Francisco, California
Conditions: Obstructive Sleep Apnea
Fall Risk Assessment and Speech Intelligibility Enhancement Using In-ear Device
Recruiting
The purpose of this study is to develop and validate methods to use hearing aids equipped with embedded sensors and artificial intelligence to assist in the assessment of fall risk and in the implementation of interventions aimed at reducing the risk of falling, as well as to improve speech intelligibility in quiet and in background noise, track physical activity, and social engagement. The investigators hope is that the knowledge that is generated through this study will ultimately translate to... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
10/16/2024
Locations: Stanford Ear Institute, Palo Alto, California
Conditions: Hearing Loss, Dizziness, Vertigo, Fall Related Injury Risk, Fall Prevention, Imbalance, Speech Intelligibility
Human Embryonic Stem Cell-Derived Cardiomyocyte Therapy for Chronic Ischemic Left Ventricular Dysfunction
Recruiting
This clinical study will utilize a new cell therapy approach (Human embryonic stem cells derived cardiomyocytes or hESC-CMs) to improve survival and cardiac function in patients with chronic left ventricular dysfunction secondary to MI (Myocardial Infarction).
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
10/16/2024
Locations: Stanford Hospital and Clinics, Palo Alto, California
Conditions: Chronic Ischemic Left Ventricular Dysfunction
A Study of the Natural History of Participants With LGMD2E/R4, LGMD2D/R3, LGMD2C/R5, and LGMD2A/R1 ≥ 4 Years of Age, Who Are Managed in Routine Clinical Practice
Recruiting
This study will follow participants who are screened and confirmed with a genetic diagnosis of Limb-girdle muscular dystrophy type 2E (LGMD2E/R4), Limb-girdle muscular dystrophy type 2D (LGMD2D/R3), Limb-girdle muscular dystrophy type 2C (LGMD2C/R5), or Limb-girdle muscular dystrophy type 2A (LGMD2A/R1). These enrolled participants will be followed to evaluate mobility and pulmonary function for up to 5 years after enrollment for participants with LGMD2C/R5, LGMD2D/R3, and LGMD2E/R4 with a Nort... Read More
Gender:
ALL
Ages:
4 years and above
Trial Updated:
10/16/2024
Locations: University of California San Diego, La Jolla, California
Conditions: Limb-girdle Muscular Dystrophy
Effects of Common Meals on Appetite and Satiety
Recruiting
The objectives of this study are to assess the impacts of meals composed of lean steak and potatoes (with a small portion of broccoli) in comparison to other common entrée/starch food combinations on metabolic and appetite responses.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
10/15/2024
Locations: San Diego State University, San Diego, California
Conditions: Healthy
Diluted Aqueous Povidone-Iodine Compared to Saline to Decrease Surgical Site Infections
Recruiting
This is a multicenter randomized controlled trial of 1100 patients to evaluate the superiority of combined intraoperative wound irrigation with intraoperative peritoneal lavage with dilute aqueous povidone-iodine compared to normal saline in male and female patients between the ages of 18 and 80 years old undergoing emergency laparotomies with Centers for Disease Control (CDC) class 2 and 3 wounds.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
10/15/2024
Locations: Loma Linda University Health, Loma Linda, California
Conditions: Surgical Site Infection
The Acute and Accumulative Effects of Snack Foods on Exercise Recovery
Recruiting
The purpose of the research is two-fold. One goal is to determine if post-exercise almond or cereal bar consumption can promote muscle gain as well as increasing muscular strength throughout an eight-week weight training program. The other goal is to assess the short-term effects of almonds or cereal bar on recovery that may explain the overall long-term adaptations.
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
10/15/2024
Locations: San Diego State University, San Diego, California
Conditions: Muscle Strength
Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients
Recruiting
The study will have two separate patient cohorts: Cohort 1 will include patients with newly diagnosed chronic graft versus host disease (GVHD), whereas cohort 2 will include patients with newly diagnosed chronic lung disease (CLD). For cohort 1, the primary objective will be to characterize PRM metrics at the onset of chronic GVHD and determine if a PRM signature is present that will predict 1-year CLD free survival. For cohort 2, the primary objective will focus on characterizing PRM at the ons... Read More
Gender:
ALL
Ages:
36 months and above
Trial Updated:
10/15/2024
Locations: Stanford Hospital, Stanford, California
Conditions: Chronic Lung Disease, Hematopoietic Cell Transplantation, Graft Versus Host Disease
Building Resilient Families
Recruiting
Prior research suggests that it is possible to improve health outcomes in children with ACEs through multi-component interventions. The challenge for most communities is that health and education systems are fragmented and fail to accommodate families based upon different levels of need. This study utilizes cross-sectoral partnerships to mobilize three vectors (pediatricians, community health workers and parenting educators) to optimize the delivery of vital information and resources to a divers... Read More
Gender:
ALL
Ages:
Between 3 years and 11 years
Trial Updated:
10/15/2024
Locations: Loma Linda University, Loma Linda, California
Conditions: Adverse Childhood Experiences
Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients
Recruiting
The primary purpose of this multi-center, double-blind, placebo-controlled, dose-ranging Phase I study is to assess the safety of a purified from green tea, EGCG, in patients with idiopathic pulmonary fibrosis (IPF) as a potential novel treatment for pulmonary fibrosis.
Gender:
ALL
Ages:
Between 40 years and 85 years
Trial Updated:
10/15/2024
Locations: UCSF Parnassus, San Francisco, California
Conditions: Idiopathic Pulmonary Fibrosis