California is currently home to 5605 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Systems Biology of Early Atopy
Recruiting
The goal of this study is to establish a birth cohort that collects prenatal and early life biosamples and environmental samples and rigorously phenotypes young children for food allergy and Atopic Dermatitis (AD) to identify prenatal and early life markers of high risk for food allergy and AD, as well as biological pathways (endotypes) that result in these conditions. Primary Objectives: * To study the role and interrelationships of established and novel clinical, environmental, biological, a... Read More
Gender:
ALL
Ages:
0 years and above
Trial Updated:
04/23/2024
Locations: Sean N. Parker Center for Allergy & Asthma Research at Stanford University, Stanford, California
Conditions: Allergic Diseases, Food Allergy, Atopic Dermatitis
Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer
Recruiting
The performance of SGM-101, an intraoperative imaging agent, will be compared to that of standard "white light" visualization during surgical resections of colorectal cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: City of Hope National Medical Center, Duarte, California
Conditions: Colorectal Neoplasms
Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease
Recruiting
The goal of this observational study is to help us understand more about the best ways to help individuals living with Sickle Cell Disease (SCD) get the best care. The main question it aims to answer is: How to find individuals unaffiliated from SCD specialist care use three distinct pathways? Once unaffiliated individuals are found using the pathways, Investigators will employ linkage coordinators (trained staff) to engage these patients in care. Participants will be asked to fill out an assess... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2024
Locations: University of California, San Francisco (UCSF), Oakland, California
Conditions: Sickle Cell Disease
Pilot Study of Pancreatic Cancer Screening
Recruiting
This study investigates how often abnormal findings from routine magnetic resonance imaging occur in people with genetic mutations in BReast CAncer gene. (BRCA), ataxia telangiectasia mutated gene (ATM), or PALB2 screened for pancreatic cancer. This study may lead to a greater understanding of cancer and potentially, improvements in cancer screening and treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2024
Locations: University of California San Francisco, San Francisco, California
Conditions: Pancreatic Carcinoma
Wide-Area Transepithelial Sampling in Endoscopic Eradication Therapy for Barrett's Esophagus
Recruiting
Esophageal cancer is a deadly disease that is becoming increasingly common in the United States. Barrett's esophagus (BE) is a pre-cancerous state that can develop into esophageal cancer, but is highly treatable. Progression of BE to esophageal cancer is still common due to missed diagnosis of Barrett's esophagus recurrence following treatment. Wide-Area Trans-Epithelial Sampling (WATS-3D) is a new technology that uses brush sampling to examine larger areas of the esophagus as compared to conven... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2024
Locations: University of California, LA, Los Angeles, California
Conditions: Barrett Esophagus, Esophageal Cancer
Immediate Postpartum Glucose Tolerance Testing
Recruiting
The objective of this study is to compare the accuracy of a 2hr glucose tolerance test administered during the postpartum hospitalization with the standard of care glucose tolerance testing (administered at 6 weeks postpartum). The primary hypothesis is that the glucose tolerance test administered in the postpartum period will be accurate and will improve compliance with postpartum testing for gestational diabetics.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/22/2024
Locations: Long Beach Memorial Medical Center/Miller Children's and Women's Hospital, Long Beach, California
Conditions: Gestational Diabetes
A Study of ATG-031 in Advanced Solid Tumors or B-cell Non-Hodgkin Lymphomas
Recruiting
ATG-031 study (alias: PERFORM) is a multicenter, open-label, Phase 1 study of ATG-031 in patients with advanced solid tumors or B-NHL. The study design includes a Dose Escalation Phase and a Dose Expansion Phase, and will enroll patients with advanced solid tumors (i.e., preferred tumor types) or relapsed/refractory (R/R) B-NHLs. The study's primary objective is to evaluate the safety and tolerability of ATG-031 and determine the RP2D(Refered Phase II dose) of ATG-031.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/19/2024
Locations: University of California San Francisco (UCSF), San Francisco, California
Conditions: Advanced Solid Tumors, B-cell Non-Hodgkin Lymphomas
Can Nitrous Oxide (Laughing Gas) be Used as a Sedative for GI Endoscopy Procedures?
Recruiting
Nitrous oxide (commonly known as 'laughing gas') is often used during dental and other outpatient procedures, because it is easy to administer, is short-acting and rapidly clears from the body following the procedure. The investigators hypothesize that use of Nitrous oxide during GI endoscopy may enhance patient comfort during the procedure and speed-up post-procedure recovery, while minimizing the fatigue and mental fogginess some patients report the day after receiving standard sedative and n... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/19/2024
Locations: Stanford University Hospital, Stanford, California
Conditions: Endoscopy, Colonoscopy
Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women
Recruiting
The objective of this study is to examine if calcium and vitamin D supplements and/or prune can prevent bone loss in postmenopausal women.
Gender:
FEMALE
Ages:
All
Trial Updated:
04/18/2024
Locations: San Diego State University, San Diego, California
Conditions: Bone Disease, Metabolic
Behavioral and Neuronal Correlates of Human Mood States
Recruiting
Optimizing treatments in mental health requires an easy to obtain, continuous, and objective measure of internal mood. Unfortunately, current standard-of-care clinical scales are sparsely sampled, subject to recency bias, underutilized, and are not validated for acute mood monitoring. The recent shift to remote care also requires novel methods to measure internal mood. Recent advances in computer vision have allowed the accurate quantification of observable speech patterns and facial representat... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/18/2024
Locations: Stanford University, Stanford, California
Conditions: Major Depressive Disorder, Epilepsy
Ancora-SB Overtube Complete Positioning and Optical Visualization During Endoscopic Procedures
Recruiting
Demonstrate superiority of the Aspero Medical Ancora-SB balloon Overtube compared to the Olympus ST-SB1 Balloon Overtube.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
04/18/2024
Locations: Cedars Sinai, Los Angeles, California
Conditions: Small Bowel Disease
Bedside Ultrasonic Assessment for Gastric Content in Patients With Upper GI Bleeding Undergoing Endoscopy: a Pilot Study
Recruiting
Emerging studies have evaluated POCUS (Point of Care Ultrasound) for assessing of gastric content prior to anesthesia to reduce the risk of aspiration and demonstrated that POCUS can accurately identify presence of gastric food or fluid. Despite accumulating studies evaluating POCUS as a diagnostic modality to evaluate for gastric food content prior to anesthesia, there is no study to date that has evaluated the role of POCUS prior to endoscopy among patients with upper GI bleeding. Therefore, t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/18/2024
Locations: Loma Linda University Medical Center, Loma Linda, California
Conditions: Upper GI Bleeding, Point of Care Ultrasound, Upper Endoscopy, Gastric Content, GI Bleed